Advances in Brief:

Heterogeneity of erbB-2 Gene Amplification in Bladder Cancer

G. Sauter, H. Moch, D. Moore, P. Carroll, R. Kerschmann, K. Chew, M.J. Mihatsch, F. Gudat, and F. Waldman
Cancer Res 1993 53: 2199-2203. [Abstract] [PDF]  

Interstitial Pressure of Subcutaneous Nodules in Melanoma and Lymphoma Patients: Changes during Treatment

Brendan D. Curti, Walter J. Urba, W. Gregory Alvord, John E. Janik, John W. Smith, II, Karen Madara, and Dan L. Longo
Cancer Res 1993 53: 2204-2207. [Abstract] [PDF]  

Elevated Levels of M_r 92,000 Type IV Collagenase in Human Brain Tumors

Jasti S. Rao, Peter A. Steck, Sanjeeva Mohanam, William G. Stetler-Stevenson, Lance A. Liotta, and Raymond Sawaya
Cancer Res 1993 53: 2208-2211. [Abstract] [PDF]  

Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents

Roy B. Tishler, Stuart K. Calderwood, C. Norman Coleman, and Brendan D. Price
Cancer Res 1993 53: 2212-2216. [Abstract] [PDF]  

1,25-Dihydroxyvitamin D₃ Enhances 12-O-Tetradecanoylphorbol-13-acetate-induced Tumorigenic Transformation and Osteopontin Expression in Mouse JB6 Epidermal Cells

Pi-Ling Chang and Charles W. Prince
Cancer Res 1993 53: 2217-2220. [Abstract] [PDF]  

High Efficiency Gene Transfer into Primary Human Tumor Explants without Cell Selection

Elizabeth M. Jaffee, Glenn Dranoff, Lawrence K. Cohen, Karen M. Hauda, Shirley Clift, Fray F. Marshall, Richard C. Mulligan, and Drew M. Pardoll
Cancer Res 1993 53: 2221-2226. [Abstract] [PDF]  

Acquisition of Resistance to Antifolates Caused by Enhanced -Glutamyl Hydrolase Activity

Myung S. Rhee, Ying Wang, M. Gopal Nair, and John Galivan
Cancer Res 1993 53: 2227-2230. [Abstract] [PDF]  

p53 Mutation and MDM2 Amplification in Human Soft Tissue Sarcomas

Fredrick S. Leach, Takashi Tokino, Paul Meltzer, Marilee Burrell, Jonathan D. Oliner, Sharon Smith, David E. Hill, David Sidransky, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1993 53: 2231-2234. [Abstract] [PDF]  

Overexpression of p53 Is a Late Event in the Development of Malignant Melanoma

N. J. Lassam, L. From, and H. J. Kahn
Cancer Res 1993 53: 2235-2238. [Abstract] [PDF]  

Perspectives in Cancer Research:

Suramin: A Novel Antineoplastic Agent with Multiple Potential Mechanisms of Action

C. A. Stein
Cancer Res 1993 53: 2239-2248. [PDF]  

Biochemistry and Biophysics:

Ultraviolet Radiation-induced DNA Damage and Its Photorepair in the Skin of the Platyfish Xiphophorus

Farid E. Ahmed and R. B. Setlow
Cancer Res 1993 53: 2249-2255. [Abstract] [PDF]  

Insulin-like Growth Factor 1 Receptors Are Increased in Estrogen-induced Kidney Tumors

Satya Narayan and Deodutta Roy
Cancer Res 1993 53: 2256-2259. [Abstract] [PDF]  

Phosphorylation of Elongation Factor 2 in Normal and Malignant Rat Glial Cells

Danita M. Bagaglio, Elaine H. C. Cheng, Fred S. Gorelick, Ken-ichi Mitsui, Angus C. Nairn, and William N. Hait
Cancer Res 1993 53: 2260-2264. [Abstract] [PDF]  

Carcinogenesis:

Gene Expression and Cell Proliferation in Rat Liver after 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure

Tony R. Fox, Lang L. Best, Susan M. Goldsworthy, Jeremy J. Mills, and Thomas L. Goldsworthy
Cancer Res 1993 53: 2265-2271. [Abstract] [PDF]  

Increased Expression of Specific Protein Tyrosine Phosphatases in Human Breast Epithelial Cells Neoplastically Transformed by the neu Oncogene

Yi-Fan Zhai, Howard Beittenmiller, Bingcheng Wang, Michael N. Gould, Cori Oakley, Walter J. Esselman, and Clifford W. Welsch
Cancer Res 1993 53: 2272-2278. [Abstract] [PDF]  

Inactivation of Plasmid Reporter Gene Expression by One Benzo(a)pyrene Diol-Epoxide DNA Adduct in Adult Rat Hepatocytes

Katherine S. Koch, Raymond G. Fletcher, Martina P. Grond, Austin I. Inyang, Xian P. Lu, David A. Brenner, and Hyam L. Leffert
Cancer Res 1993 53: 2279-2286. [Abstract] [PDF]  

Retinoid Status Controls the Appearance of Reserve Cells and Keratin Expression in Mouse Cervical Epithelium

Nadine Darwiche, Giulia Celli, Linda Sly, Francesca Lancillotti, and Luigi M. De Luca
Cancer Res 1993 53: 2287-2299. [Abstract] [PDF]  

Clinical Investigations:

Local Control of T2/3 Transitional Cell Carcinoma of Bladder Is Correlated to Differences in DNA Supercoiling: Evidence for Two Discrete Tumor Populations

Andrew T. M. Vaughan, Philip Anderson, D. Michael, A. Wallace, Ronald P. Beaney, and Thomas H. Lynch
Cancer Res 1993 53: 2300-2303. [Abstract] [PDF]  

Phase I Study of Amonafide Dosing Based on Acetylator Phenotype

Mark J. Ratain, Rosemarie Mick, Frances Berezin, Linda Janisch, Richard L. Schilsky, Nicholas J. Vogelzang, and L. Brian Lane
Cancer Res 1993 53: 2304-2308. [Abstract] [PDF]  

Endocrinology:

Steroid Production in Different Parts of Malignant and Benign Ovarian Tumors in Vitro

Mona Ridderheim, Carl Gustav Mählck, Gunnar Selstam, Ulf Stendahl, and Torbjörn Bäckström
Cancer Res 1993 53: 2309-2312. [Abstract] [PDF]  

Epidemiology:

The Glutathione S-Transferase µ Polymorphism as a Marker for Susceptibility to Lung Carcinoma

Valle Nazar-Stewart, Arno G. Motulsky, David L. Eaton, Emily White, Sigrid K. Hornung, Zhong-Tai Leng, Pat Stapleton, and Noel S. Weiss
Cancer Res 1993 53: 2313-2318. [Abstract] [PDF]  

Experimental Therapeutics:

Comparison of the Therapeutic Effects of a New Arotinoid, Ro 40-8757, and All-trans- and 13-cis-Retinoic Acids on Rat Breast Cancer

Kampe Teelmann, Toshiyuki Tsukaguchi, Michael Klaus, and James F. Eliason
Cancer Res 1993 53: 2319-2325. [Abstract] [PDF]  

The Role of Active Oxygen Species and Lipid Peroxidation in the Antitumor Effect of Hyperthermia

Toshikazu Yoshikawa, Satoshi Kokura, Kenzo Tainaka, Kenji Itani, Hirokazu Oyamada, Toshiro Kaneko, Yuji Naito, and Motoharu Kondo
Cancer Res 1993 53: 2326-2329. [Abstract] [PDF]  

Effects of Human Papillomavirus Type 18-specific Antisense Oligonucleotides on the Transformed Phenotype of Human Carcinoma Cell Lines

Cherrilee Steele, Lex M. Cowsert, and Edward J. Shillitoe
Cancer Res 1993 53: 2330-2337. [Abstract] [PDF]  

Intraarterial Therapy of Human Glioma Xenografts in Athymic Rats Using 4-Hydroperoxycyclophosphamide

James M. Schuster, Henry S. Friedman, Gary E. Archer, Herbert E. Fuchs, Roger E. McLendon, O. Michael Colvin, and Darell D. Bigner
Cancer Res 1993 53: 2338-2343. [Abstract] [PDF]  

Biochemical Consequences of Resistance to Tiazofurin in Human Myelogenous Leukemic K562 Cells

Hiremagalur N. Jayaram, Weining Zhen, and Kamran Gharehbaghi
Cancer Res 1993 53: 2344-2348. [Abstract] [PDF]  

Etoposide-induced Apoptosis in Human HL-60 Cells Is Associated with Intracellular Acidification

Michael A. Barry, Jason E. Reynolds, and Alan Eastman
Cancer Res 1993 53: 2349-2357. [Abstract] [PDF]  

Immunology:

Mechanisms of Adoptive Immunotherapy: Improved Methods for in Vivo Tracking of Tumor-infiltrating Lymphocytes and Lymphokine-activated Killer Cells

Paul K. Wallace, Larry D. Palmer, Donna Perry-Lalley, Ellen S. Bolton, Richard B. Alexander, Paul K. Horan, James C. Yang, and Katharine A. Muirhead
Cancer Res 1993 53: 2358-2367. [Abstract] [PDF]  

Delivery of Radionuclides to Pretargeted Monoclonal Antibodies Using Dihydrofolate Reductase and Methotrexate in an Affinity System

Gregory A. Hawkins, Richard P. McCabe, Chong-Ho Kim, Ramaswamy Subramanian, Reinhard Bredehorst, Gregory A. McCullers, Carl-Wilhelm Vogel, Michael G. Hanna, Jr., and Nicholas Pomato
Cancer Res 1993 53: 2368-2373. [Abstract] [PDF]  

Expression of HLA Class I Antigens in Sporadic Adenomas and Histologically Normal Mucosa of the Colon

George J. Tsioulias, George Triadafilopoulos, Edward Goldin, Efstathios D. Papavassiliou, Spyros Rizos, Pelopidas Bassioukas, and Basil Rigas
Cancer Res 1993 53: 2374-2378. [Abstract] [PDF]  

Molecular Biology and Genetics:

Differential Expression of the Epidermal Growth Factor Receptor and Its Ligands in Primary Non-Small Cell Lung Cancers and Adjacent Benign Lung

V. Rusch, J. Baselga, C. Cordon-Cardo, J. Orazem, M. Zaman, S. Hoda, J. McIntosh, J. Kurie, and E. Dmitrovsky
Cancer Res 1993 53: 2379-2385. [Abstract] [PDF]  

Loss of Heterozygosity for Loci on Chromosome 10 Is Associated with Morphologically Malignant Meningioma Progression

Sandra A. Rempel, Karl Schwechheimer, Richard L. Davis, Webster K. Cavenee, and Mark L. Rosenblum
Cancer Res 1993 53: 2386-2392. [Abstract] [PDF]  

Human Epithelial Ovarian Cancer Allelotype

W. Cliby, S. Ritland, L. Hartmann, M. Dodson, K. C. Halling, G. Keeney, K. C. Podratz, and R. B. Jenkins
Cancer Res 1993 53: 2393-2398. [Abstract] [PDF]  

Concerted Control of Multiple Histone Promotoer Factors during Cell Density Inhibition of Proliferation in Osteosarcoma Cells: Reciprocal Regulation of Cell Cycle-controlled and Bone-related Genes

Fusinita M. I. van den Ent, Andre J. van Wijnen, Thomas J. Last, Rita Bortell, Janet L. Stein, Jane B. Lian, and Gary S. Stein
Cancer Res 1993 53: 2399-2409. [Abstract] [PDF]  

Homozygous Loss of the Interferon Genes Defines the Critical Region on 9p That Is Deleted in Lung Cancers

Olufunmilayo I. Olopade, Dorothy L. Buchhagen, Kathleen Malik, Jennifer Sherman, Tsutomu Nobori, Scott Bader, Marion M. Nau, Adi F. Gazdar, John D. Minna, and Manuel O. Diaz
Cancer Res 1993 53: 2410-2415. [Abstract] [PDF]  

Tumor Biology:

Selectively Down-regulated Expression of Major Histocompatibility Complex Class I Alleles in Human Solid Tumors

Zsuzsa Végh, Ping Wang, Farkas Vánky, and Eva Klein
Cancer Res 1993 53: 2416-2420. [Abstract] [PDF]  

Letter to the Editor:

Correspondence re: K. P. Cantor et al., Pesticides and Other Agricultural Risk Factors for Non-Hodgkin's Lymphoma among Men in Iowa and Minnesota, Cancer Res., 52: 2447–2455, 1992

Kenneth P. Cantor, Aaron Blair, Linda M. Brown, Leon F. Burmeister, and George Everett
Cancer Res 1993 53: 2421 [PDF]  

Meeting Report:

Heterocyclic Amines in Cooked Foods: Possible Human Carcinogens

John H. Weisburger
Cancer Res 1993 53: 2422-2424. [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 2425-2426. [PDF]  

Announcements:

Recent Deaths

Cancer Res 1993 53: 2426 [PDF]  

Calendar of Events

Cancer Res 1993 53: 2426-2427. [PDF]  

Erratum:

Distinct Pattern of p53 Mutations in Bladder Cancer: Relationship to Tobacco Usage

Cancer Res 1993 53: 2427 [PDF]  

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