Review:

The Mouse Tumor Biology Database: A Public Resource for Cancer Genetics and Pathology of the Mouse

Dieter Näf, Debra M. Krupke, John P. Sundberg, Janan T. Eppig, and Carol J. Bult
Cancer Res 2002 62: 1235-1240. [Abstract] [Full Text] [PDF]  

Advances in Brief:

Regions of H- and K-Ras That Provide Organ Specificity/Potency in Mammary Cancer Induction

Kwanghee Kim, Mary J. Lindstrom, and Michael N. Gould
Cancer Res 2002 62: 1241-1245. [Abstract] [Full Text] [PDF]  

Isolation of a Novel Gene, CABC1, Encoding a Mitochondrial Protein That Is Highly Homologous to Yeast Activity of bc1 Complex

Megumi Iiizumi, Hirofumi Arakawa, Toshiki Mori, Akikazu Ando, and Yusuke Nakamura
Cancer Res 2002 62: 1246-1250. [Abstract] [Full Text] [PDF]  

Heregulin Induces Expression, ATPase Activity, and Nuclear Localization of G3BP, a Ras Signaling Component, in Human Breast Tumors

Christopher J. Barnes, Feng Li, Mahitosh Mandal, Zhibo Yang, Aysegul A. Sahin, and Rakesh Kumar
Cancer Res 2002 62: 1251-1255. [Abstract] [Full Text] [PDF]  

Clinical Validation of Candidate Genes Associated with Prostate Cancer Progression in the CWR22 Model System using Tissue Microarrays

Spyro Mousses, Lukas Bubendorf, Urs Wagner, Galen Hostetter, Juha Kononen, Robert Cornelison, Natalie Goldberger, Abdel G. Elkahloun, Niels Willi, Pasi Koivisto, William Ferhle, Mark Raffeld, Guito Sauter, and Olli-P Kallioniemi
Cancer Res 2002 62: 1256-1260. [Abstract] [Full Text] [PDF]  

Cellular Localization and Function of Fas Ligand (CD95L) in Tumors

Masayuki Kurooka, Gerard J. Nuovo, Michael A. Caligiuri, and Gary J. Nabel
Cancer Res 2002 62: 1261-1265. [Abstract] [Full Text] [PDF]  

Treatment of Ovarian Cancer with a Tropism Modified Oncolytic Adenovirus

Gerd J. Bauerschmitz, John T. Lam, Anna Kanerva, Kaori Suzuki, Dirk M. Nettelbeck, Igor Dmitriev, Victor Krasnykh, Galina V. Mikheeva, Mack N. Barnes, Ronald D. Alvarez, Peter Dall, Ramon Alemany, David T. Curiel, and Akseli Hemminki
Cancer Res 2002 62: 1266-1270. [Abstract] [Full Text] [PDF]  

The flt-1 Promoter for Transcriptional Targeting of Teratocarcinoma

Gerd J. Bauerschmitz, Dirk M. Nettelbeck, Anna Kanerva, Andrew H. Baker, Akseli Hemminki, Paul N. Reynolds, and David T. Curiel
Cancer Res 2002 62: 1271-1274. [Abstract] [Full Text] [PDF]  

Mouse ING1 Homologue, a Protein Interacting with A1, Enhances Cell Death and Is Inhibited by A1 in Mammary Epithelial Cells

Seckho Ha, Sulra Lee, Myungil Chung, and Yunjaie Choi
Cancer Res 2002 62: 1275-1278. [Abstract] [Full Text] [PDF]  

Gene Conversion Is Strongly Induced in Human Cells by Double-strand Breaks and Is Modulated by the Expression of BCL-x_L

Claudia Wiese, Andrew J. Pierce, Stacey S. Gauny, Maria Jasin, and Amy Kronenberg
Cancer Res 2002 62: 1279-1283. [Abstract] [Full Text] [PDF]  

Mutation Profiling of Mismatch Repair-deficient Colorectal Cancers Using an in Silico Genome Scan to Identify Coding Microsatellites

Jane Park, Doron Betel, Robert Gryfe, Katerina Michalickova, Nando Di Nicola, Steven Gallinger, Christopher W. V. Hogue, and Mark Redston
Cancer Res 2002 62: 1284-1288. [Abstract] [Full Text] [PDF]  

Stanniocalcin 2 Is an Estrogen-responsive Gene Coexpressed with the Estrogen Receptor in Human Breast Cancer

Toula Bouras, Melissa C. Southey, Andy C. Chang, Roger R. Reddel, Dorian Willhite, Richard Glynne, Michael A. Henderson, Jane E. Armes, and Deon J. Venter
Cancer Res 2002 62: 1289-1295. [Abstract] [Full Text] [PDF]  

Complete Genetic Suppression of Polyp Formation and Reduction of CpG-Island Hypermethylation in Apc^Min/+ Dnmt1-Hypomorphic Mice

Cindy A. Eads, Andrea E. Nickel, and Peter W. Laird
Cancer Res 2002 62: 1296-1299. [Abstract] [Full Text] [PDF]  

Differential Gene Expression Profiles of Jnk1- and Jnk2-deficient Murine Fibroblast Cells

Nanyue Chen, Qing-Bai She, Ann M. Bode, and Zigang Dong
Cancer Res 2002 62: 1300-1304. [Abstract] [Full Text] [PDF]  

Expression of p14ARF Overcomes Tumor Resistance to p53

Wenge Lu, Jiayuh Lin, and Jiandong Chen
Cancer Res 2002 62: 1305-1310. [Abstract] [Full Text] [PDF]  

Inhibition of Cancer Cell Growth by BRCA2

Shao-Chun Wang, Ruping Shao, Annie Y. Pao, Su Zhang, Mien-Chie Hung, and Li-Kuo Su
Cancer Res 2002 62: 1311-1314. [Abstract] [Full Text] [PDF]  

Intratumoral Lymphangiogenesis and Lymph Node Metastasis in Head and Neck Cancer

Nigel J. P. Beasley, Remko Prevo, Suneale Banerji, Russell D. Leek, John Moore, Philippe van Trappen, Graham Cox, Adrian L. Harris, and David G. Jackson
Cancer Res 2002 62: 1315-1320. [Abstract] [Full Text] [PDF]  

Identification of a Novel Function for 67-kDa Laminin Receptor: Increase in Laminin Degradation Rate and Release of Motility Fragments

Elena Ardini, Barbara Sporchia, Loredano Pollegioni, Michele Modugno, Cristina Ghirelli, Fabio Castiglioni, Elda Tagliabue, and Sylvie Ménard
Cancer Res 2002 62: 1321-1325. [Abstract] [Full Text] [PDF]  

Relation of Hypoxia-inducible Factor-2 (HIF-2) Expression in Tumor-infiltrative Macrophages to Tumor Angiogenesis and the Oxidative Thymidine Phosphorylase Pathway in Human Breast Cancer

Russell D. Leek, Kate L. Talks, Francesco Pezzella, Helen Turley, Leticia Campo, Nicholas S. Brown, Roy Bicknell, Marian Taylor, Kevin C. Gatter, and Adrian L. Harris
Cancer Res 2002 62: 1326-1329. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Albumin Adducts of Benzene Oxide and 1,4-Benzoquinone as Measures of Human Benzene Metabolism

Stephen M. Rappaport, Suramya Waidyanatha, Qingshan Qu, Roy Shore, Ximei Jin, Beverly Cohen, Lung-Chi Chen, Assieh A. Melikian, Guilan Li, Songnian Yin, Huifang Yan, Bohong Xu, Ruidong Mu, Yuying Li, Xiaoling Zhang, and Keqi Li
Cancer Res 2002 62: 1330-1337. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Suppression of UV Carcinogenesis by Difluoromethylornithine in Nucleotide Excision Repair-deficient Xpa Knockout Mice

Heggert Rebel, Harry van Steeg, Rudolf B. Beems, Ron Schouten, Frank R. de Gruijl, and Carrol Terleth
Cancer Res 2002 62: 1338-1342. [Abstract] [Full Text] [PDF]  

Deficiency of c-Jun-NH₂-terminal Kinase-1 in Mice Enhances Skin Tumor Development by 12-O-Tetradecanoylphorbol-13-Acetate

Qing-Bai She, Nanyue Chen, Ann M. Bode, Richard A. Flavell, and Zigang Dong
Cancer Res 2002 62: 1343-1348. [Abstract] [Full Text] [PDF]  

Defective Repair of 8-Hydroxyguanine in Mitochondria of MCF-7 and MDA-MB-468 Human Breast Cancer Cell Lines

Elizabeth Mambo, Simon G. Nyaga, Vilhelm A. Bohr, and Michele K. Evans
Cancer Res 2002 62: 1349-1355. [Abstract] [Full Text] [PDF]  

Magnetic Field Exposure Increases Cell Proliferation but Does Not Affect Melatonin Levels in the Mammary Gland of Female Sprague Dawley Rats

Maren Fedrowitz, Jürgen Westermann, and Wolfgang Löscher
Cancer Res 2002 62: 1356-1363. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Induction of IgG Subclass Responses in Colorectal Carcinoma Patients Vaccinated with Recombinant Carcinoembryonic Antigen

Gustav J. Ullenhag, Jan-Erik Frödin, Karin Strigård, Håkan Mellstedt, and Carl G. M. Magnusson
Cancer Res 2002 62: 1364-1369. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Toremifene Prevents Prostate Cancer in the Transgenic Adenocarcinoma of Mouse Prostate Model

Sharan Raghow, Massoumeh Z. Hooshdaran, Sanjay Katiyar, and Mitchell S. Steiner
Cancer Res 2002 62: 1370-1376. [Abstract] [Full Text] [PDF]  

Gene-Environment Interaction for the ERCC2 Polymorphisms and Cumulative Cigarette Smoking Exposure in Lung Cancer

Wei Zhou, Geoffrey Liu, David P. Miller, Sally W. Thurston, Li Lian Xu, John C. Wain, Thomas J. Lynch, Li Su, and David C. Christiani
Cancer Res 2002 62: 1377-1381. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Cells Designed to Deliver Anticancer Drugs by Apoptosis

Jianguo Ma, Karin A. Reed, and James M. Gallo
Cancer Res 2002 62: 1382-1387. [Abstract] [Full Text] [PDF]  

Peripheral Benzodiazepine Receptor Ligands Reverse Apoptosis Resistance of Cancer Cells in Vitro and in Vivo

Didier Decaudin, Maria Castedo, Fariba Nemati, Arnaud Beurdeley-Thomas, Gonzague De Pinieux, Antoine Caron, Pierre Pouillart, John Wijdenes, Dany Rouillard, Guido Kroemer, and Marie-France Poupon
Cancer Res 2002 62: 1388-1393. [Abstract] [Full Text] [PDF]  

Nuclear Magnetic Resonance-visible Lipids Induced by Cationic Lipophilic Chemotherapeutic Agents Are Accompanied by Increased Lipid Droplet Formation and Damaged Mitochondria

Edward J. Delikatny, Wendy A. Cooper, Susan Brammah, Nalayini Sathasivam, and Darryl C. Rideout
Cancer Res 2002 62: 1394-1400. [Abstract] [Full Text] [PDF]  

Perifosine, a Novel Alkylphospholipid, Induces p21^WAF1 Expression in Squamous Carcinoma Cells through a p53-independent Pathway, Leading to Loss in Cyclin-dependent Kinase Activity and Cell Cycle Arrest

Vyomesh Patel, Tyler Lahusen, Terence Sy, Edward A. Sausville, J. Sivio Gutkind, and Adrian M. Senderowicz
Cancer Res 2002 62: 1401-1409. [Abstract] [Full Text] [PDF]  

Marked Prevention of Tumor Growth and Metastasis by a Novel Immunosuppressive Agent, FTY720, in Mouse Breast Cancer Models

Haruhito Azuma, Shiro Takahara, Naotsugu Ichimaru, Jing Ding Wang, Yuko Itoh, Yoshinori Otsuki, Junji Morimoto, Ryosuke Fukui, Masaaki Hoshiga, Tadashi Ishihara, Norio Nonomura, Seiichi Suzuki, Akihiko Okuyama, and Yoji Katsuoka
Cancer Res 2002 62: 1410-1419. [Abstract] [Full Text] [PDF]  

Subcellular Localization of NAD(P)H:quinone Oxidoreductase 1 in Human Cancer Cells

Shannon L. Winski, Yiannis Koutalos, David L. Bentley, and David Ross
Cancer Res 2002 62: 1420-1424. [Abstract] [Full Text] [PDF]  

Quantitation of Bystander Effects in Nitroreductase Suicide Gene Therapy Using Three-Dimensional Cell Cultures

William R. Wilson, Susan M. Pullen, Alison Hogg, Nuala A. Helsby, Kevin O. Hicks, and William A. Denny
Cancer Res 2002 62: 1425-1432. [Abstract] [Full Text] [PDF]  

Extracellular Bad Fused to Toxin Transport Domains Induces Apoptosis

Makoto Ichinose, Xiu-Huai Liu, Naoshi Hagihara, and Richard J. Youle
Cancer Res 2002 62: 1433-1438. [Abstract] [Full Text] [PDF]  

Effects of SP500263, a Novel, Potent Antiestrogen, on Breast Cancer Cells and in Xenograft Models

Helen Brady, Sonal Desai, Leah M. Gayo-Fung, Sak Khammungkhune, Jeffrey A. McKie, Eoin O’Leary, Laura Pascasio, May Kung Sutherland, David W. Anderson, Shripad S. Bhagwat, and Bernd Stein
Cancer Res 2002 62: 1439-1442. [Abstract] [Full Text] [PDF]  

Transformed and Tumor-derived Human Cells Exhibit Preferential Sensitivity to the Thiol Antioxidants, N-Acetyl Cysteine and Penicillamine

Pamela A. Havre, Sandra O’Reilly, J. Justin McCormick, and Douglas E. Brash
Cancer Res 2002 62: 1443-1449. [Abstract] [Full Text] [PDF]  

Tumor Cell Apoptosis by Irradiation-induced Nitric Oxide Production in Vascular Endothelium

Masakazu Hirakawa, Masahiro Oike, Kouji Masuda, and Yushi Ito
Cancer Res 2002 62: 1450-1457. [Abstract] [Full Text] [PDF]  

Enhanced Photodynamic Therapy Efficacy with Inducible Suicide Gene Therapy Controlled by the grp Promoter

Marian C. Luna, Xinke Chen, Sam Wong, Janet Tsui, Natalie Rucker, Amy S. Lee, and Charles J. Gomer
Cancer Res 2002 62: 1458-1461. [Abstract] [Full Text] [PDF]  

Immunology:

Combination of T-Cell Therapy and Trigger of Inflammation Induces Remodeling of the Vasculature and Tumor Eradication

Ruth Ganss, Eduard Ryschich, Ernst Klar, Bernd Arnold, and Günter J. Hämmerling
Cancer Res 2002 62: 1462-1470. [Abstract] [Full Text] [PDF]  

Cellular Processing of a Multibranched Lysine Core with Tumor Antigen Peptides and Presentation of Peptide Epitopes Recognized by Cytotoxic T Lymphocytes on Antigen-presenting Cells

Seisuke Ota, Toshiro Ono, Akimichi Morita, Akiko Uenaka, Mine Harada, and Eiichi Nakayama
Cancer Res 2002 62: 1471-1476. [Abstract] [Full Text] [PDF]  

Vaccination with Poly-L-Arginine As Immunostimulant for Peptide Vaccines: Induction of Potent and Long-Lasting T-Cell Responses against Cancer Antigens

Frank Mattner, Julia-Kristina Fleitmann, Karen Lingnau, Walter Schmidt, Alena Egyed, Jörg Fritz, Wolfgang Zauner, Barbara Wittmann, Irmina Gorny, Manfred Berger, Helen Kirlappos, Aleksandr Otava, Max L. Birnstiel, and Michael Buschle
Cancer Res 2002 62: 1477-1480. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Molecular-Cytogenetic Analysis of HER-2/neu Gene in BRCA1-associated Breast Cancers

Tatyana A. Grushko, M. Anne Blackwood, Phil L. Schumm, Fitsum G. Hagos, Moses O. Adeyanju, Michael D. Feldman, Melinda O. Sanders, Barbara L. Weber, and Olufunmilayo I. Olopade
Cancer Res 2002 62: 1481-1488. [Abstract] [Full Text] [PDF]  

A New Player in Oncogenesis: AUF1/hnRNPD Overexpression Leads to Tumorigenesis in Transgenic Mice

Agnàs Gouble, Solàne Grazide, Fabienne Meggetto, Pascale Mercier, Georges Delsol, and Dominique Morello
Cancer Res 2002 62: 1489-1495. [Abstract] [Full Text] [PDF]  

Functional Analysis of 44 Mutant Androgen Receptors from Human Prostate Cancer

Xu-Bao Shi, Ai-Hong Ma, Liang Xia, Hsing-Jien Kung, and Ralph W. de Vere White
Cancer Res 2002 62: 1496-1502. [Abstract] [Full Text] [PDF]  

Aberrant Splicing in Several Human Tumors in the Tumor Suppressor Genes Neurofibromatosis Type 1, Neurofibromatosis Type 2, and Tuberous Sclerosis 2

Dieter Kaufmann, Werner Leistner, Petra Kruse, Oliver Kenner, Sven Hoffmeyer, Christian Hein, Walther Vogel, Ludwine Messiaen, and Britta Bartelt
Cancer Res 2002 62: 1503-1509. [Abstract] [Full Text] [PDF]  

The Tumorigenic Diversity of the Three PLAG Family Members Is Associated with Different DNA Binding Capacities

Karen Hensen, Isabelle C. C. Van Valckenborgh, Koen Kas, Wim J. M. Van de Ven, and Marianne L. Voz
Cancer Res 2002 62: 1510-1517. [Abstract] [Full Text] [PDF]  

Tissue-specific Deletion and Discontinuous Loss of Heterozygosity Are Signatures for the Mutagenic Effects of Ionizing Radiation in Solid Tissues

Olga N. Ponomareva, Jennifer A. Rose, Michael Lasarev, Janet Rasey, and Mitchell S. Turker
Cancer Res 2002 62: 1518-1523. [Abstract] [Full Text] [PDF]  

Deficiency in DNA Polymerase ß Provokes Replication-dependent Apoptosis via DNA Breakage, Bcl-2 Decline and Caspase-3/9 Activation

Kirsten Ochs, Jochen Lips, Simone Profittlich, and Bernd Kaina
Cancer Res 2002 62: 1524-1530. [Abstract] [Full Text] [PDF]  

Allelic Imbalance of 7q32.3-q36.1 during Tumorigenesis in Barrett’s Esophagus

Peter H. J. Riegman, Lawrence J. Burgart, Kenneth K. Wang, Josiane C. J. Wink-Godschalk, Winand N. M. Dinjens, Peter D. Siersema, Hugo W. Tilanus, and Herman van Dekken
Cancer Res 2002 62: 1531-1533. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Real-Time Optical Imaging of Primary Tumor Growth and Multiple Metastatic Events in a Pancreatic Cancer Orthotopic Model

Michael Bouvet, Jinwei Wang, Stephanie R. Nardin, Rounak Nassirpour, Meng Yang, Eugene Baranov, Ping Jiang, A. R. Moossa, and Robert M. Hoffman
Cancer Res 2002 62: 1534-1540. [Abstract] [Full Text] [PDF]  

Identification of Heat Shock Protein 60 as a Molecular Mediator of 3ß1 Integrin Activation

Heba O. Barazi, Longen Zhou, Nancy Smyth Templeton, Henry C. Krutzsch, and David D. Roberts
Cancer Res 2002 62: 1541-1548. [Abstract] [Full Text] [PDF]  

Activation of the Erk Mitogen-activated Protein Kinase Pathway Stimulates Neuroendocrine Differentiation in LNCaP Cells Independently of Cell Cycle Withdrawal and STAT3 Phosphorylation

Jayoung Kim, Rosalyn M. Adam, and Michael R. Freeman
Cancer Res 2002 62: 1549-1554. [Abstract] [Full Text] [PDF]  

Improved Magnetic Resonance Imaging Detection of Prostate Cancer in a Transgenic Mouse Model

Sheng-Kwei Song, Zhican Qu, Emily M. Garabedian, Jeffrey I. Gordon, Jeffrey Milbrandt, and Joseph J. H. Ackerman
Cancer Res 2002 62: 1555-1558. [Abstract] [Full Text] [PDF]  

Nucleophosmin-Anaplastic Lymphoma Kinase (NPM-ALK), a Novel Hsp90-Client Tyrosine Kinase: Down-Regulation of NPM-ALK Expression and Tyrosine Phosphorylation in ALK⁺ CD30⁺ Lymphoma Cells by the Hsp90 Antagonist 17-Allylamino,17-demethoxygeldanamycin

Paolo Bonvini, Tamara Gastaldi, Brunangelo Falini, and Angelo Rosolen
Cancer Res 2002 62: 1559-1566. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Activity Altered the Cell-Surface Carbohydrate Antigens on Colon Cancer Cells and Enhanced Liver Metastasis

Yoshimi Kakiuchi, Shingo Tsuji, Masahiko Tsujii, Hiroaki Murata, Naoki Kawai, Masakazu Yasumaru, Arata Kimura, Masato Komori, Takanobu Irie, Eiji Miyoshi, Yutaka Sasaki, Norio Hayashi, Sunao Kawano, and Masatsugu Hori
Cancer Res 2002 62: 1567-1572. [Abstract] [Full Text] [PDF]  

Meeting Report:

International Consensus Statement on Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis 1

Rosalie E. Ferner and David H. Gutmann
Cancer Res 2002 62: 1573-1577. [Abstract] [Full Text] [PDF]  

Correction:

J. P. Cheadle et al., 62: 363–366, 2002.

Cancer Res 2002 62: 1579 [Full Text] [PDF]  

Erratum:

K. J. Sales et al., 62: 424–432, 2002.

Cancer Res 2002 62: 1579 [Full Text] [PDF]  

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