Advances in Brief:

Mitsutoshi Nakamura, Munehiro Kishi, Toshisuke Sakaki, Hiroyuki Hashimoto, Hiroyuki Nakase, Keiji Shimada, Eiwa Ishida, and Noboru Konishi

Novel Tumor Suppressor Loci on 6q22-23 in Primary Central Nervous System Lymphomas
Cancer Res 2003 63: 737-741. [Abstract] [Full Text] [PDF]  

Steven L. Gibson, Charlotte Y. Dai, Han-Woong Lee, Ronald A. DePinho, Michael S. Gee, William M. F. Lee, Emma E. Furth, Colleen Brensinger, and Greg H. Enders

Inhibition of Colon Tumor Progression and Angiogenesis by the Ink4a/Arf Locus
Cancer Res 2003 63: 742-746. [Abstract] [Full Text] [PDF]  

Yotaro Izumi, Emmanuelle di Tomaso, Andrea Hooper, Peigen Huang, James Huber, Daniel J. Hicklin, Dai Fukumura, Rakesh K. Jain, and Herman D. Suit

Responses to Antiangiogenesis Treatment of Spontaneous Autochthonous Tumors and Their Isografts
Cancer Res 2003 63: 747-751. [Abstract] [Full Text] [PDF]  

Margaret E. McLaughlin and Tyler Jacks

Progesterone Receptor Expression in Neurofibromas
Cancer Res 2003 63: 752-755. [Abstract] [Full Text] [PDF]  

Kapaettu Satyamoorthy, Gang Li, Michelle R. Gerrero, Marcia S. Brose, Patricia Volpe, Barbara L. Weber, Patricia van Belle, David E. Elder, and Meenhard Herlyn

Constitutive Mitogen-activated Protein Kinase Activation in Melanoma Is Mediated by Both BRAF Mutations and Autocrine Growth Factor Stimulation
Cancer Res 2003 63: 756-759. [Abstract] [Full Text] [PDF]  

Xinqiao Zhang, Asha S. Multani, Jain-Hua Zhou, Jerry W. Shay, David McConkey, Li Dong, Chang-Soo Kim, Charles J. Rosser, Sen Pathak, and William F. Benedict

Adenoviral-mediated Retinoblastoma 94 Produces Rapid Telomere Erosion, Chromosomal Crisis, and Caspase-dependent Apoptosis in Bladder Cancer and Immortalized Human Urothelial Cells but not in Normal Urothelial Cells
Cancer Res 2003 63: 760-765. [Abstract] [Full Text] [PDF]  

Nathalie Heuze-Vourc’h, Li Zhu, Kostyantyn Krysan, Raj K. Batra, Sherven Sharma, and Steven M. Dubinett

Abnormal Interleukin 10R Expression Contributes to the Maintenance of Elevated Cyclooxygenase-2 in Non-Small Cell Lung Cancer Cells
Cancer Res 2003 63: 766-770. [Abstract] [Full Text] [PDF]  

Tetsuya Oguri, Shivendra V. Singh, Kaoru Nemoto, and John S. Lazo

The Carcinogen (7R,8S)-Dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene Induces Cdc25B Expression in Human Bronchial and Lung Cancer Cells
Cancer Res 2003 63: 771-775. [Abstract] [Full Text] [PDF]  

Lisa K. Folkes and Peter Wardman

Enhancing the Efficacy of Photodynamic Cancer Therapy by Radicals from Plant Auxin (Indole-3-Acetic Acid)
Cancer Res 2003 63: 776-779. [Abstract] [Full Text] [PDF]  

Amy S. Clark, Kip A. West, Peter M. Blumberg, and Phillip A. Dennis

Altered Protein Kinase C (PKC) Isoforms in Non-Small Cell Lung Cancer Cells: PKC Promotes Cellular Survival and Chemotherapeutic Resistance
Cancer Res 2003 63: 780-786. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Luigi Ricciardiello, Ajay Goel, Vilma Mantovani, Tania Fiorini, Stefania Fossi, Dong K. Chang, Veronica Lunedei, Paolo Pozzato, Rocco M. Zagari, Luca De Luca, Lorenzo Fuccio, Giuseppe N. Martinelli, Enrico Roda, C. Richard Boland, and Franco Bazzoli

Frequent Loss of hMLH1 by Promoter Hypermethylation Leads to Microsatellite Instability in Adenomatous Polyps of Patients with a Single First-Degree Member Affected by Colon Cancer
Cancer Res 2003 63: 787-792. [Abstract] [Full Text] [PDF]  

Silvio De Flora, Roumen M. Balansky, Francesco D’Agostini, Alberto Izzotti, Anna Camoirano, Carlo Bennicelli, Zhongqiu Zhang, Yian Wang, Ronald A. Lubet, and Ming You

Molecular Alterations and Lung Tumors in p53 Mutant Mice Exposed to Cigarette Smoke
Cancer Res 2003 63: 793-800. [Abstract] [Full Text] [PDF]  

Toru Sasaki, Hiroyuki Suzuki, Ken Yagi, Masao Furuhashi, Ryoji Yao, Shinji Susa, Tetsuo Noda, Yoichi Arai, Kohei Miyazono, and Mitsuyasu Kato

Lymphoid Enhancer Factor 1 Makes Cells Resistant to Transforming Growth Factor ß-induced Repression of c-myc
Cancer Res 2003 63: 801-806. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Liu-Ying Luo, Dionyssios Katsaros, Andreas Scorilas, Stefano Fracchioli, Roberto Bellino, Marleen van Gramberen, Henk de Bruijn, Alfthan Henrik, Ulf-Hakan Stenman, Marco Massobrio, Ate G. J. van der Zee, Ignace Vergote, and Eleftherios P. Diamandis

The Serum Concentration of Human Kallikrein 10 Represents a Novel Biomarker for Ovarian Cancer Diagnosis and Prognosis
Cancer Res 2003 63: 807-811. [Abstract] [Full Text] [PDF]  

Endocrinology:

Adam Stevens, Joanne Soden, Paul E. Brenchley, Shirley Ralph, and David W. Ray

Haplotype Analysis of the Polymorphic Human Vascular Endothelial Growth Factor Gene Promoter
Cancer Res 2003 63: 812-816. [Abstract] [Full Text] [PDF]  

Yuan-Jia Chen, Alexander Vortmeyer, Zhengping Zhuang, Steve Huang, and Robert T. Jensen

Loss of Heterozygosity of Chromosome 1q in Gastrinomas: Occurrence and Prognostic Significance
Cancer Res 2003 63: 817-823. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Imad Naasani, Fujiko Oh-hashi, Tomoko Oh-hara, Wan Yong Feng, Jeffrey Johnston, Kenneth Chan, and Takashi Tsuruo

Blocking Telomerase by Dietary Polyphenols Is a Major Mechanism for Limiting the Growth of Human Cancer Cells in Vitro and in Vivo
Cancer Res 2003 63: 824-830. [Abstract] [Full Text] [PDF]  

Liling Yang, Tetsuo Mashima, Shigeo Sato, Mikiko Mochizuki, Hiroshi Sakamoto, Takao Yamori, Tomoko Oh-hara, and Takashi Tsuruo

Predominant Suppression of Apoptosome by Inhibitor of Apoptosis Protein in Non-Small Cell Lung Cancer H460 Cells: Therapeutic Effect of a Novel Polyarginine-conjugated Smac Peptide
Cancer Res 2003 63: 831-837. [Abstract] [Full Text] [PDF]  

Pietro Taverna, Hwa-shin Hwang, Jane E. Schupp, Tomas Radivoyevitch, Nancy Nguyen Session, Guru Reddy, David A. Zarling, and Timothy J. Kinsella

Inhibition of Base Excision Repair Potentiates Iododeoxyuridine-induced Cytotoxicity and Radiosensitization
Cancer Res 2003 63: 838-846. [Abstract] [Full Text] [PDF]  

Akseli Hemminki, Anna Kanerva, Bin Liu, Minghui Wang, Ronald D. Alvarez, Gene P. Siegal, and David T. Curiel

Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral Transgene Expression
Cancer Res 2003 63: 847-853. [Abstract] [Full Text] [PDF]  

Immunology:

Koichi Azuma, Shigeki Shichijo, Yoshiaki Maeda, Tetsuya Nakatsura, Yoichi Nonaka, Teruhiko Fujii, Kenta Koike, and Kyogo Itoh

Mutated p53 Gene Encodes a Nonmutated Epitope Recognized by HLA-B*4601-restricted and Tumor Cell-reactive CTLs at Tumor Site
Cancer Res 2003 63: 854-858. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Maria W. Smith, Zhaoxia N. Yue, Gary K. Geiss, Natalya Y. Sadovnikova, Victoria S. Carter, Loreto Boix, Catherine A. Lazaro, Gary B. Rosenberg, Roger E. Bumgarner, Nelson Fausto, Jordi Bruix, and Michael G. Katze

Identification of Novel Tumor Markers in Hepatitis C Virus-associated Hepatocellular Carcinoma
Cancer Res 2003 63: 859-864. [Abstract] [Full Text] [PDF] Supplementary Data  

Chengtao Her, Xiling Wu, Michael D. Griswold, and Feng Zhou

Human MutS Homologue MSH4 Physically Interacts with von Hippel-Lindau Tumor Suppressor-binding Protein 1
Cancer Res 2003 63: 865-872. [Abstract] [Full Text] [PDF]  

Pang-Dian Fan, Feng Cong, and Stephen P. Goff

Homo- and Hetero-Oligomerization of the c-Abl Kinase and Abelson-Interactor-1
Cancer Res 2003 63: 873-877. [Abstract] [Full Text] [PDF]  

Sai Yendamuri, Tamotsu Kuroki, Francesco Trapasso, Adam C. Henry, Kristoffel R. Dumon, Kay Huebner, Noel N. Williams, Larry R. Kaiser, and Carlo M. Croce

WW Domain Containing Oxidoreductase Gene Expression Is Altered in Non-Small Cell Lung Cancer
Cancer Res 2003 63: 878-881. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Rodolfo Iuliano, Francesco Trapasso, Ilaria Le Pera, Filippo Schepis, Irene Samà, Alessandra Clodomiro, Kristoffel R. Dumon, Massimo Santoro, Lorenzo Chiariotti, Giuseppe Viglietto, and Alfredo Fusco

An Adenovirus Carrying the Rat Protein Tyrosine Phosphatase Suppresses the Growth of Human Thyroid Carcinoma Cell Lines in Vitro and in Vivo
Cancer Res 2003 63: 882-886. [Abstract] [Full Text] [PDF]  

Andrew P. Barbour, Jennifer A. Reeder, Michael D. Walsh, Jonathan Fawcett, Toni M. Antalis, and David C. Gotley

Expression of the CD44v2-10 Isoform Confers a Metastatic Phenotype: Importance of the Heparan Sulfate Attachment Site CD44v3
Cancer Res 2003 63: 887-892. [Abstract] [Full Text] [PDF]  

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