Perspectives in Cancer Research:

Boudewijn J. M. Braakhuis, Maarten P. Tabor, J. Alain Kummer, C. René Leemans, and Ruud H. Brakenhoff

A Genetic Explanation of Slaughter’s Concept of Field Cancerization: Evidence and Clinical Implications
Cancer Res 2003 63: 1727-1730. [Abstract] [Full Text] [PDF]  

Advances in Brief:

Sucharita Bandyopadhyay, Sudha K. Pai, Steven C. Gross, Shigeru Hirota, Sadahiro Hosobe, Kunio Miura, Ken Saito, Therese Commes, Sunao Hayashi, Misako Watabe, and Kounosuke Watabe

The Drg-1 Gene Suppresses Tumor Metastasis in Prostate Cancer
Cancer Res 2003 63: 1731-1736. [Abstract] [Full Text] [PDF]  

Sofie Svensson, Kristina Nilsson, Anita Ringberg, and Göran Landberg

Invade or Proliferate? Two Contrasting Events in Malignant Behavior Governed by p16^INK4a and an Intact Rb Pathway Illustrated by a Model System of Basal Cell Carcinoma
Cancer Res 2003 63: 1737-1742. [Abstract] [Full Text] [PDF]  

Charlotta Lindvall, Mi Hou, Toshi Komurasaki, Chengyun Zheng, Marie Henriksson, John M. Sedivy, Magnus Björkholm, Bin Tean Teh, Magnus Nordenskjöld, and Dawei Xu

Molecular Characterization of Human Telomerase Reverse Transcriptase-immortalized Human Fibroblasts by Gene Expression Profiling: Activation of the Epiregulin Gene
Cancer Res 2003 63: 1743-1747. [Abstract] [Full Text] [PDF] Supplementary Data  

N. Shane Cutler, Ramona Graves-Deal, Bonnie J. LaFleur, Zhenqiang Gao, Bruce M. Boman, Robert H. Whitehead, Erin Terry, Jason D. Morrow, and Robert J. Coffey

Stromal Production of Prostacyclin Confers an Antiapoptotic Effect to Colonic Epithelial Cells
Cancer Res 2003 63: 1748-1751. [Abstract] [Full Text] [PDF]  

Volker Mai, Lisa H. Colbert, David Berrigan, Susan N. Perkins, Ruth Pfeiffer, Jackie A. Lavigne, Elaine Lanza, Diana C. Haines, Arthur Schatzkin, and Stephen D. Hursting

Calorie Restriction and Diet Composition Modulate Spontaneous Intestinal Tumorigenesis in Apc^Min Mice through Different Mechanisms
Cancer Res 2003 63: 1752-1755. [Abstract] [Full Text] [PDF]  

Ana Contente, Hans Zischler, Almuth Einspanier, and Matthias Dobbelstein

A Promoter that Acquired p53 Responsiveness During Primate Evolution
Cancer Res 2003 63: 1756-1758. [Abstract] [Full Text] [PDF]  

Gary A. Ulaner, Hsuan-Ying Huang, Jesse Otero, Zhiquan Zhao, Leah Ben-Porat, Jaya M. Satagopan, Richard Gorlick, Paul Meyers, John H. Healey, Andrew G. Huvos, Andrew R. Hoffman, and Marc Ladanyi

Absence of a Telomere Maintenance Mechanism as a Favorable Prognostic Factor in Patients with Osteosarcoma
Cancer Res 2003 63: 1759-1763. [Abstract] [Full Text] [PDF]  

Helen J. Knowles, Raju R. Raval, Adrian L. Harris, and Peter J. Ratcliffe

Effect of Ascorbate on the Activity of Hypoxia-inducible Factor in Cancer Cells
Cancer Res 2003 63: 1764-1768. [Abstract] [Full Text] [PDF]  

Sean P. Cleary, William Zhang, Nando Di Nicola, Melyssa Aronson, Jennifer Aube, Amanda Steinman, Riad Haddad, Mark Redston, Steven Gallinger, Steven A. Narod, and Robert Gryfe

Heterozygosity for the BLM^Ash Mutation and Cancer Risk
Cancer Res 2003 63: 1769-1771. [Abstract] [Full Text] [PDF]  

Ingo Müller, Stefan M. Pfister, Ulrike Grohs, Janine Zweigner, Rupert Handgretinger, Dietrich Niethammer, and Gernot Bruchelt

Receptor Activator of Nuclear Factor B Ligand Plays a Nonredundant Role in Doxorubicin-induced Apoptosis
Cancer Res 2003 63: 1772-1775. [Abstract] [Full Text] [PDF]  

Petr Ilinski, Barry Lai, Zhonghou Cai, Wenbing Yun, Daniel Legnini, Teresa Talarico, Marian Cholewa, Lorraine K. Webster, Glen B. Deacon, Silvina Rainone, Don R. Phillips, and Anton P. J. Stampfl

The Direct Mapping of the Uptake of Platinum Anticancer Agents in Individual Human Ovarian Adenocarcinoma Cells Using a Hard X-ray Microprobe
Cancer Res 2003 63: 1776-1779. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Gary D. Luker, Vijay Sharma, Christina M. Pica, Julie L. Prior, Wei Li, and David Piwnica-Worms

Molecular Imaging of Protein-Protein Interactions: Controlled Expression of p53 and Large T-Antigen Fusion Proteins in Vivo
Cancer Res 2003 63: 1780-1788. [Abstract] [Full Text] [PDF]  

Pritam K. Sengupta, Erin M. Smith, Kwonseop Kim, Mary Jo Murnane, and Barbara D. Smith

DNA Hypermethylation Near the Transcription Start Site of Collagen 2(I) Gene Occurs in Both Cancer Cell Lines and Primary Colorectal Cancers
Cancer Res 2003 63: 1789-1797. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Nicola Brady, Terry J. Gaymes, Manyee Cheung, Ghulam J. Mufti, and Feyruz V. Rassool

Increased Error-prone NHEJ Activity in Myeloid Leukemias Is Associated with DNA Damage at Sites that Recruit Key Nonhomologous End-Joining Proteins
Cancer Res 2003 63: 1798-1805. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

David A. Bellnier, William R. Greco, Gregory M. Loewen, Hector Nava, Allan R. Oseroff, Ravindra K. Pandey, Takaaki Tsuchida, and Thomas J. Dougherty

Population Pharmacokinetics of the Photodynamic Therapy Agent 2-[1-Hexyloxyethyl]-2-devinyl Pyropheophorbide-a in Cancer Patients
Cancer Res 2003 63: 1806-1813. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Mercedes Robledo, Laura Gil, Marina Pollán, Arancha Cebrián, Sergio Ruíz, Marta Azañedo, Javier Benitez, Javier Menárguez, and José M. Rojas

Polymorphisms G691S/S904S of RET as Genetic Modifiers of MEN 2A
Cancer Res 2003 63: 1814-1817. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Theodossis Theodossiou, John S. Hothersall, Elizabeth A. Woods, Klaus Okkenhaug, Jake Jacobson, and Alexander J. MacRobert

Firefly Luciferin-activated Rose Bengal: In Vitro Photodynamic Therapy by Intracellular Chemiluminescence in Transgenic NIH 3T3 Cells
Cancer Res 2003 63: 1818-1821. [Abstract] [Full Text] [PDF]  

Chunrong Yu, Mohamed Rahmani, Yun Dai, Daniel Conrad, Geoffrey Krystal, Paul Dent, and Steven Grant

The Lethal Effects of Pharmacological Cyclin-dependent Kinase Inhibitors in Human Leukemia Cells Proceed through a Phosphatidylinositol 3-Kinase/Akt-dependent Process
Cancer Res 2003 63: 1822-1833. [Abstract] [Full Text] [PDF]  

Tie Fu Liu, Kimberley A. Cohen, Jason G. Ramage, Mark C. Willingham, Andrew M. Thorburn, and Arthur E. Frankel

A Diphtheria Toxin-Epidermal Growth Factor Fusion Protein Is Cytotoxic to Human Glioblastoma Multiforme Cells
Cancer Res 2003 63: 1834-1837. [Abstract] [Full Text] [PDF]  

Frank Loganzo, Carolyn M. Discafani, Tami Annable, Carl Beyer, Sylvia Musto, Malathi Hari, Xingzhi Tan, Carolyn Hardy, Richard Hernandez, Michelle Baxter, Thiruvikraman Singanallore, Gulnaz Khafizova, Marianne S. Poruchynsky, Tito Fojo, James A. Nieman, Semiramis Ayral-Kaloustian, Arie Zask, Raymond J. Andersen, and Lee M. Greenberger

HTI-286, a Synthetic Analogue of the Tripeptide Hemiasterlin, Is a Potent Antimicrotubule Agent that Circumvents P-Glycoprotein-mediated Resistance in Vitro and in Vivo
Cancer Res 2003 63: 1838-1845. [Abstract] [Full Text] [PDF]  

Irmgard Tegeder, Sabine Grösch, Achim Schmidtko, Annett Häussler, Helmut Schmidt, Ellen Niederberger, Klaus Scholich, and Gerd Geisslinger

G Protein-independent G₁ Cell Cycle Block and Apoptosis with Morphine in Adenocarcinoma Cells: Involvement of p53 Phosphorylation
Cancer Res 2003 63: 1846-1852. [Abstract] [Full Text] [PDF]  

Guo-Qiang Chen, Li Zhou, Miroslav Styblo, Felecia Walton, Yongkui Jing, Rona Weinberg, Zhu Chen, and Samuel Waxman

Methylated Metabolites of Arsenic Trioxide Are More Potent Than Arsenic Trioxide as Apoptotic but not Differentiation Inducers in Leukemia and Lymphoma Cells
Cancer Res 2003 63: 1853-1859. [Abstract] [Full Text] [PDF]  

Immunology:

James J. Kobie, Rita S. Wu, Robert A. Kurt, Sunming Lou, Miranda K. Adelman, Luke J. Whitesell, Lalitha V. Ramanathapuram, Carlos L. Arteaga, and Emmanuel T. Akporiaye

Transforming Growth Factor ß Inhibits the Antigen-Presenting Functions and Antitumor Activity of Dendritic Cell Vaccines
Cancer Res 2003 63: 1860-1864. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Soumen Khatua, Katia M. Peterson, Kevin M. Brown, Christopher Lawlor, Maria R. Santi, Bonnie LaFleur, Devin Dressman, Dietrich A. Stephan, and Tobey J. MacDonald

Overexpression of the EGFR/FKBP12/HIF-2 Pathway Identified in Childhood Astrocytomas by Angiogenesis Gene Profiling
Cancer Res 2003 63: 1865-1870. [Abstract] [Full Text] [PDF] Supplementary Data  

Manuela Gariboldi, Bernard Peissel, Alessandra Fabbri, Anna Saran, Daniela Zaffaroni, F. Stefania Falvella, Monica Spinola, Jun-ichi Tanuma, Simonetta Pazzaglia, Maria Teresa Mancuso, Andrea Maurichi, Cesare Bartoli, Sule Cataltepe, Gary A. Silverman, Silvana Pilotti, Yoshihide Hayashizaki, Yasushi Okazaki, and Tommaso A. Dragani

SCCA2-like Serpins Mediate Genetic Predisposition to Skin Tumors
Cancer Res 2003 63: 1871-1875. [Abstract] [Full Text] [PDF]  

Fumiko Saito-Ohara, Issei Imoto, Jun Inoue, Hajime Hosoi, Akira Nakagawara, Tohru Sugimoto, and Johji Inazawa

PPM1D Is a Potential Target for 17q Gain in Neuroblastoma
Cancer Res 2003 63: 1876-1883. [Abstract] [Full Text] [PDF]  

Bret Taback, Armando E. Giuliano, Nora M. Hansen, Frederick R. Singer, Sherry Shu, and Dave S. B. Hoon

Detection of Tumor-Specific Genetic Alterations in Bone Marrow from Early-Stage Breast Cancer Patients
Cancer Res 2003 63: 1884-1887. [Abstract] [Full Text] [PDF]  

Igor Kuzmin, Limin Liu, Reinhard Dammann, Laura Geil, Eric J. Stanbridge, Sharon P. Wilczynski, Michael I. Lerman, and Gerd P. Pfeifer

Inactivation of RAS Association Domain Family 1A Gene in Cervical Carcinomas and the Role of Human Papillomavirus Infection
Cancer Res 2003 63: 1888-1893. [Abstract] [Full Text] [PDF]  

Hong-Xu Liu, Xiao-Lei Zhou, Tao Liu, Barbro Werelius, Gudrun Lindmark, Niklas Dahl, and Annika Lindblom

The Role of hMLH3 in Familial Colorectal Cancer
Cancer Res 2003 63: 1894-1899. [Abstract] [Full Text] [PDF]  

Thanh H. Vu, Nguyen V. Chuyen, Tao Li, and Andrew R. Hoffman

Loss of Imprinting of IGF2 Sense and Antisense Transcripts in Wilms’ Tumor
Cancer Res 2003 63: 1900-1905. [Abstract] [Full Text] [PDF]  

Louise R. Howe, Osamu Watanabe, James Leonard, and Anthony M. C. Brown

Twist Is Up-Regulated in Response to Wnt1 and Inhibits Mouse Mammary Cell Differentiation
Cancer Res 2003 63: 1906-1913. [Abstract] [Full Text] [PDF]  

Brittney-Shea Herbert, Virginia P. Pearce, Linda S. Hynan, Denise M. LaRue, Woodring E. Wright, Levy Kopelovich, and Jerry W. Shay

A Peroxisome Proliferator-activated Receptor- Agonist and the p53 Rescue Drug CP-31398 Inhibit the Spontaneous Immortalization of Breast Epithelial Cells
Cancer Res 2003 63: 1914-1919. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Sanna-Mari Maula, Marjaana Luukkaa, Reidar Grénman, David Jackson, Sirpa Jalkanen, and Raija Ristamäki

Intratumoral Lymphatics Are Essential for the Metastatic Spread and Prognosis in Squamous Cell Carcinomas of the Head and Neck Region
Cancer Res 2003 63: 1920-1926. [Abstract] [Full Text] [PDF]  

Yan Chen, Christine Miller, Rebecca Mosher, Xumei Zhao, Jim Deeds, Mike Morrissey, Barb Bryant, David Yang, Ron Meyer, Frank Cronin, Bobbie S. Gostout, Karen Smith-McCune, and Robert Schlegel

Identification of Cervical Cancer Markers by cDNA and Tissue Microarrays
Cancer Res 2003 63: 1927-1935. [Abstract] [Full Text] [PDF]  

Alexander Petrovsky, Eyk Schellenberger, Lee Josephson, Ralph Weissleder, and Alexei Bogdanov, Jr.

Near-Infrared Fluorescent Imaging of Tumor Apoptosis
Cancer Res 2003 63: 1936-1942. [Abstract] [Full Text] [PDF]  

Nina Pedersen, Shila Mortensen, Susanne B. Sørensen, Mikkel W. Pedersen, Klaus Rieneck, Lone F. Bovin, and Hans Skovgaard Poulsen

Transcriptional Gene Expression Profiling of Small Cell Lung Cancer Cells
Cancer Res 2003 63: 1943-1953. [Abstract] [Full Text] [PDF]  

Ethan D. Emberley, Yulian Niu, Etienne Leygue, Ladislav Tomes, R. Daniel Gietz, Leigh C. Murphy, and Peter H. Watson

Psoriasin Interacts with Jab1 and Influences Breast Cancer Progression
Cancer Res 2003 63: 1954-1961. [Abstract] [Full Text] [PDF]  

Yukihiko Sonoda, Masayuki Kanamori, Dennis F. Deen, Shi-Yuan Cheng, Mitchel S. Berger, and Russell O. Pieper

Overexpression of Vascular Endothelial Growth Factor Isoforms Drives Oxygenation and Growth but not Progression to Glioblastoma Multiforme in a Human Model of Gliomagenesis
Cancer Res 2003 63: 1962-1968. [Abstract] [Full Text] [PDF]  

Simone Barbero, Rudy Bonavia, Adriana Bajetto, Carola Porcile, Paolo Pirani, Jean Louis Ravetti, Gian Luigi Zona, Renato Spaziante, Tullio Florio, and Gennaro Schettini

Stromal Cell-derived Factor 1 Stimulates Human Glioblastoma Cell Growth through the Activation of Both Extracellular Signal-regulated Kinases 1/2 and Akt
Cancer Res 2003 63: 1969-1974. [Abstract] [Full Text] [PDF]  

Robert E. Bakin, Daniel Gioeli, Eric A. Bissonette, and Michael J. Weber

Attenuation of Ras Signaling Restores Androgen Sensitivity to Hormone-refractory C4-2 Prostate Cancer Cells
Cancer Res 2003 63: 1975-1980. [Abstract] [Full Text] [PDF]  

Robert E. Bakin, Daniel Gioeli, Robert A. Sikes, Eric A. Bissonette, and Michael J. Weber

Constitutive Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway Promotes Androgen Hypersensitivity in LNCaP Prostate Cancer Cells
Cancer Res 2003 63: 1981-1989. [Abstract] [Full Text] [PDF]  

Kevin Camphausen, Marsha A. Moses, Cynthia Ménard, Mary Sproull, Wolf-Dietrich Beecken, Judah Folkman, and Michael S. O’Reilly

Radiation Abscopal Antitumor Effect Is Mediated through p53
Cancer Res 2003 63: 1990-1993. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Wim Jongmans, Dorien M. Tiemessen, Egbert Oosterwijk, and Peter F. A. Mulders

Correspondence re: Y. S. Haviv, J. L. Blackwell, A. Kanerva, P. Nagi, V. Krasnykh, I. Dmitriev, M. Wang, S. Naito, X. Lei, A. Hemminki, D. Carey, and D. T. Curiel, Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors. Cancer Res., 62: 4273–4281, 2002.
Cancer Res 2003 63: 1994-1995. [Full Text] [PDF]  

Correction:

Cancer Res 2003 63: 1997. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.