Advances in Brief:

Robert R. Langley, Dominic Fan, Rachel Z. Tsan, Robert Rebhun, Junqin He, Sun-Jin Kim, and Isaiah J. Fidler

Activation of the Platelet-Derived Growth Factor-Receptor Enhances Survival of Murine Bone Endothelial Cells
Cancer Res 2004 64: 3727-3730. [Abstract] [Full Text] [PDF]  

Ricky T. Tong, Yves Boucher, Sergey V. Kozin, Frank Winkler, Daniel J. Hicklin, and Rakesh K. Jain

Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors
Cancer Res 2004 64: 3731-3736. [Abstract] [Full Text] [PDF]  

Yulong He, Iiro Rajantie, Maritta Ilmonen, Taija Makinen, Marika J. Karkkainen, Paula Haiko, Petri Salven, and Kari Alitalo

Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic Metastasis
Cancer Res 2004 64: 3737-3740. [Abstract] [Full Text] [PDF]  

Itaru Sonoda, Issei Imoto, Jun Inoue, Tatsuhiro Shibata, Yutaka Shimada, Koei Chin, Masayuki Imamura, Teruo Amagasa, Joe W. Gray, Setsuo Hirohashi, and Johji Inazawa

Frequent Silencing of Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B) Expression by Genetic and Epigenetic Mechanisms in Esophageal Squamous Cell Carcinoma
Cancer Res 2004 64: 3741-3747. [Abstract] [Full Text] [PDF]  

Christopher J. Bakkenist, Rachid Drissi, Jing Wu, Michael B. Kastan, and Jeffrey S. Dome

Disappearance of the Telomere Dysfunction-Induced Stress Response in Fully Senescent Cells
Cancer Res 2004 64: 3748-3752. [Abstract] [Full Text] [PDF]  

Junichi Takamizawa, Hiroyuki Konishi, Kiyoshi Yanagisawa, Shuta Tomida, Hirotaka Osada, Hideki Endoh, Tomoko Harano, Yasushi Yatabe, Masato Nagino, Yuji Nimura, Tetsuya Mitsudomi, and Takashi Takahashi

Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival
Cancer Res 2004 64: 3753-3756. [Abstract] [Full Text] [PDF]  

Narayan Shivapurkar, Takao Takahashi, Jyotsna Reddy, Yingye Zheng, Victor Stastny, Robert Collins, Shinichi Toyooka, Makato Suzuki, Gunjan Parikh, Sheryl Asplund, Steven H. Kroft, Charles Timmons, Robert W. McKenna, Ziding Feng, and Adi F. Gazdar

Presence of Simian Virus 40 DNA Sequences in Human Lymphoid and Hematopoietic Malignancies and Their Relationship to Aberrant Promoter Methylation of Multiple Genes
Cancer Res 2004 64: 3757-3760. [Abstract] [Full Text] [PDF]  

Jennifer D. Davidson, Liandong Ma, Michael Flagella, Sandaruwan Geeganage, Lawrence M. Gelbert, and Christopher A. Slapak

An Increase in the Expression of Ribonucleotide Reductase Large Subunit 1 Is Associated with Gemcitabine Resistance in Non-Small Cell Lung Cancer Cell Lines
Cancer Res 2004 64: 3761-3766. [Abstract] [Full Text] [PDF]  

Cristiana Perrotta, Sestina Falcone, Annalisa Capobianco, Annalisa Camporeale, Clara Sciorati, Clara De Palma, Addolorata Pisconti, Patrizia Rovere-Querini, Matteo Bellone, Angelo A. Manfredi, and Emilio Clementi

Nitric Oxide Confers Therapeutic Activity to Dendritic Cells in a Mouse Model of Melanoma
Cancer Res 2004 64: 3767-3771. [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Mari Kielosto, Pirjo Nummela, Riikka Katainen, Virna Leaner, Michael J. Birrer, and Erkki Hölttä

Reversible Regulation of the Transformed Phenotype of Ornithine Decarboxylase- and Ras-Overexpressing Cells by Dominant-Negative Mutants of c-Jun
Cancer Res 2004 64: 3772-3779. [Abstract] [Full Text] [PDF]  

Volkert B. Wreesmann, Elizabeth M. Sieczka, Nicholas D. Socci, Michael Hezel, Thomas J. Belbin, Geoffrey Childs, Snehal G. Patel, Kepal N. Patel, Giovanni Tallini, Michael Prystowsky, Ashok R. Shaha, Dennis Kraus, Jatin P. Shah, Pulivarthi H. Rao, Ronald Ghossein, and Bhuvanesh Singh

Genome-Wide Profiling of Papillary Thyroid Cancer Identifies MUC1 as an Independent Prognostic Marker
Cancer Res 2004 64: 3780-3789. [Abstract] [Full Text] [PDF]  

Nebojsa Mirkovic, Marc A. Marti-Renom, Barbara L. Weber, Andrej Sali, and Alvaro N. A. Monteiro

Structure-Based Assessment of Missense Mutations in Human BRCA1: Implications for Breast and Ovarian Cancer Predisposition
Cancer Res 2004 64: 3790-3797. [Abstract] [Full Text] [PDF] Supplementary Data  

Simonetta Pazzaglia, Mariateresa Mancuso, Mirella Tanori, Michael J. Atkinson, Paola Merola, Simonetta Rebessi, Vincenzo Di Majo, Vincenzo Covelli, Heidi Hahn, and Anna Saran

Modulation of Patched-Associated Susceptibility to Radiation Induced Tumorigenesis by Genetic Background
Cancer Res 2004 64: 3798-3806. [Abstract] [Full Text] [PDF]  

Martin Widschwendter, Kimberly D. Siegmund, Hannes M. Müller, Heidi Fiegl, Christian Marth, Elisabeth Müller-Holzner, Peter A. Jones, and Peter W. Laird

Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen
Cancer Res 2004 64: 3807-3813. [Abstract] [Full Text] [PDF] Supplementary Data  

Mark A. Rubin, Sooryanarayana Varambally, Rameen Beroukhim, Scott A. Tomlins, Daniel R. Rhodes, Pamela L. Paris, Matthias D. Hofer, Martina Storz-Schweizer, Rainer Kuefer, Jonathan A. Fletcher, Bae-Li Hsi, Jennifier A. Byrne, Kenneth J. Pienta, Colin Collins, William R. Sellers, and Arul M. Chinnaiyan

Overexpression, Amplification, and Androgen Regulation of TPD52 in Prostate Cancer
Cancer Res 2004 64: 3814-3822. [Abstract] [Full Text] [PDF]  

Donata Vitagliano, Francesca Carlomagno, Maria Letizia Motti, Giuseppe Viglietto, Yuri E. Nikiforov, Marina N. Nikiforova, Jerome M. Hershman, Anderson J. Ryan, Alfredo Fusco, Rosa Marina Melillo, and Massimo Santoro

Regulation of p27Kip1 Protein Levels Contributes to Mitogenic Effects of the RET/PTC Kinase in Thyroid Carcinoma Cells
Cancer Res 2004 64: 3823-3829. [Abstract] [Full Text] [PDF]  

Poppy Fotiadou, Octavian Henegariu, and Joann B. Sweasy

DNA Polymerase ß Interacts with TRF2 and Induces Telomere Dysfunction in a Murine Mammary Cell Line
Cancer Res 2004 64: 3830-3837. [Abstract] [Full Text] [PDF]  

Genshi Ito, Mika Uchiyama, Masashi Kondo, Shoichi Mori, Noriyasu Usami, Osamu Maeda, Tsutomu Kawabe, Yoshinori Hasegawa, Kaoru Shimokata, and Yoshitaka Sekido

Krüppel-Like Factor 6 Is Frequently Down-Regulated and Induces Apoptosis in Non-Small Cell Lung Cancer Cells
Cancer Res 2004 64: 3838-3843. [Abstract] [Full Text] [PDF]  

Leah C. Pulling, Brian R. Vuillemenot, Julie A. Hutt, Theodora R. Devereux, and Steven A. Belinsky

Aberrant Promoter Hypermethylation of the Death-Associated Protein Kinase Gene Is Early and Frequent in Murine Lung Tumors Induced by Cigarette Smoke and Tobacco Carcinogens
Cancer Res 2004 64: 3844-3848. [Abstract] [Full Text] [PDF]  

Connie Cheung, Taro E. Akiyama, Jerrold M. Ward, Christopher J. Nicol, Lionel Feigenbaum, Charles Vinson, and Frank J. Gonzalez

Diminished Hepatocellular Proliferation in Mice Humanized for the Nuclear Receptor Peroxisome Proliferator-Activated Receptor
Cancer Res 2004 64: 3849-3854. [Abstract] [Full Text] [PDF]  

Yong-Yeon Cho, Ann M. Bode, Hideya Mizuno, Bu Young Choi, Hong Seok Choi, and Zigang Dong

A Novel Role for Mixed-Lineage Kinase-Like Mitogen-Activated Protein Triple Kinase in Neoplastic Cell Transformation and Tumor Development
Cancer Res 2004 64: 3855-3864. [Abstract] [Full Text] [PDF]  

David F. Lee, Regen Drouin, Photini Pitsikas, and Andrew J. Rainbow

Detection of an Involvement of the Human Mismatch Repair Genes hMLH1 and hMSH2 in Nucleotide Excision Repair Is Dependent on UVC Fluence to Cells
Cancer Res 2004 64: 3865-3870. [Abstract] [Full Text] [PDF]  

Clare Stirzaker, Jenny Z. Song, Ben Davidson, and Susan J. Clark

Transcriptional Gene Silencing Promotes DNA Hypermethylation through a Sequential Change in Chromatin Modifications in Cancer Cells
Cancer Res 2004 64: 3871-3877. [Abstract] [Full Text] [PDF]  

Nicolas Wentzensen, Svetlana Vinokurova, and Magnus von Knebel Doeberitz

Systematic Review of Genomic Integration Sites of Human Papillomavirus Genomes in Epithelial Dysplasia and Invasive Cancer of the Female Lower Genital Tract
Cancer Res 2004 64: 3878-3884. [Abstract] [Full Text] [PDF]  

Cell and Tumor Biology:

Sharon Benzeno, Goutham Narla, Jorge Allina, George Z. Cheng, Helen L. Reeves, Michaela S. Banck, Joseph A. Odin, J. Alan Diehl, Doris Germain, and Scott L. Friedman

Cyclin-Dependent Kinase Inhibition by the KLF6 Tumor Suppressor Protein through Interaction with Cyclin D1
Cancer Res 2004 64: 3885-3891. [Abstract] [Full Text] [PDF]  

Rebecca L. Elstrom, Daniel E. Bauer, Monica Buzzai, Robyn Karnauskas, Marian H. Harris, David R. Plas, Hongming Zhuang, Ryan M. Cinalli, Abass Alavi, Charles M. Rudin, and Craig B. Thompson

Akt Stimulates Aerobic Glycolysis in Cancer Cells
Cancer Res 2004 64: 3892-3899. [Abstract] [Full Text] [PDF]  

Tina Pohle, Stephanie Brändlein, Nele Ruoff, Hans Konrad Müller-Hermelink, and H. Peter Vollmers

Lipoptosis: Tumor-Specific Cell Death by Antibody-Induced Intracellular Lipid Accumulation
Cancer Res 2004 64: 3900-3906. [Abstract] [Full Text] [PDF]  

Sanjay Jain, Mark A. Watson, Mary K. DeBenedetti, Yuji Hiraki, Jeffrey F. Moley, and Jeffrey Milbrandt

Expression Profiles Provide Insights into Early Malignant Potential and Skeletal Abnormalities in Multiple Endocrine Neoplasia Type 2B Syndrome Tumors
Cancer Res 2004 64: 3907-3913. [Abstract] [Full Text] [PDF] Supplementary Data  

Martin G. Sauer, Marna E. Ericson, Brenda J. Weigel, Michael J. Herron, Angela Panoskaltsis-Mortari, Betsy T. Kren, Bruce L. Levine, Jon S. Serody, Carl H. June, Patricia A. Taylor, and Bruce R. Blazar

A Novel System for Simultaneous in Vivo Tracking and Biological Assessment of Leukemia Cells and ex Vivo Generated Leukemia-Reactive Cytotoxic T Cells
Cancer Res 2004 64: 3914-3921. [Abstract] [Full Text] [PDF]  

Alexandre Nesterov, Malti Nikrad, Thomas Johnson, and Andrew S. Kraft

Oncogenic Ras Sensitizes Normal Human Cells to Tumor Necrosis Factor--Related Apoptosis-Inducing Ligand-Induced Apoptosis
Cancer Res 2004 64: 3922-3927. [Abstract] [Full Text] [PDF]  

Xiaotong He, Paul E. C. Brenchley, Gordon C. Jayson, Lynne Hampson, John Davies, and Ian N. Hampson

Hypoxia Increases Heparanase-Dependent Tumor Cell Invasion, Which Can Be Inhibited by Antiheparanase Antibodies
Cancer Res 2004 64: 3928-3933. [Abstract] [Full Text] [PDF]  

Marlene R. D. Quadros, Francesca Peruzzi, Csaba Kari, and Ulrich Rodeck

Complex Regulation of Signal Transducers and Activators of Transcription 3 Activation in Normal and Malignant Keratinocytes
Cancer Res 2004 64: 3934-3939. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

H. Irene Wu, James A. Brown, Mary J. Dorie, Laura Lazzeroni, and J. Martin Brown

Genome-Wide Identification of Genes Conferring Resistance to the Anticancer Agents Cisplatin, Oxaliplatin, and Mitomycin C
Cancer Res 2004 64: 3940-3948. [Abstract] [Full Text] [PDF]  

Wei Chen, Jeongwu Lee, Steve Y. Cho, and Howard A. Fine

Proteasome-Mediated Destruction of the Cyclin A/Cyclin-Dependent Kinase 2 Complex Suppresses Tumor Cell Growth in Vitro and in Vivo
Cancer Res 2004 64: 3949-3957. [Abstract] [Full Text] [PDF]  

Sridhar K. Rabindran, Carolyn M. Discafani, Edward C. Rosfjord, Michelle Baxter, M. Brawner Floyd, Jonathan Golas, William A. Hallett, Bernard D. Johnson, Ramaswamy Nilakantan, Elsebe Overbeek, Marvin F. Reich, Ru Shen, Xiaoqing Shi, Hwei-Ru Tsou, Yu-Fen Wang, and Allan Wissner

Antitumor Activity of HKI-272, an Orally Active, Irreversible Inhibitor of the HER-2 Tyrosine Kinase
Cancer Res 2004 64: 3958-3965. [Abstract] [Full Text] [PDF]  

Atsuko Deguchi, W. Joseph Thompson, and I. Bernard Weinstein

Activation of Protein Kinase G Is Sufficient to Induce Apoptosis and Inhibit Cell Migration in Colon Cancer Cells
Cancer Res 2004 64: 3966-3973. [Abstract] [Full Text] [PDF]  

Veeraswamy Manne, Francis Y. F. Lee, David K. Bol, Johnni Gullo-Brown, Craig R. Fairchild, Louis J. Lombardo, Richard A. Smykla, Gregory D. Vite, Mei-Li D. Wen, Chiang Yu, Tai Wai Wong, and John T. Hunt

Apoptotic and Cytostatic Farnesyltransferase Inhibitors Have Distinct Pharmacology and Efficacy Profiles in Tumor Models
Cancer Res 2004 64: 3974-3980. [Abstract] [Full Text] [PDF]  

Rita Nahta, Takeshi Takahashi, Naoto T. Ueno, Mien-Chie Hung, and Francisco J. Esteva

P27^kip1 Down-Regulation Is Associated with Trastuzumab Resistance in Breast Cancer Cells
Cancer Res 2004 64: 3981-3986. [Abstract] [Full Text] [PDF]  

Mark S. Duxbury, Hiromichi Ito, Eric Benoit, Talat Waseem, Stanley W. Ashley, and Edward E. Whang

A Novel Role for Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 as a Determinant of Gemcitabine Chemoresistance in Pancreatic Adenocarcinoma Cells
Cancer Res 2004 64: 3987-3993. [Abstract] [Full Text] [PDF]  

Urban Emmenegger, Shan Man, Yuval Shaked, Giulio Francia, John W. Wong, Daniel J. Hicklin, and Robert S. Kerbel

A Comparative Analysis of Low-Dose Metronomic Cyclophosphamide Reveals Absent or Low-Grade Toxicity on Tissues Highly Sensitive to the Toxic Effects of Maximum Tolerated Dose Regimens
Cancer Res 2004 64: 3994-4000. [Abstract] [Full Text] [PDF]  

Immunology:

Carla De Giovanni, Giordano Nicoletti, Lorena Landuzzi, Annalisa Astolfi, Stefania Croci, Alberto Comes, Silvano Ferrini, Raffaella Meazza, Manuela Iezzi, Emma Di Carlo, Piero Musiani, Federica Cavallo, Patrizia Nanni, and Pier-Luigi Lollini

Immunoprevention of HER-2/neu Transgenic Mammary Carcinoma through an Interleukin 12-Engineered Allogeneic Cell Vaccine
Cancer Res 2004 64: 4001-4009. [Abstract] [Full Text] [PDF] Supplementary Data  

Kenji Kawada, Masahiro Sonoshita, Hiromi Sakashita, Arimichi Takabayashi, Yoshio Yamaoka, Toshiaki Manabe, Kayo Inaba, Nagahiro Minato, Masanobu Oshima, and Makoto Mark Taketo

Pivotal Role of CXCR3 in Melanoma Cell Metastasis to Lymph Nodes
Cancer Res 2004 64: 4010-4017. [Abstract] [Full Text] [PDF]  

Pei Xiang Xing, Xiu Feng Hu, Geoffrey A. Pietersz, Howard L. Hosick, and Ian F. C. McKenzie

Cripto: A Novel Target for Antibody-Based Cancer Immunotherapy
Cancer Res 2004 64: 4018-4023. [Abstract] [Full Text] [PDF]  

Martijn H. M. G. M. den Brok, Roger P. M. Sutmuller, Robbert van der Voort, Erik J. Bennink, Carl G. Figdor, Theo J. M. Ruers, and Gosse J. Adema

In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity
Cancer Res 2004 64: 4024-4029. [Abstract] [Full Text] [PDF]  

Endocrinology:

Kerrie B. Bouker, Todd C. Skaar, David R. Fernandez, Kerry A. O’Brien, Rebecca B. Riggins, Donghua Cao, and Robert Clarke

Interferon Regulatory Factor-1 Mediates the Proapoptotic but Not Cell Cycle Arrest Effects of the Steroidal Antiestrogen ICI 182,780 (Faslodex, Fulvestrant)
Cancer Res 2004 64: 4030-4039. [Abstract] [Full Text] [PDF]  

Clinical Research:

Lars Dyrskjøt, Mogens Kruhøffer, Thomas Thykjaer, Niels Marcussen, Jens L. Jensen, Klaus Møller, and Torben F. Ørntoft

Gene Expression in the Urinary Bladder: A Common Carcinoma in Situ Gene Expression Signature Exists Disregarding Histopathological Classification
Cancer Res 2004 64: 4040-4048. [Abstract] [Full Text] [PDF]  

Epidemiology:

Karin A. Rosenblatt, Janet R. Daling, Chu Chen, Karen J. Sherman, and Stephen M. Schwartz

Marijuana Use and Risk of Oral Squamous Cell Carcinoma
Cancer Res 2004 64: 4049-4054. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Michael von Bergwelt-Baildon, Joachim L. Schultze, Britta Maecker, Isaura Menezes, Lee M. Nadler, Réjean Lapointe, Jacques Thibodeau, and Patrick Hwu

Correspondence re R. Lapointe et al., CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells. Cancer Res 2003;63:2836–43.
Cancer Res 2004 64: 4055-4057. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.