Reviews:

Experimental Design and Analysis of Antibody Microarrays: Applying Methods from cDNA Arrays

Jeanette E. Eckel-Passow, Antje Hoering, Terry M. Therneau, and Irene Ghobrial
Cancer Res 2005 65: 2985-2989. [Abstract] [Full Text] [PDF]  

Therapeutic Targeting of the Hedgehog-GLI Pathway in Prostate Cancer

Pilar Sanchez, Virginie Clement, and Ariel Ruiz i Altaba
Cancer Res 2005 65: 2990-2992. [Abstract] [Full Text] [PDF]  

Lysosomes as Targets for Cancer Therapy

Nicole Fehrenbacher and Marja Jäättelä
Cancer Res 2005 65: 2993-2995. [Abstract] [Full Text] [PDF]  

Editorial Note:

Genetics and Latinos: Proceedings of a National Summit

Amelie G. Ramirez and Jorge Gomez
Cancer Res 2005 65: 2996. [Full Text] [PDF]  

Perspectives in Cancer Research:

The Hydra Phenomenon of Cancer: Why Tumors Recur Locally after Microscopically Complete Resection

Michael Höckel and Nadja Dornhöfer
Cancer Res 2005 65: 2997-3002. [Abstract] [Full Text] [PDF]  

Priority Reports:

Epidermal Growth Factor Receptor Dynamics Influences Response to Epidermal Growth Factor Receptor Targeted Agents

Antonio Jimeno, Belen Rubio-Viqueira, Maria L. Amador, Darin Oppenheimer, Nadia Bouraoud, Peter Kulesza, Valeria Sebastiani, Anirban Maitra, and Manuel Hidalgo
Cancer Res 2005 65: 3003-3010. [Abstract] [Full Text] [PDF]  

Linking Transcriptional Elongation and Messenger RNA Export to Metastatic Breast Cancers

Shanchun Guo, Mohamed-Ali Hakimi, David Baillat, Xiaowei Chen, Michele J. Farber, Andres J.P. Klein-Szanto, Neil S. Cooch, Andrew K. Godwin, and Ramin Shiekhattar
Cancer Res 2005 65: 3011-3016. [Abstract] [Full Text] [PDF]  

Activation of the Fas-FasL Signaling Pathway by MDA-7/IL-24 Kills Human Ovarian Cancer Cells

Began Gopalan, Anya Litvak, Sikha Sharma, Abner M. Mhashilkar, Sunil Chada, and Rajagopal Ramesh
Cancer Res 2005 65: 3017-3024. [Abstract] [Full Text] [PDF] Supplementary Data  

Stem and Progenitor-Like Cells Contribute to the Aggressive Behavior of Human Epithelial Ovarian Cancer

Sharmila A. Bapat, Avinash M. Mali, Chaitanyananda B. Koppikar, and Nawneet K. Kurrey
Cancer Res 2005 65: 3025-3029. [Abstract] [Full Text] [PDF] Supplementary Data  

Metabolic Characterization of Human Prostate Cancer with Tissue Magnetic Resonance Spectroscopy

Leo L. Cheng, Melissa A. Burns, Jennifer L. Taylor, Wenlei He, Elkan F. Halpern, W. Scott McDougal, and Chin-Lee Wu
Cancer Res 2005 65: 3030-3034. [Abstract] [Full Text] [PDF]  

Spontaneous Human Adult Stem Cell Transformation

Daniel Rubio, Javier Garcia-Castro, María C. Martín, Ricardo de la Fuente, Juan C. Cigudosa, Alison C. Lloyd, and Antonio Bernad
Cancer Res 2005 65: 3035-3039. [Abstract] [Full Text] [PDF] Supplementary Data  

Ceratamines, Structurally Simple Microtubule-Stabilizing Antimitotic Agents with Unusual Cellular Effects

Geoffrey Karjala, Queenie Chan, Emiliano Manzo, Raymond J. Andersen, and Michel Roberge
Cancer Res 2005 65: 3040-3043. [Abstract] [Full Text] [PDF]  

Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion

Arnold H. Zea, Paulo C. Rodriguez, Michael B. Atkins, Claudia Hernandez, Sabina Signoretti, Jovanny Zabaleta, David McDermott, David Quiceno, Amanda Youmans, Anne O'Neill, James Mier, and Augusto C. Ochoa
Cancer Res 2005 65: 3044-3048. [Abstract] [Full Text] [PDF] Supplementary Data  

SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study

Alfonso Cristaudo, Rudy Foddis, Agnese Vivaldi, Rodolfo Buselli, Vittorio Gattini, Giovanni Guglielmi, Francesca Cosentino, Franco Ottenga, Eugenio Ciancia, Roberta Libener, Rosangela Filiberti, Monica Neri, PierGiacomo Betta, Mauro Tognon, Luciano Mutti, and Riccardo Puntoni
Cancer Res 2005 65: 3049-3052. [Abstract] [Full Text] [PDF]  

Loss of Heterozygosity in Childhood Acute Lymphoblastic Leukemia Detected by Genome-Wide Microarray Single Nucleotide Polymorphism Analysis

Julie A.E. Irving, Lisa Bloodworth, Nick P. Bown, Marian C. Case, Linda A. Hogarth, and Andrew G. Hall
Cancer Res 2005 65: 3053-3058. [Abstract] [Full Text] [PDF]  

Serum Soluble Epidermal Growth Factor Receptor Concentrations Decrease in Postmenopausal Metastatic Breast Cancer Patients Treated with Letrozole

Jacqueline M. Lafky, Andre T. Baron, Elsa M. Cora, David W. Hillman, Vera J. Suman, Edith A. Perez, James N. Ingle, and Nita J. Maihle
Cancer Res 2005 65: 3059-3062. [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Gene Expression Profiling Allows Distinction between Primary and Metastatic Squamous Cell Carcinomas in the Lung

Simon G. Talbot, Cherry Estilo, Ellie Maghami, Inderpal S. Sarkaria, Duy Khanh Pham, Pornchai O-charoenrat, Nicholas D. Socci, Ivan Ngai, Diane Carlson, Ronald Ghossein, Agnes Viale, Bernard J. Park, Valerie W. Rusch, and Bhuvanesh Singh
Cancer Res 2005 65: 3063-3071. [Abstract] [Full Text] [PDF] Supplementary Data  

Expression of the Brn-3b Transcription Factor Correlates with Expression of HSP-27 in Breast Cancer Biopsies and Is Required for Maximal Activation of the HSP-27 Promoter

Sonia A. Lee, Daniel Ndisang, Chandrakant Patel, Jonathan H. Dennis, David J. Faulkes, Corrado D'Arrigo, Laila Samady, Saleha Farooqui-Kabir, Richard J. Heads, David S. Latchman, and Vishwanie S. Budhram-Mahadeo
Cancer Res 2005 65: 3072-3080. [Abstract] [Full Text] [PDF]  

Evidence for the Presence of Disease-Perturbed Networks in Prostate Cancer Cells by Genomic and Proteomic Analyses: A Systems Approach to Disease

Biaoyang Lin, James T. White, Wei Lu, Tao Xie, Angelita G. Utleg, Xiaowei Yan, Eugene C. Yi, Paul Shannon, Irina Khrebtukova, Paul H. Lange, David R. Goodlett, Daixing Zhou, Thomas J. Vasicek, and Leroy Hood
Cancer Res 2005 65: 3081-3091. [Abstract] [Full Text] [PDF] Supplementary Data  

Overexpressed P-Cadherin/CDH3 Promotes Motility of Pancreatic Cancer Cells by Interacting with p120ctn and Activating Rho-Family GTPases

Keisuke Taniuchi, Hidewaki Nakagawa, Masayo Hosokawa, Toru Nakamura, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Toyomasa Katagiri, and Yusuke Nakamura
Cancer Res 2005 65: 3092-3099. [Abstract] [Full Text] [PDF]  

Influence of Mast Cells on Structural and Functional Manifestations of Radiation-Induced Heart Disease

Marjan Boerma, Junru Wang, Jan Wondergem, Jacob Joseph, Xiaohua Qiu, Richard H. Kennedy, and Martin Hauer-Jensen
Cancer Res 2005 65: 3100-3107. [Abstract] [Full Text] [PDF]  

The Serine/Threonine Protein Kinase, p90 Ribosomal S6 Kinase, Is an Important Regulator of Prostate Cancer Cell Proliferation

D.E. Clark, T.M. Errington, J.A. Smith, H.F. Frierson, Jr., M.J. Weber, and D.A. Lannigan
Cancer Res 2005 65: 3108-3116. [Abstract] [Full Text] [PDF]  

Cell and Tumor Biology:

RRP22 Is a Farnesylated, Nucleolar, Ras-Related Protein with Tumor Suppressor Potential

Candice Elam, Luke Hesson, Michele D. Vos, Kristin Eckfeld, Chad A. Ellis, Aaron Bell, Dietmar Krex, Michael J. Birrer, Farida Latif, and Geoffrey J. Clark
Cancer Res 2005 65: 3117-3125. [Abstract] [Full Text] [PDF]  

Tumorigenic Heterogeneity in Cancer Stem Cells Evolved from Long-term Cultures of Telomerase-Immortalized Human Mesenchymal Stem Cells

Jorge S. Burns, Basem M. Abdallah, Per Guldberg, Jørgen Rygaard, Henrik D. Schrøder, and Moustapha Kassem
Cancer Res 2005 65: 3126-3135. [Abstract] [Full Text] [PDF]  

Inhibition of a New Differentiation Pathway in Neuroblastoma by Copy Number Defects of N-myc, Cdc42, and nm23 Genes

Linda J. Valentijn, Arjen Koppen, Ronald van Asperen, Heather A. Root, Franciska Haneveld, and Rogier Versteeg
Cancer Res 2005 65: 3136-3145. [Abstract] [Full Text] [PDF]  

Progression of Barrett's Metaplasia to Adenocarcinoma Is Associated with the Suppression of the Transcriptional Programs of Epidermal Differentiation

Erik T. Kimchi, Mitchell C. Posner, James O. Park, Thomas E. Darga, Masha Kocherginsky, Theodore Karrison, John Hart, Kerrington D. Smith, James J. Mezhir, Ralph R. Weichselbaum, and Nikolai N. Khodarev
Cancer Res 2005 65: 3146-3154. [Abstract] [Full Text] [PDF] Supplementary Data  

Immortal DNA Strand Cosegregation Requires p53/IMPDH–Dependent Asymmetric Self-renewal Associated with Adult Stem Cells

Lakshmi Rambhatla, Sumati Ram-Mohan, Jennifer J. Cheng, and James L. Sherley
Cancer Res 2005 65: 3155-3161. [Abstract] [Full Text] [PDF]  

Down-regulation of Mitochondrial F₁F₀-ATP Synthase in Human Colon Cancer Cells with Induced 5-Fluorouracil Resistance

Young-Kyoung Shin, Byong Chul Yoo, Hee Jin Chang, Eunkyung Jeon, Sung-Hye Hong, Mi-Sun Jung, Soo-Jeong Lim, and Jae-Gahb Park
Cancer Res 2005 65: 3162-3170. [Abstract] [Full Text] [PDF]  

Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment

Ioanna Papandreou, Chaya Krishna, Fiona Kaper, Deli Cai, Amato J. Giaccia, and Nicholas C. Denko
Cancer Res 2005 65: 3171-3178. [Abstract] [Full Text] [PDF]  

Pak1 Phosphorylation of Snail, a Master Regulator of Epithelial-to-Mesenchyme Transition, Modulates Snail's Subcellular Localization and Functions

Zhibo Yang, Suresh Rayala, Diep Nguyen, Ratna K. Vadlamudi, Shiuan Chen, and Rakesh Kumar
Cancer Res 2005 65: 3179-3184. [Abstract] [Full Text] [PDF]  

Fetal Stromal–Dependent Paracrine and Intracrine Vascular Endothelial Growth Factor-A/Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Proliferation and Motility of Human Primary Myeloma Cells

Loïc Vincent, David K. Jin, Matthias A. Karajannis, Koji Shido, Andrea T. Hooper, William K. Rashbaum, Bronislaw Pytowski, Yan Wu, Daniel J. Hicklin, Zhenping Zhu, Peter Bohlen, Ruben Niesvizky, and Shahin Rafii
Cancer Res 2005 65: 3185-3192. [Abstract] [Full Text] [PDF]  

Extracellular Matrix Metalloproteinase Inducer Stimulates Tumor Angiogenesis by Elevating Vascular Endothelial Cell Growth Factor and Matrix Metalloproteinases

Yi Tang, Marian T. Nakada, Prabakaran Kesavan, Francis McCabe, Hillary Millar, Patricia Rafferty, Peter Bugelski, and Li Yan
Cancer Res 2005 65: 3193-3199. [Abstract] [Full Text] [PDF] Supplementary Data  

The Contribution of Bone Marrow–Derived Cells to the Tumor Vasculature in Neuroblastoma Is Matrix Metalloproteinase-9 Dependent

Sonata Jodele, Christophe F. Chantrain, Laurence Blavier, Carolyn Lutzko, Gay M. Crooks, Hiroyuki Shimada, Lisa M. Coussens, and Yves A. DeClerck
Cancer Res 2005 65: 3200-3208. [Abstract] [Full Text] [PDF]  

Nuclear Factor-B–Dependent Mechanisms in Breast Cancer Cells Regulate Tumor Burden and Osteolysis in Bone

Andrew H. Gordon, Regis J. O'Keefe, Edward M. Schwarz, Randy N. Rosier, and J. Edward Puzas
Cancer Res 2005 65: 3209-3217. [Abstract] [Full Text] [PDF]  

High Nuclear S100A6 (Calcyclin) Is Significantly Associated with Poor Survival in Pancreatic Cancer Patients

Dale Vimalachandran, William Greenhalf, Christopher Thompson, Jutta Lüttges, Wendy Prime, Fiona Campbell, Andrew Dodson, Richard Watson, Tatjana Crnogorac-Jurcevic, Nicholas Lemoine, John Neoptolemos, and Eithne Costello
Cancer Res 2005 65: 3218-3225. [Abstract] [Full Text] [PDF]  

Inhibition of Mammalian Target of Rapamycin Reverses Alveolar Epithelial Neoplasia Induced by Oncogenic K-ras

Marie Wislez, M. Loreto Spencer, Julie G. Izzo, Denise M. Juroske, Kamna Balhara, Dianna D. Cody, Roger E. Price, Walter N. Hittelman, Ignacio I. Wistuba, and Jonathan M. Kurie
Cancer Res 2005 65: 3226-3235. [Abstract] [Full Text] [PDF] Supplementary Data  

Mitochondrial Damage Mediates Genotoxicity of Arsenic in Mammalian Cells

Su-Xian Liu, Mercy M. Davidson, Xiuwei Tang, Winsome F. Walker, Mohammad Athar, Vladimir Ivanov, and Tom K. Hei
Cancer Res 2005 65: 3236-3242. [Abstract] [Full Text] [PDF]  

Suppression of Ovarian Cancer Cell Tumorigenicity and Evasion of Cisplatin Resistance Using a Truncated Epidermal Growth Factor Receptor in a Rat Model

John K. Chan, Huyen Pham, Xue Juan You, Noelle G. Cloven, Robert A. Burger, G. Scott Rose, Kristi Van Nostrand, Murray Korc, Philip J. DiSaia, and Hung Fan
Cancer Res 2005 65: 3243-3248. [Abstract] [Full Text] [PDF]  

Mouse p10, an Alternative Spliced Form of p15^INK4b, Inhibits Cell Cycle Progression and Malignant Transformation

Ignacio Pérez de Castro, Marta Benet, María Jiménez, Saba Alzabin, Marcos Malumbres, and Angel Pellicer
Cancer Res 2005 65: 3249-3256. [Abstract] [Full Text] [PDF]  

A Hypoxia-Independent Hypoxia-Inducible Factor-1 Activation Pathway Induced by Phosphatidylinositol-3 Kinase/Akt in HER2 Overexpressing Cells

Yan M. Li, Binhua P. Zhou, Jiong Deng, Yong Pan, Nissim Hay, and Mien-Chie Hung
Cancer Res 2005 65: 3257-3263. [Abstract] [Full Text] [PDF]  

BCR-ABL Induces the Expression of Skp2 through the PI3K Pathway to Promote p27^Kip1 Degradation and Proliferation of Chronic Myelogenous Leukemia Cells

Enrique J. Andreu, Elisa Lledó, Enric Poch, Carmen Ivorra, M. Pilar Albero, José Angel Martínez-Climent, Cristina Montiel-Duarte, José Rifón, Javier Pérez-Calvo, Cristina Arbona, Felipe Prósper, and Ignacio Pérez-Roger
Cancer Res 2005 65: 3264-3272. [Abstract] [Full Text] [PDF]  

Cortactin Overexpression Inhibits Ligand-Induced Down-regulation of the Epidermal Growth Factor Receptor

Paul Timpson, Danielle K. Lynch, Daniel Schramek, Francesca Walker, and Roger J. Daly
Cancer Res 2005 65: 3273-3280. [Abstract] [Full Text] [PDF]  

Role for the Nuclear Factor B Pathway in Transforming Growth Factor-ß1 Production in Idiopathic Myelofibrosis: Possible Relationship with FK506 Binding Protein 51 Overexpression

Emiko Komura, Carole Tonetti, Virginie Penard-Lacronique, Hédia Chagraoui, Catherine Lacout, Jean Pierre LeCouédic, Philippe Rameau, Najet Debili, William Vainchenker, and Stéphane Giraudier
Cancer Res 2005 65: 3281-3289. [Abstract] [Full Text] [PDF]  

Defective p38 Mitogen-Activated Protein Kinase Signaling Impairs Chemotaxic but not Proliferative Responses to Stromal-Derived Factor-1 in Acute Lymphoblastic Leukemia

Linda J. Bendall, Rana Baraz, Julius Juarez, Wei Shen, and Kenneth F. Bradstock
Cancer Res 2005 65: 3290-3298. [Abstract] [Full Text] [PDF]  

Differential Gene Up-Regulation by Hypoxia-Inducible Factor-1 and Hypoxia-Inducible Factor-2 in HEK293T Cells

Victoria Wang, David A. Davis, Muzammel Haque, L. Eric Huang, and Robert Yarchoan
Cancer Res 2005 65: 3299-3306. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas

Akira Nakamizo, Frank Marini, Toshiyuki Amano, Asadullah Khan, Matus Studeny, Joy Gumin, Julianne Chen, Stephen Hentschel, Giacomo Vecil, Jennifer Dembinski, Michael Andreeff, and Frederick F. Lang
Cancer Res 2005 65: 3307-3318. [Abstract] [Full Text] [PDF]  

Mitochondrial Targeting of Human O⁶-Methylguanine DNA Methyltransferase Protects against Cell Killing by Chemotherapeutic Alkylating Agents

Shanbao Cai, Yi Xu, Ryan J. Cooper, Michael J. Ferkowicz, Jennifer R. Hartwell, Karen E. Pollok, and Mark R. Kelley
Cancer Res 2005 65: 3319-3327. [Abstract] [Full Text] [PDF]  

Mechanisms of Enhanced Radiation Response following Epidermal Growth Factor Receptor Signaling Inhibition by Erlotinib (Tarceva)

Prakash Chinnaiyan, Shyhmin Huang, Geetha Vallabhaneni, Eric Armstrong, Sooryanarayana Varambally, Scott A. Tomlins, Arul M. Chinnaiyan, and Paul M. Harari
Cancer Res 2005 65: 3328-3335. [Abstract] [Full Text] [PDF]  

Synergistic Augmentation of Rapamycin-Induced Autophagy in Malignant Glioma Cells by Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibitors

Hayato Takeuchi, Yasuko Kondo, Keishi Fujiwara, Takao Kanzawa, Hiroshi Aoki, Gordon B. Mills, and Seiji Kondo
Cancer Res 2005 65: 3336-3346. [Abstract] [Full Text] [PDF]  

Construction of a Minimal HIV-1 Variant that Selectively Replicates in Leukemic Derived T-Cell Lines: Towards a New Virotherapy Approach

Rienk E. Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, and Ben Berkhout
Cancer Res 2005 65: 3347-3355. [Abstract] [Full Text] [PDF] Supplementary Data  

Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition

Mounia Beloueche-Babari, L. Elizabeth Jackson, Nada M.S. Al-Saffar, Paul Workman, Martin O. Leach, and Sabrina M. Ronen
Cancer Res 2005 65: 3356-3363. [Abstract] [Full Text] [PDF]  

Phenoxodiol, a Novel Isoflavone, Induces G₁ Arrest by Specific Loss in Cyclin-Dependent Kinase 2 Activity by p53-Independent Induction of p21^WAF1/CIP1

Martin F. Aguero, Maria M. Facchinetti, Zhanna Sheleg, and Adrian M. Senderowicz
Cancer Res 2005 65: 3364-3373. [Abstract] [Full Text] [PDF]  

C-C Chemokine Receptor 5 on Stromal Cells Promotes Pulmonary Metastasis

Hendrik W. van Deventer, William O'Connor, Jr., W. June Brickey, Robert M. Aris, Jenny P.Y. Ting, and Jonathan S. Serody
Cancer Res 2005 65: 3374-3379. [Abstract] [Full Text] [PDF]  

Target Cell–Restricted Apoptosis Induction of Acute Leukemic T Cells by a Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Protein with Specificity for Human CD7

Edwin Bremer, Douwe F. Samplonius, Matthias Peipp, Linda van Genne, Bart-Jan Kroesen, Georg H. Fey, Martin Gramatzki, Lou F.M.H. de Leij, and Wijnand Helfrich
Cancer Res 2005 65: 3380-3388. [Abstract] [Full Text] [PDF]  

Anticancer Activity of the Antibiotic Clioquinol

Wei-Qun Ding, Bolin Liu, Joshua L. Vaught, Hanako Yamauchi, and Stuart E. Lind
Cancer Res 2005 65: 3389-3395. [Abstract] [Full Text] [PDF]  

Dietary Genistein Reduces Metastasis in a Postsurgical Orthotopic Breast Cancer Model

Sharon A. Vantyghem, Sylvia M. Wilson, Carl O. Postenka, Waleed Al-Katib, Alan B. Tuck, and Ann F. Chambers
Cancer Res 2005 65: 3396-3403. [Abstract] [Full Text] [PDF]  

Inhibition of HER-2/neu Kinase Impairs Androgen Receptor Recruitment to the Androgen Responsive Enhancer

Yuanbo Liu, Samarpan Majumder, Wesley McCall, Carolyn I. Sartor, James L. Mohler, Christopher W. Gregory, H. Shelton Earp, and Young E. Whang
Cancer Res 2005 65: 3404-3409. [Abstract] [Full Text] [PDF]  

Immunology:

DNA Vaccine Expressing the Mimotope of GD2 Ganglioside Induces Protective GD2 Cross-reactive Antibody Responses

Elizabeth Bolesta, Aleksandra Kowalczyk, Andrzej Wierzbicki, Piotr Rotkiewicz, Barbara Bambach, Chun-Yen Tsao, Irena Horwacik, Andrzej Kolinski, Hanna Rokita, Martin Brecher, Xinhui Wang, Soldano Ferrone, and Danuta Kozbor
Cancer Res 2005 65: 3410-3418. [Abstract] [Full Text] [PDF]  

A DNA Vaccine Targeting Fos-Related Antigen 1 Enhanced by IL-18 Induces Long-lived T-Cell Memory against Tumor Recurrence

Yunping Luo, He Zhou, Masato Mizutani, Noriko Mizutani, Cheng Liu, Rong Xiang, and Ralph A. Reisfeld
Cancer Res 2005 65: 3419-3427. [Abstract] [Full Text] [PDF]  

Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles

Roberta Mortarini, Alessia Scarito, Daisuke Nonaka, Marina Zanon, Ilaria Bersani, Elisabetta Montaldi, Elisabetta Pennacchioli, Roberto Patuzzo, Mario Santinami, and Andrea Anichini
Cancer Res 2005 65: 3428-3436. [Abstract] [Full Text] [PDF] Supplementary Data  

Redirecting In vivo Elicited Tumor Infiltrating Macrophages and Dendritic Cells towards Tumor Rejection

Cristiana Guiducci, Alain P. Vicari, Sabina Sangaletti, Giorgio Trinchieri, and Mario P. Colombo
Cancer Res 2005 65: 3437-3446. [Abstract] [Full Text] [PDF] Supplementary Data  

IFN Unresponsiveness in LNCaP Cells Due to the Lack of JAK1 Gene Expression

Gavin P. Dunn, Kathleen C.F. Sheehan, Lloyd J. Old, and Robert D. Schreiber
Cancer Res 2005 65: 3447-3453. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Combined Genetic Assessment of Transforming Growth Factor-ß Signaling Pathway Variants May Predict Breast Cancer Risk

Virginia G. Kaklamani, Lisa Baddi, Junjian Liu, Diana Rosman, Sharbani Phukan, Ciarán Bradley, Chris Hegarty, Bree McDaniel, Alfred Rademaker, Carole Oddoux, Harry Ostrer, Loren S. Michel, Helen Huang, Yu Chen, Habibul Ahsan, Kenneth Offit, and Boris Pasche
Cancer Res 2005 65: 3454-3461. [Abstract] [Full Text] [PDF]  

The Retinoid X Receptor-Selective Retinoid, LGD1069, Down-regulates Cyclooxygenase-2 Expression in Human Breast Cells through Transcription Factor Crosstalk: Implications for Molecular-Based Chemoprevention

Gu Kong, Hee-Tae Kim, Kendall Wu, David DeNardo, Susan G. Hilsenbeck, Xiao-Chun Xu, William W. Lamph, Reid Bissonnette, Andrew J. Dannenberg, and Powel H. Brown
Cancer Res 2005 65: 3462-3469. [Abstract] [Full Text] [PDF]  

Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells

Xiaoke Huang, Shan Chen, Li Xu, Yueqin Liu, Dilip K. Deb, Leonidas C. Platanias, and Raymond C. Bergan
Cancer Res 2005 65: 3470-3478. [Abstract] [Full Text] [PDF]  

Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice

Xiaolin Zi and Anne R. Simoneau
Cancer Res 2005 65: 3479-3486. [Abstract] [Full Text] [PDF] Supplementary Data  

Selenium Disrupts Estrogen Signaling by Altering Estrogen Receptor Expression and Ligand Binding in Human Breast Cancer Cells

Soo Ok Lee, Nagalakshmi Nadiminty, Xiu Xian Wu, Wei Lou, Yan Dong, Clement Ip, Sergio A. Onate, and Allen C. Gao
Cancer Res 2005 65: 3487-3492. [Abstract] [Full Text] [PDF]  

Tamoxifen Inhibition of Estrogen Receptor-–Negative Mouse Mammary Tumorigenesis

Daniel Medina, Frances S. Kittrell, Jamal Hill, Anne Shepard, Gudmundur Thordarson, and Powel Brown
Cancer Res 2005 65: 3493-3496. [Abstract] [Full Text] [PDF]  

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