Special Workshop Report:

Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells

Michael F. Clarke, John E. Dick, Peter B. Dirks, Connie J. Eaves, Catriona H.M. Jamieson, D. Leanne Jones, Jane Visvader, Irving L. Weissman, and Geoffrey M. Wahl
Cancer Res 2006 66: 9339-9344. Published Online First September 21, 2006. doi: 10.1158/0008-5472.CAN-06-3126 [Full Text] [PDF]  

Reviews:

Genetic Interaction between Rb and N-ras: Differentiation Control and Metastasis

Chiaki Takahashi and Mark E. Ewen
Cancer Res 2006 66: 9345-9348. doi: 10.1158/0008-5472.CAN-06-1250 [Abstract] [Full Text] [PDF]  

Autophagy in Cancer: Good, Bad, or Both?

Melanie M. Hippert, Patrick S. O'Toole, and Andrew Thorburn
Cancer Res 2006 66: 9349-9351. doi: 10.1158/0008-5472.CAN-06-1597 [Abstract] [Full Text] [PDF]  

Enhancer of Zeste 2 as a Marker of Preneoplastic Progression in the Breast

Lei Ding and Celina G. Kleer
Cancer Res 2006 66: 9352-9355. doi: 10.1158/0008-5472.CAN-06-2384 [Abstract] [Full Text] [PDF]  

Priority Reports:

Inhibition of p53 Response in Tumor Stroma Improves Efficacy of Anticancer Treatment by Increasing Antiangiogenic Effects of Chemotherapy and Radiotherapy in Mice

Lyudmila G. Burdelya, Elena A. Komarova, Jason E. Hill, Timothy Browder, Natalia D. Tararova, Lori Mavrakis, Paul E. DiCorleto, Judah Folkman, and Andrei V. Gudkov
Cancer Res 2006 66: 9356-9361. doi: 10.1158/0008-5472.CAN-06-1223 [Abstract] [Full Text] [PDF]  

Tumor-Specific p73 Up-regulation Mediates p63 Dependence in Squamous Cell Carcinoma

Maurice Phillip DeYoung, Cory M. Johannessen, Chee-Onn Leong, William Faquin, James W. Rocco, and Leif W. Ellisen
Cancer Res 2006 66: 9362-9368. doi: 10.1158/0008-5472.CAN-06-1619 [Abstract] [Full Text] [PDF]  

Genomic Copy Number Changes Affecting the Thymidylate Synthase (TYMS) Gene in Cancer: A Model for Patient Classification to Aid Fluoropyrimidine Therapy

Jonathan R. Brody, Tomas Hucl, Eike Gallmeier, Jordan M. Winter, Scott E. Kern, and Kathleen M. Murphy
Cancer Res 2006 66: 9369-9373. doi: 10.1158/0008-5472.CAN-06-2165 [Abstract] [Full Text] [PDF]  

Dietary Administration of the Proapoptotic Vitamin E Analogue -Tocopheryloxyacetic Acid Inhibits Metastatic Murine Breast Cancer

Tobias Hahn, Lajos Szabo, Mikhal Gold, Lalitha Ramanathapuram, Laurence H. Hurley, and Emmanuel T. Akporiaye
Cancer Res 2006 66: 9374-9378. doi: 10.1158/0008-5472.CAN-06-2403 [Abstract] [Full Text] [PDF]  

Targeted Disruption of Protein Kinase C Reduces Cell Invasion and Motility through Inactivation of RhoA and RhoC GTPases in Head and Neck Squamous Cell Carcinoma

Quintin Pan, Li Wei Bao, Theodoros N. Teknos, and Sofia D. Merajver
Cancer Res 2006 66: 9379-9384. doi: 10.1158/0008-5472.CAN-06-2646 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

TSLC1 Is a Tumor Suppressor Gene Associated with Metastasis in Nasopharyngeal Carcinoma

Hong Lok Lung, Arthur Kwok Leung Cheung, Dan Xie, Yue Cheng, Fung Mei Kwong, Yoshinori Murakami, Xin-Yuan Guan, Jonathan Shuntong Sham, Daniel Chua, Alexey I. Protopopov, Eugene R. Zabarovsky, Sai Wah Tsao, Eric J. Stanbridge, and Maria Li Lung
Cancer Res 2006 66: 9385-9392. doi: 10.1158/0008-5472.CAN-06-0590 [Abstract] [Full Text] [PDF]  

Critical Roles for Non-pRb Targets of Human Papillomavirus Type 16 E7 in Cervical Carcinogenesis

Scott Balsitis, Fred Dick, Nicholas Dyson, and Paul F. Lambert
Cancer Res 2006 66: 9393-9400. doi: 10.1158/0008-5472.CAN-06-0984 [Abstract] [Full Text] [PDF]  

Deleted in Colorectal Cancer Is a Putative Conditional Tumor-Suppressor Gene Inactivated by Promoter Hypermethylation in Head and Neck Squamous Cell Carcinoma

André Lopes Carvalho, Alice Chuang, Wei-Wen Jiang, Juna Lee, Shahnaz Begum, Luana Poeta, Ming Zhao, Carmen Jerónimo, Rui Henrique, Chetan S. Nayak, Hannah L. Park, Mariana R.O. Brait, Chunyan Liu, Shaoyu Zhou, Wayne Koch, Vito Michele Fazio, Edward Ratovitski, Barry Trink, William Westra, David Sidransky, Chul-so Moon, and Joseph A. Califano
Cancer Res 2006 66: 9401-9407. doi: 10.1158/0008-5472.CAN-06-1073 [Abstract] [Full Text] [PDF]  

The Neuromedin U-Growth Hormone Secretagogue Receptor 1b/Neurotensin Receptor 1 Oncogenic Signaling Pathway as a Therapeutic Target for Lung Cancer

Koji Takahashi, Chiyuki Furukawa, Atsushi Takano, Nobuhisa Ishikawa, Tatsuya Kato, Satoshi Hayama, Chie Suzuki, Wataru Yasui, Kouki Inai, Saburo Sone, Tomoo Ito, Hitoshi Nishimura, Eiju Tsuchiya, Yusuke Nakamura, and Yataro Daigo
Cancer Res 2006 66: 9408-9419. doi: 10.1158/0008-5472.CAN-06-1349 [Abstract] [Full Text] [PDF] Supplementary Data  

ERCC4 Associated with Breast Cancer Risk: A Two-Stage Case-Control Study Using High-throughput Genotyping

Roger Laughlin Milne, Gloria Ribas, Anna González-Neira, Rainer Fagerholm, Antonio Salas, Emilio González, Joaquín Dopazo, Heli Nevanlinna, Mercedes Robledo, and Javier Benítez
Cancer Res 2006 66: 9420-9427. doi: 10.1158/0008-5472.CAN-06-1418 [Abstract] [Full Text] [PDF]  

High-resolution Global Genomic Survey of 178 Gliomas Reveals Novel Regions of Copy Number Alteration and Allelic Imbalances

Yuri Kotliarov, Mary Ellen Steed, Neil Christopher, Jennifer Walling, Qin Su, Angela Center, John Heiss, Mark Rosenblum, Tom Mikkelsen, Jean C. Zenklusen, and Howard A. Fine
Cancer Res 2006 66: 9428-9436. doi: 10.1158/0008-5472.CAN-06-1691 [Abstract] [Full Text] [PDF] Supplementary Data  

Squamous Cell Carcinoma Related Oncogene/DCUN1D1 Is Highly Conserved and Activated by Amplification in Squamous Cell Carcinomas

Inderpal Sarkaria, Pornchai O-charoenrat, Simon G. Talbot, Pabbathi G. Reddy, Ivan Ngai, Ellie Maghami, Kepal N. Patel, Benjamin Lee, Yoshihiro Yonekawa, Maria Dudas, Andrew Kaufman, Russell Ryan, Ronald Ghossein, Pulivarthi H. Rao, Archontoula Stoffel, Y. Ramanathan, and Bhuvanesh Singh
Cancer Res 2006 66: 9437-9444. doi: 10.1158/0008-5472.CAN-06-2074 [Abstract] [Full Text] [PDF] Supplementary Data  

An EBF3-Mediated Transcriptional Program That Induces Cell Cycle Arrest and Apoptosis

Lisa Y. Zhao, Yuxin Niu, Aleixo Santiago, Jilin Liu, Sara H. Albert, Keith D. Robertson, and Daiqing Liao
Cancer Res 2006 66: 9445-9452. doi: 10.1158/0008-5472.CAN-06-1713 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Cancer Cell Migration and Invasion by Ectopic Synthesis of Coagulation Factor VII

Shiro Koizume, Ming-Shou Jin, Etsuko Miyagi, Fumiki Hirahara, Yoshiyasu Nakamura, Jin-Hua Piao, Akio Asai, Akira Yoshida, Eiju Tsuchiya, Wolfram Ruf, and Yohei Miyagi
Cancer Res 2006 66: 9453-9460. doi: 10.1158/0008-5472.CAN-06-1803 [Abstract] [Full Text] [PDF]  

Estrogen-Induced Activation of Mammalian Target of Rapamycin Is Mediated via Tuberin and the Small GTPase Ras Homologue Enriched in Brain

Jane Yu and Elizabeth Petri Henske
Cancer Res 2006 66: 9461-9466. doi: 10.1158/0008-5472.CAN-06-1895 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Regulation of hdm2 by Stress-Induced hdm2^alt1 in Tumor and Nontumorigenic Cell Lines Correlating with p53 Stability

Chrisanne S. Dias, Yan Liu, Amy Yau, Lindsay Westrick, and Susan C. Evans
Cancer Res 2006 66: 9467-9473. doi: 10.1158/0008-5472.CAN-05-3013 [Abstract] [Full Text] [PDF]  

The Synovial Sarcoma–Associated SS18-SSX2 Fusion Protein Induces Epigenetic Gene (De)Regulation

Diederik R.H. de Bruijn, Susanne V. Allander, Anke H.A. van Dijk, Marieke P. Willemse, Jose Thijssen, Jan J.M. van Groningen, Paul S. Meltzer, and Ad Geurts van Kessel
Cancer Res 2006 66: 9474-9482. doi: 10.1158/0008-5472.CAN-05-3726 [Abstract] [Full Text] [PDF] Supplementary Data  

In Melanoma, RAS Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling

Nicolas Dumaz, Robert Hayward, Jan Martin, Lesley Ogilvie, Douglas Hedley, John A. Curtin, Boris C. Bastian, Caroline Springer, and Richard Marais
Cancer Res 2006 66: 9483-9491. doi: 10.1158/0008-5472.CAN-05-4227 [Abstract] [Full Text] [PDF] Supplementary Data  

Transgenic Mice Expressing the p75 CCAAT-Displacement Protein/Cut Homeobox Isoform Develop a Myeloproliferative Disease–Like Myeloid Leukemia

Chantal Cadieux, Sylvie Fournier, Alan C. Peterson, Christian Bédard, Barry J. Bedell, and Alain Nepveu
Cancer Res 2006 66: 9492-9501. doi: 10.1158/0008-5472.CAN-05-4230 [Abstract] [Full Text] [PDF] Supplementary Data  

Genotoxic Stress Induces Coordinately Regulated Alternative Splicing of the p53 Modulators MDM2 and MDM4

Dawn S. Chandler, Ravi K. Singh, Lisa C. Caldwell, Jaquelyn L. Bitler, and Guillermina Lozano
Cancer Res 2006 66: 9502-9508. doi: 10.1158/0008-5472.CAN-05-4271 [Abstract] [Full Text] [PDF] Supplementary Data  

Ras-induced Modulation of CXCL10 and Its Receptor Splice Variant CXCR3-B in MDA-MB-435 and MCF-7 Cells: Relevance for the Development of Human Breast Cancer

Dipak Datta, Jesse A. Flaxenburg, Sreenivas Laxmanan, Christopher Geehan, Martin Grimm, Ana Maria Waaga-Gasser, David M. Briscoe, and Soumitro Pal
Cancer Res 2006 66: 9509-9518. doi: 10.1158/0008-5472.CAN-05-4345 [Abstract] [Full Text] [PDF] Supplementary Data  

Oxidative Stress Induces ADAM9 Protein Expression in Human Prostate Cancer Cells

Shian-Ying Sung, Hiroyuki Kubo, Katsumi Shigemura, Rebecca S. Arnold, Sanjay Logani, Ruoxiang Wang, Hiroyuki Konaka, Masayuki Nakagawa, Spiro Mousses, Mahul Amin, Cynthia Anderson, Peter Johnstone, John A. Petros, Fray F. Marshall, Haiyen E. Zhau, and Leland W.K. Chung
Cancer Res 2006 66: 9519-9526. doi: 10.1158/0008-5472.CAN-05-4375 [Abstract] [Full Text] [PDF]  

HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition

Xinyan Wu, Hexin Chen, Belinda Parker, Ethel Rubin, Tao Zhu, Ji Shin Lee, Pedram Argani, and Saraswati Sukumar
Cancer Res 2006 66: 9527-9534. doi: 10.1158/0008-5472.CAN-05-4470 [Abstract] [Full Text] [PDF]  

Increased Fibroblast Growth Factor-Inducible 14 Expression Levels Promote Glioma Cell Invasion via Rac1 and Nuclear Factor-B and Correlate with Poor Patient Outcome

Nhan L. Tran, Wendy S. McDonough, Benjamin A. Savitch, Shannon P. Fortin, Jeffrey A. Winkles, Marc Symons, Mitsutoshi Nakada, Heather E. Cunliffe, Galen Hostetter, Dominique B. Hoelzinger, Jessica L. Rennert, Jennifer S. Michaelson, Linda C. Burkly, Christopher A. Lipinski, Joseph C. Loftus, Luigi Mariani, and Michael E. Berens
Cancer Res 2006 66: 9535-9542. doi: 10.1158/0008-5472.CAN-06-0418 [Abstract] [Full Text] [PDF] Supplementary Data  

Genetic Profiling of Epithelial Cells Expressing E-Cadherin Repressors Reveals a Distinct Role for Snail, Slug, and E47 Factors in Epithelial-Mesenchymal Transition

Gema Moreno-Bueno, Eva Cubillo, David Sarrió, Héctor Peinado, Socorro María Rodríguez-Pinilla, Sonia Villa, Victoria Bolós, Mireia Jordá, Angels Fabra, Francisco Portillo, José Palacios, and Amparo Cano
Cancer Res 2006 66: 9543-9556. doi: 10.1158/0008-5472.CAN-06-0479 [Abstract] [Full Text] [PDF] Supplementary Data  

Absence of CD9 Enhances Adhesion-Dependent Morphologic Differentiation, Survival, and Matrix Metalloproteinase-2 Production in Small Cell Lung Cancer Cells

Yoshiyuki Saito, Isao Tachibana, Yoshito Takeda, Hiroyuki Yamane, Ping He, Mayumi Suzuki, Seigo Minami, Takashi Kijima, Mitsuhiro Yoshida, Toru Kumagai, Tadashi Osaki, and Ichiro Kawase
Cancer Res 2006 66: 9557-9565. doi: 10.1158/0008-5472.CAN-06-1131 [Abstract] [Full Text] [PDF]  

Tumor-Induced Activation of Lymphatic Endothelial Cells via Vascular Endothelial Growth Factor Receptor-2 Is Critical for Prostate Cancer Lymphatic Metastasis

Yiping Zeng, Kenneth Opeskin, Jeremy Goad, and Elizabeth D. Williams
Cancer Res 2006 66: 9566-9575. doi: 10.1158/0008-5472.CAN-06-1488 [Abstract] [Full Text] [PDF] Supplementary Data  

The CXCR5 Chemokine Receptor Is Expressed by Carcinoma Cells and Promotes Growth of Colon Carcinoma in the Liver

Joost Meijer, Ingrid S. Zeelenberg, Bence Sipos, and Ed Roos
Cancer Res 2006 66: 9576-9582. doi: 10.1158/0008-5472.CAN-06-1507 [Abstract] [Full Text] [PDF]  

In vivo and In vitro Evidence for Transforming Growth Factor-ß1-Mediated Epithelial to Mesenchymal Transition in Esophageal Adenocarcinoma

Jonathan R.E. Rees, Benjamin A. Onwuegbusi, Vicki E. Save, Derek Alderson, and Rebecca C. Fitzgerald
Cancer Res 2006 66: 9583-9590. doi: 10.1158/0008-5472.CAN-06-1842 [Abstract] [Full Text] [PDF] Supplementary Data  

HER2/Neu (ErbB2) Signaling to Rac1-Pak1 Is Temporally and Spatially Modulated by Transforming Growth Factor ß

Shizhen Emily Wang, Incheol Shin, Frederick Y. Wu, David B. Friedman, and Carlos L. Arteaga
Cancer Res 2006 66: 9591-9600. doi: 10.1158/0008-5472.CAN-06-2071 [Abstract] [Full Text] [PDF]  

Non–Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation

Amit K. Das, Mitsuo Sato, Michael D. Story, Michael Peyton, Robert Graves, Stella Redpath, Luc Girard, Adi F. Gazdar, Jerry W. Shay, John D. Minna, and Chaitanya S. Nirodi
Cancer Res 2006 66: 9601-9608. doi: 10.1158/0008-5472.CAN-06-2627 [Abstract] [Full Text] [PDF] Supplementary Data  

Distinct Effects of Annexin A7 and p53 on Arachidonate Lipoxygenation in Prostate Cancer Cells Involve 5-Lipoxygenase Transcription

Yelizaveta Torosyan, Albert Dobi, Shanmugam Naga, Katerina Mezhevaya, Mirta Glasman, Christine Norris, Guisen Jiang, Gregory Mueller, Harvey Pollard, and Meera Srivastava
Cancer Res 2006 66: 9609-9616. doi: 10.1158/0008-5472.CAN-06-1574 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Targeting the Lymphotoxin-ß Receptor with Agonist Antibodies as a Potential Cancer Therapy

Matvey Lukashev, Doreen LePage, Cheryl Wilson, Véronique Bailly, Ellen Garber, Alex Lukashin, Apinya Ngam-ek, Weike Zeng, Norman Allaire, Steve Perrin, Xianghong Xu, Kendall Szeliga, Kathleen Wortham, Rebecca Kelly, Cindy Bottiglio, Jane Ding, Linda Griffith, Glenna Heaney, Erika Silverio, William Yang, Matt Jarpe, Stephen Fawell, Mitchell Reff, Amie Carmillo, Konrad Miatkowski, Joseph Amatucci, Thomas Crowell, Holly Prentice, Werner Meier, Shelia M. Violette, Fabienne Mackay, Dajun Yang, Robert Hoffman, and Jeffrey L. Browning
Cancer Res 2006 66: 9617-9624. doi: 10.1158/0008-5472.CAN-06-0217 [Abstract] [Full Text] [PDF] Supplementary Data  

PRL-3 Initiates Tumor Angiogenesis by Recruiting Endothelial Cells In vitro and In vivo

Ke Guo, Jie Li, Haihe Wang, Motomi Osato, Jing Ping Tang, Samantha Yiling Quah, Bin Qi Gan, and Qi Zeng
Cancer Res 2006 66: 9625-9635. doi: 10.1158/0008-5472.CAN-06-0726 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhanced Killing of Melanoma Cells by Simultaneously Targeting Mcl-1 and NOXA

Jian-Zhong Qin, Hong Xin, Leonid A. Sitailo, Mitchell F. Denning, and Brian J. Nickoloff
Cancer Res 2006 66: 9636-9645. doi: 10.1158/0008-5472.CAN-06-0747 [Abstract] [Full Text] [PDF]  

Small-Molecule MDM2 Antagonists as a New Therapy Concept for Neuroblastoma

Tom Van Maerken, Frank Speleman, Joëlle Vermeulen, Irina Lambertz, Sarah De Clercq, Els De Smet, Nurten Yigit, Vicky Coppens, Jan Philippé, Anne De Paepe, Jean-Christophe Marine, and Jo Vandesompele
Cancer Res 2006 66: 9646-9655. doi: 10.1158/0008-5472.CAN-06-0792 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Aminoflavone (NSC 686288) by a Sulfotransferase Is Required for the Antiproliferative Effect of the Drug and for Induction of Histone -H2AX

Ling-hua Meng, Uma Shankavaram, Chi Chen, Keli Agama, Hai-qing Fu, Frank J. Gonzalez, John Weinstein, and Yves Pommier
Cancer Res 2006 66: 9656-9664. doi: 10.1158/0008-5472.CAN-06-0796 [Abstract] [Full Text] [PDF]  

Host and Direct Antitumor Effects and Profound Reduction in Tumor Metastasis with Selective EP4 Receptor Antagonism

Li Yang, Yuhui Huang, Rut Porta, Kiyoshi Yanagisawa, Adriana Gonzalez, Eric Segi, David H. Johnson, Shuh Narumiya, and David P. Carbone
Cancer Res 2006 66: 9665-9672. doi: 10.1158/0008-5472.CAN-06-1271 [Abstract] [Full Text] [PDF]  

In vitro and In vivo Characterization of ⁶⁴Cu-Labeled Abegrin^TM, a Humanized Monoclonal Antibody against Integrin _vß₃

Weibo Cai, Yun Wu, Kai Chen, Qizhen Cao, David A. Tice, and Xiaoyuan Chen
Cancer Res 2006 66: 9673-9681. doi: 10.1158/0008-5472.CAN-06-1480 [Abstract] [Full Text] [PDF]  

The 3p21.3 Tumor Suppressor NPRL2 Plays an Important Role in Cisplatin-Induced Resistance in Human Non–Small-Cell Lung Cancer Cells

Kentaro Ueda, Hiroyuki Kawashima, Shoichiro Ohtani, Wu-Guo Deng, Murali Ravoori, Jim Bankson, Boning Gao, Luc Girard, John D. Minna, Jack A. Roth, Vikas Kundra, and Lin Ji
Cancer Res 2006 66: 9682-9690. doi: 10.1158/0008-5472.CAN-06-1483 [Abstract] [Full Text] [PDF]  

The COOH-Terminal Globular Domain of Fibrinogen Chain Suppresses Angiogenesis and Tumor Growth

Nobuaki Akakura, Case Hoogland, Yoko K. Takada, Jun Saegusa, Xiaojing Ye, Fu-Tong Liu, Anthony Tze-Wai Cheung, and Yoshikazu Takada
Cancer Res 2006 66: 9691-9697. doi: 10.1158/0008-5472.CAN-06-1686 [Abstract] [Full Text] [PDF]  

Mechanism of Reoxygenation after Antiangiogenic Therapy Using SU5416 and Its Importance for Guiding Combined Antitumor Therapy

Réginald Ansiaux, Christine Baudelet, Bénédicte F. Jordan, Nathalie Crokart, Philippe Martinive, Julie DeWever, Vincent Grégoire, Olivier Feron, and Bernard Gallez
Cancer Res 2006 66: 9698-9704. doi: 10.1158/0008-5472.CAN-06-1854 [Abstract] [Full Text] [PDF]  

Aldose Reductase Regulates Growth Factor-Induced Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Colon Cancer Cells

Ravinder Tammali, Kota V. Ramana, Sharad S. Singhal, Sanjay Awasthi, and Satish K. Srivastava
Cancer Res 2006 66: 9705-9713. doi: 10.1158/0008-5472.CAN-06-2105 [Abstract] [Full Text] [PDF] Supplementary Data  

Pyridone 6, A Pan-Janus–Activated Kinase Inhibitor, Induces Growth Inhibition of Multiple Myeloma Cells

Laura Pedranzini, Tobias Dechow, Marjan Berishaj, Raymond Comenzo, Ping Zhou, Janeen Azare, William Bornmann, and Jacqueline Bromberg
Cancer Res 2006 66: 9714-9721. doi: 10.1158/0008-5472.CAN-05-4280 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of an Agent Selectively Targeting DPC4 (Deleted in Pancreatic Cancer Locus 4)–Deficient Pancreatic Cancer Cells

Hong Wang, Haiyong Han, and Daniel D. Von Hoff
Cancer Res 2006 66: 9722-9730. doi: 10.1158/0008-5472.CAN-05-4602 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of a Chemical Inhibitor of the Oncogenic Transcription Factor Forkhead Box M1

Senthil K. Radhakrishnan, Uppoor G. Bhat, Douglas E. Hughes, I-Ching Wang, Robert H. Costa, and Andrei L. Gartel
Cancer Res 2006 66: 9731-9735. doi: 10.1158/0008-5472.CAN-06-1576 [Abstract] [Full Text] [PDF] Supplementary Data  

Antitumor Activity of an Oncolytic Adenovirus-Delivered Oncogene Small Interfering RNA

Yu-An Zhang, John Nemunaitis, Shirley K. Samuel, Patrick Chen, Yuqiao Shen, and Alex W. Tong
Cancer Res 2006 66: 9736-9743. doi: 10.1158/0008-5472.CAN-06-1617 [Abstract] [Full Text] [PDF] Supplementary Data  

The Differential Staurosporine-Mediated G₁ Arrest in Normal versus Tumor Cells Is Dependent on the Retinoblastoma Protein

Mollianne McGahren-Murray, Nicholas H.A. Terry, and Khandan Keyomarsi
Cancer Res 2006 66: 9744-9753. doi: 10.1158/0008-5472.CAN-06-1809 [Abstract] [Full Text] [PDF]  

Immunology:

The Tumor Antigen Repertoire Identified in Tumor-Bearing Neu Transgenic Mice Predicts Human Tumor Antigens

Hailing Lu, Keith L. Knutson, Ekram Gad, and Mary L. Disis
Cancer Res 2006 66: 9754-9761. doi: 10.1158/0008-5472.CAN-06-1083 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Involvement of Mitochondrial and Akt Signaling Pathways in Augmented Apoptosis Induced by a Combination of Low Doses of Celecoxib and N-(4-Hydroxyphenyl) Retinamide in Premalignant Human Bronchial Epithelial Cells

Claudia P. Schroeder, Humam Kadara, Dafna Lotan, Jong K. Woo, Ho-Young Lee, Waun Ki Hong, and Reuben Lotan
Cancer Res 2006 66: 9762-9770. doi: 10.1158/0008-5472.CAN-05-4124 [Abstract] [Full Text] [PDF]  

Common Genetic Variants in Proinflammatory and Other Immunoregulatory Genes and Risk for Non-Hodgkin Lymphoma

Sophia S. Wang, James R. Cerhan, Patricia Hartge, Scott Davis, Wendy Cozen, Richard K. Severson, Nilanjan Chatterjee, Meredith Yeager, Stephen J. Chanock, and Nathaniel Rothman
Cancer Res 2006 66: 9771-9780. doi: 10.1158/0008-5472.CAN-06-0324 [Abstract] [Full Text] [PDF] Supplementary Data  

Comprehensive Assessment of Genetic Variation of Catechol-O-Methyltransferase and Breast Cancer Risk

Mia M. Gaudet, Stephen Chanock, Jolanta Lissowska, Sonja I. Berndt, Beata Peplonska, Louise A. Brinton, Robert Welch, Meredith Yeager, Alicja Bardin-Mikolajczak, and Montserrat Garcia-Closas
Cancer Res 2006 66: 9781-9785. doi: 10.1158/0008-5472.CAN-06-1294 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

CD99-Positive "Ewing's Sarcoma" from Mouse Bone Marrow–Derived Mesenchymal Progenitor Cells?

Heinrich Kovar and Alain Bernard
Cancer Res 2006 66: 9786 [Full Text] [PDF]  

Ewing's Sarcoma–Like Tumors Originate from EWS-FLI-1-Expressing Mesenchymal Progenitor Cells

Nicolo Riggi, Mario-Luca Suvà, and Ivan Stamenkovic
Cancer Res 2006 66: 9786 [Full Text] [PDF]  

Models for Spontaneous Metastasis

Isaiah J. Fidler
Cancer Res 2006 66: 9787 [Full Text] [PDF]  

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