Reviews:

Quantitating Therapeutic Disruption of Tumor Blood Flow with Intravital Video Microscopy

Arthur M. Iga, Sandip Sarkar, Kevin M. Sales, Marc C. Winslet, and Alexander M. Seifalian
Cancer Res 2006 66: 11517-11519. doi: 10.1158/0008-5472.CAN-06-1743 [Abstract] [Full Text] [PDF]  

Pathophysiologic Effects of Vascular-Targeting Agents and the Implications for Combination with Conventional Therapies

Michael R. Horsman and Dietmar W. Siemann
Cancer Res 2006 66: 11520-11539. doi: 10.1158/0008-5472.CAN-06-2848 [Abstract] [Full Text] [PDF]  

Special Workshop Report:

Cancer Chemoprevention and Cancer Preventive Vaccines—A Call to Action: Leaders of Diverse Stakeholder Groups Present Strategies for Overcoming Multiple Barriers to Meet an Urgent Need

Ronald B. Herberman, Homer L. Pearce, Scott M. Lippman, Bruce S. Pyenson, and David S. Alberts
Cancer Res 2006 66: 11540-11549. Published Online First December 7, 2006. doi: 10.1158/0008-5472.CAN-06-4122 [Abstract] [Full Text] [PDF]  

Meeting Report:

Eighteenth Annual Pezcoller Symposium: Tumor Microenvironment and Heterotypic Interactions

Robert Weinberg and Enrico Mihich
Cancer Res 2006 66: 11550-11553. Published Online First December 7, 2006. doi: 10.1158/0008-5472.CAN-06-3149 [Abstract] [Full Text] [PDF]  

Priority Reports:

Ataxia Telangiectasia Mutated Down-regulates Phospho-Extracellular Signal-Regulated Kinase 1/2 via Activation of MKP-1 in Response to Radiation

Mukesh K. Nyati, Felix Y. Feng, Divya Maheshwari, Sooryanarayana Varambally, Steven P. Zielske, Aarif Ahsan, Patrick Y. Chun, Vinay A. Arora, Mary A. Davis, Mira Jung, Mats Ljungman, Christine E. Canman, Arul M. Chinnaiyan, and Theodore S. Lawrence
Cancer Res 2006 66: 11554-11559. doi: 10.1158/0008-5472.CAN-06-1935 [Abstract] [Full Text] [PDF] Supplementary Data  

SLC5A8 Triggers Tumor Cell Apoptosis through Pyruvate-Dependent Inhibition of Histone Deacetylases

Muthusamy Thangaraju, Elangovan Gopal, Pamela M. Martin, Sudha Ananth, Sylvia B. Smith, Puttur D. Prasad, Esta Sterneck, and Vadivel Ganapathy
Cancer Res 2006 66: 11560-11564. doi: 10.1158/0008-5472.CAN-06-1950 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Necrosis Factor- Is a Potent Endogenous Mutagen that Promotes Cellular Transformation

Bin Yan, Huili Wang, Zahid N. Rabbani, Yulin Zhao, Wenrong Li, Yuqing Yuan, Fang Li, Mark W. Dewhirst, and Chuan-Yuan Li
Cancer Res 2006 66: 11565-11570. doi: 10.1158/0008-5472.CAN-06-2540 [Abstract] [Full Text] [PDF] Supplementary Data  

Adrenal Hyperplasia and Adenomas Are Associated with Inhibition of Phosphodiesterase 11A in Carriers of PDE11A Sequence Variants That Are Frequent in the Population

Anelia Horvath, Christoforos Giatzakis, Audrey Robinson-White, Sosipatros Boikos, Elizabeth Levine, Kurt Griffin, Erica Stein, Virginia Kamvissi, Payal Soni, Ioannis Bossis, Wouter de Herder, J. Aidan Carney, Jérôme Bertherat, Peter K. Gregersen, Elaine F. Remmers, and Constantine A. Stratakis
Cancer Res 2006 66: 11571-11575. doi: 10.1158/0008-5472.CAN-06-2914 [Abstract] [Full Text] [PDF] Supplementary Data  

Activated Checkpoint Kinase 2 Provides a Survival Signal for Tumor Cells

Jagadish C. Ghosh, Takehiko Dohi, Christopher M. Raskett, Timothy F. Kowalik, and Dario C. Altieri
Cancer Res 2006 66: 11576-11579. doi: 10.1158/0008-5472.CAN-06-3095 [Abstract] [Full Text] [PDF] Supplementary Data  

Nrf2-Deficient Mice Have an Increased Susceptibility to Dextran Sulfate Sodium–Induced Colitis

Tin Oo Khor, Mou-Tuan Huang, Ki Han Kwon, Jefferson Y. Chan, Bandaru S. Reddy, and Ah-Ng Kong
Cancer Res 2006 66: 11580-11584. doi: 10.1158/0008-5472.CAN-06-3562 [Abstract] [Full Text] [PDF]  

Physical Association with WWOX Suppresses c-Jun Transcriptional Activity

Eugenio Gaudio, Alexey Palamarchuk, Tiziana Palumbo, Francesco Trapasso, Yuri Pekarsky, Carlo M. Croce, and Rami I. Aqeilan
Cancer Res 2006 66: 11585-11589. doi: 10.1158/0008-5472.CAN-06-3376 [Abstract] [Full Text] [PDF]  

Tcl1 Expression in Chronic Lymphocytic Leukemia Is Regulated by miR-29 and miR-181

Yuri Pekarsky, Urmila Santanam, Amelia Cimmino, Alexey Palamarchuk, Alexey Efanov, Vadim Maximov, Stefano Volinia, Hansjuerg Alder, Chang-Gong Liu, Laura Rassenti, George A. Calin, John P. Hagan, Thomas Kipps, and Carlo M. Croce
Cancer Res 2006 66: 11590-11593. doi: 10.1158/0008-5472.CAN-06-3613 [Abstract] [Full Text] [PDF]  

KAP1, a Novel Substrate for PIKK Family Members, Colocalizes with Numerous Damage Response Factors at DNA Lesions

David E. White, Dmitri Negorev, Hongzhuang Peng, Alexey V. Ivanov, Gerd G. Maul, and Frank J. Rauscher, III
Cancer Res 2006 66: 11594-11599. doi: 10.1158/0008-5472.CAN-06-4138 [Abstract] [Full Text] [PDF]  

Asbestos Redirects Nitric Oxide Signaling through Rapid Catalytic Conversion to Nitrite

Douglas D. Thomas, Michael G. Espey, Derek A. Pociask, Lisa A. Ridnour, Sonia Donzelli, and David A. Wink
Cancer Res 2006 66: 11600-11604. doi: 10.1158/0008-5472.CAN-06-1140 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Comparison of Kinome Profiles of Barrett's Esophagus with Normal Squamous Esophagus and Normal Gastric Cardia

Jantine W.P.M. van Baal, Sander H. Diks, Ronald J.A. Wanders, Agnieskza M. Rygiel, Francesca Milano, Jos Joore, Jacques J.G.H.M. Bergman, Maikel P. Peppelenbosch, and Kausilia K. Krishnadath
Cancer Res 2006 66: 11605-11612. doi: 10.1158/0008-5472.CAN-06-1370 [Abstract] [Full Text] [PDF] Supplementary Data  

HMGA1 Is a Determinant of Cellular Invasiveness and In vivo Metastatic Potential in Pancreatic Adenocarcinoma

Siong-Seng Liau, Amarsanaa Jazag, and Edward E. Whang
Cancer Res 2006 66: 11613-11622. doi: 10.1158/0008-5472.CAN-06-1460 [Abstract] [Full Text] [PDF]  

Up-regulation of GPR48 Induced by Down-regulation of p27^Kip1 Enhances Carcinoma Cell Invasiveness and Metastasis

Yun Gao, Kyoko Kitagawa, Yoshihiro Hiramatsu, Hirotoshi Kikuchi, Tomoyasu Isobe, Mai Shimada, Chiharu Uchida, Takayuki Hattori, Toshiaki Oda, Keiko Nakayama, Keiichi I. Nakayama, Tatsuo Tanaka, Hiroyuki Konno, and Masatoshi Kitagawa
Cancer Res 2006 66: 11623-11631. doi: 10.1158/0008-5472.CAN-06-2629 [Abstract] [Full Text] [PDF] Supplementary Data  

Multiple Interacting Oncogenes on the 8p11-p12 Amplicon in Human Breast Cancer

Zeng Quan Yang, Katie L. Streicher, Michael E. Ray, Judith Abrams, and Stephen P. Ethier
Cancer Res 2006 66: 11632-11643. doi: 10.1158/0008-5472.CAN-06-2946 [Abstract] [Full Text] [PDF]  

Matrix Metalloproteinase Polymorphisms and Bladder Cancer Risk

A. Karim Kader, Lina Shao, Colin P. Dinney, Matthew B. Schabath, Yunfei Wang, Jun Liu, Jian Gu, H. Barton Grossman, and Xifeng Wu
Cancer Res 2006 66: 11644-11648. doi: 10.1158/0008-5472.CAN-06-1212 [Abstract] [Full Text] [PDF]  

Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression

Chuanwei Yang, Sally Trent, Viviana Ionescu-Tiba, Lan Lan, Toshi Shioda, Dennis Sgroi, and Emmett V. Schmidt
Cancer Res 2006 66: 11649-11658. doi: 10.1158/0008-5472.CAN-06-1645 [Abstract] [Full Text] [PDF] Supplementary Data  

DNA Methylation Pathway Alterations in an Autochthonous Murine Model of Prostate Cancer

Shannon R. Morey, Dominic J. Smiraglia, Smitha R. James, Jihnhee Yu, Michael T. Moser, Barbara A. Foster, and Adam R. Karpf
Cancer Res 2006 66: 11659-11667. doi: 10.1158/0008-5472.CAN-06-1937 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of DNA Methyltransferase 1 by EBV LMP1 Involves c-Jun NH₂-Terminal Kinase Signaling

Chia-Lung Tsai, Hsin-Pai Li, Yen-Jung Lu, Chuen Hsueh, Ying Liang, Chi-Long Chen, Sai Wah Tsao, Ka-Po Tse, Jau-Song Yu, and Yu-Sun Chang
Cancer Res 2006 66: 11668-11676. doi: 10.1158/0008-5472.CAN-06-2194 [Abstract] [Full Text] [PDF] Supplementary Data  

Nuclear Localization of PTEN Is Regulated by Ca²⁺ through a Tyrosil Phosphorylation–Independent Conformational Modification in Major Vault Protein

Takeo Minaguchi, Kristin A. Waite, and Charis Eng
Cancer Res 2006 66: 11677-11682. doi: 10.1158/0008-5472.CAN-06-2240 [Abstract] [Full Text] [PDF]  

Reduced Repair of the Oxidative 8-Oxoguanine DNA Damage and Risk of Head and Neck Cancer

Tamar Paz-Elizur, Rami Ben-Yosef, Dalia Elinger, Akiva Vexler, Meir Krupsky, Alain Berrebi, Adi Shani, Edna Schechtman, Laurence Freedman, and Zvi Livneh
Cancer Res 2006 66: 11683-11689. doi: 10.1158/0008-5472.CAN-06-2294 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Amplification and Overexpression of CTTN (EMS1) Contribute to the Metastasis of Esophageal Squamous Cell Carcinoma by Promoting Cell Migration and Anoikis Resistance

Man-Li Luo, Xiao-Ming Shen, Yu Zhang, Fang Wei, Xin Xu, Yan Cai, Xun Zhang, Yun-Tian Sun, Qi-Min Zhan, Min Wu, and Ming-Rong Wang
Cancer Res 2006 66: 11690-11699. doi: 10.1158/0008-5472.CAN-06-1484 [Abstract] [Full Text] [PDF] Supplementary Data  

RhoA Mediates Cyclooxygenase-2 Signaling to Disrupt the Formation of Adherens Junctions and Increase Cell Motility

Yu-Wen E. Chang, Jerry W. Marlin, Terry W. Chance, and Rolf Jakobi
Cancer Res 2006 66: 11700-11708. doi: 10.1158/0008-5472.CAN-06-1818 [Abstract] [Full Text] [PDF]  

A Ras Inhibitor Tilts the Balance between Rac and Rho and Blocks Phosphatidylinositol 3-Kinase–Dependent Glioblastoma Cell Migration

Liat Goldberg and Yoel Kloog
Cancer Res 2006 66: 11709-11717. doi: 10.1158/0008-5472.CAN-06-1878 [Abstract] [Full Text] [PDF]  

A Specific Role for AKT3 in the Genesis of Ovarian Cancer through Modulation of G₂-M Phase Transition

Briony E. Cristiano, Joanna C. Chan, Katherine M. Hannan, Nicole A. Lundie, Nelly J. Marmy-Conus, Ian G. Campbell, Wayne A. Phillips, Melissa Robbie, Ross D. Hannan, and Richard B. Pearson
Cancer Res 2006 66: 11718-11725. doi: 10.1158/0008-5472.CAN-06-1968 [Abstract] [Full Text] [PDF] Supplementary Data  

Ectopic Doublecortin Gene Expression Suppresses the Malignant Phenotype in Glioblastoma Cells

Manoranjan Santra, Xuepeng Zhang, Sutapa Santra, Feng Jiang, and Michael Chopp
Cancer Res 2006 66: 11726-11735. doi: 10.1158/0008-5472.CAN-06-1978 [Abstract] [Full Text] [PDF]  

Preconditioning of the Tumor Vasculature and Tumor Cells by Intermittent Hypoxia: Implications for Anticancer Therapies

Philippe Martinive, Florence Defresne, Caroline Bouzin, Julie Saliez, Florence Lair, Vincent Grégoire, Carine Michiels, Chantal Dessy, and Olivier Feron
Cancer Res 2006 66: 11736-11744. doi: 10.1158/0008-5472.CAN-06-2056 [Abstract] [Full Text] [PDF]  

Collagen I Promotes Metastasis in Pancreatic Cancer by Activating c-Jun NH₂-Terminal Kinase 1 and Up-regulating N-Cadherin Expression

Yasushi Shintani, Michael A. Hollingsworth, Margaret J. Wheelock, and Keith R. Johnson
Cancer Res 2006 66: 11745-11753. doi: 10.1158/0008-5472.CAN-06-2322 [Abstract] [Full Text] [PDF] Supplementary Data  

Calmodulin-Androgen Receptor (AR) Interaction: Calcium-Dependent, Calpain-Mediated Breakdown of AR in LNCaP Prostate Cancer Cells

Ronald P. Pelley, Kannagi Chinnakannu, Shalini Murthy, Faith M. Strickland, Mani Menon, Q. Ping Dou, Evelyn R. Barrack, and G. Prem-Veer Reddy
Cancer Res 2006 66: 11754-11762. doi: 10.1158/0008-5472.CAN-06-2918 [Abstract] [Full Text] [PDF]  

Human Kallikrein 8 Protease Confers a Favorable Clinical Outcome in Non–Small Cell Lung Cancer by Suppressing Tumor Cell Invasiveness

Yuh-Pyng Sher, Cheng-Chung Chou, Ruey-Hwang Chou, Han-Ming Wu, Wun-Shaing Wayne Chang, Chun-Houh Chen, Pan-Chyr Yang, Cheng-Wen Wu, Chia-Li Yu, and Konan Peck
Cancer Res 2006 66: 11763-11770. doi: 10.1158/0008-5472.CAN-06-3165 [Abstract] [Full Text] [PDF] Supplementary Data  

Tenascin-C Stimulates Glioma Cell Invasion through Matrix Metalloproteinase-12

Susobhan Sarkar, Robert K. Nuttall, Shuhong Liu, Dylan R. Edwards, and V. Wee Yong
Cancer Res 2006 66: 11771-11780. doi: 10.1158/0008-5472.CAN-05-0470 [Abstract] [Full Text] [PDF] Supplementary Data  

Enforced Expression of NUP98-HOXA9 in Human CD34⁺ Cells Enhances Stem Cell Proliferation

Ki Y. Chung, Giovanni Morrone, Jan Jacob Schuringa, Magdalena Plasilova, Jae-Hung Shieh, Yue Zhang, Pengbo Zhou, and Malcolm A.S. Moore
Cancer Res 2006 66: 11781-11791. doi: 10.1158/0008-5472.CAN-06-0706 [Abstract] [Full Text] [PDF]  

Androgens Regulate Protein Kinase C Transcription and Modulate Its Apoptotic Function in Prostate Cancer Cells

M. Veronica Gavrielides, Anatilde M. Gonzalez-Guerrico, Natalia A. Riobo, and Marcelo G. Kazanietz
Cancer Res 2006 66: 11792-11801. doi: 10.1158/0008-5472.CAN-06-1139 [Abstract] [Full Text] [PDF]  

Endothelins Induce CCR7 Expression by Breast Tumor Cells via Endothelin Receptor A and Hypoxia-Inducible Factor-1

Julia L. Wilson, Joy Burchell, and Matthew J. Grimshaw
Cancer Res 2006 66: 11802-11807. doi: 10.1158/0008-5472.CAN-06-1222 [Abstract] [Full Text] [PDF]  

G-Quadruplexes Induce Apoptosis in Tumor Cells

Haiyan Qi, Chao-Po Lin, Xuan Fu, Laurence M. Wood, Angela A. Liu, Yuan-Chin Tsai, Yongjie Chen, Christopher M. Barbieri, Daniel S. Pilch, and Leroy F. Liu
Cancer Res 2006 66: 11808-11816. doi: 10.1158/0008-5472.CAN-06-1225 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

Activation of p53 in Cervical Cancer Cells by Human Papillomavirus E6 RNA Interference Is Transient, but Can Be Sustained by Inhibiting Endogenous Nuclear Export–Dependent p53 Antagonists

Riku Koivusalo, Antoine Mialon, Hanna Pitkänen, Jukka Westermarck, and Sakari Hietanen
Cancer Res 2006 66: 11817-11824. doi: 10.1158/0008-5472.CAN-06-2185 [Abstract] [Full Text] [PDF]  

Proteomic Profiling of Primary Breast Cancer Predicts Axillary Lymph Node Metastasis

Taku Nakagawa, Sharon K. Huang, Steve R. Martinez, Andy N. Tran, David Elashoff, Xing Ye, Roderick R. Turner, Armando E. Giuliano, and Dave S.B. Hoon
Cancer Res 2006 66: 11825-11830. doi: 10.1158/0008-5472.CAN-06-2337 [Abstract] [Full Text] [PDF]  

Cross-talk between G Protein–Coupled Receptor and Epidermal Growth Factor Receptor Signaling Pathways Contributes to Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Sufi Mary Thomas, Neil E. Bhola, Qing Zhang, Sarah C. Contrucci, Abbey L. Wentzel, Maria L. Freilino, William E. Gooding, Jill M. Siegfried, Daniel C. Chan, and Jennifer Rubin Grandis
Cancer Res 2006 66: 11831-11839. doi: 10.1158/0008-5472.CAN-06-2876 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Retargeted Oncolytic Measles Strains Entering via the EGFRvIII Receptor Maintain Significant Antitumor Activity against Gliomas with Increased Tumor Specificity

Cory Allen, Sompong Vongpunsawad, Takafumi Nakamura, C. David James, Mark Schroeder, Roberto Cattaneo, Caterina Giannini, James Krempski, Kah-Whye Peng, Jenny M. Goble, Joon H. Uhm, Stephen J. Russell, and Evanthia Galanis
Cancer Res 2006 66: 11840-11850. doi: 10.1158/0008-5472.CAN-06-1200 [Abstract] [Full Text] [PDF] Supplementary Data  

Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5

Li Liu, Yichen Cao, Charles Chen, Xiaomei Zhang, Angela McNabola, Dean Wilkie, Scott Wilhelm, Mark Lynch, and Christopher Carter
Cancer Res 2006 66: 11851-11858. doi: 10.1158/0008-5472.CAN-06-1377 [Abstract] [Full Text] [PDF]  

Cross-talk between Peroxisome Proliferator-Activated Receptor and Cytosolic Phospholipase A₂/Cyclooxygenase-2/Prostaglandin E₂ Signaling Pathways in Human Hepatocellular Carcinoma Cells

Lihong Xu, Chang Han, Kyu Lim, and Tong Wu
Cancer Res 2006 66: 11859-11868. doi: 10.1158/0008-5472.CAN-06-1445 [Abstract] [Full Text] [PDF]  

N-Glycosylation of MDA-7/IL-24 Is Dispensable for Tumor Cell–Specific Apoptosis and "Bystander" Antitumor Activity

Moira Sauane, Pankaj Gupta, Irina V. Lebedeva, Zao-zhong Su, Devanand Sarkar, Aaron Randolph, Kristoffer Valerie, Rahul V. Gopalkrishnan, and Paul B. Fisher
Cancer Res 2006 66: 11869-11877. doi: 10.1158/0008-5472.CAN-06-1887 [Abstract] [Full Text] [PDF]  

Cationic Albumin–Conjugated Pegylated Nanoparticles Allow Gene Delivery into Brain Tumors via Intravenous Administration

Wei Lu, Qing Sun, Jin Wan, Zhenjue She, and Xin-Guo Jiang
Cancer Res 2006 66: 11878-11887. doi: 10.1158/0008-5472.CAN-06-2354 [Abstract] [Full Text] [PDF] Supplementary Data  

Dimethylfumarate Impairs Melanoma Growth and Metastasis

Robert Loewe, Teresa Valero, Silvia Kremling, Barbara Pratscher, Rainer Kunstfeld, Hubert Pehamberger, and Peter Petzelbauer
Cancer Res 2006 66: 11888-11896. doi: 10.1158/0008-5472.CAN-06-2397 [Abstract] [Full Text] [PDF] Supplementary Data  

Elevated E2F1 Inhibits Transcription of the Androgen Receptor in Metastatic Hormone-Resistant Prostate Cancer

Joanne N. Davis, Kirk J. Wojno, Stephanie Daignault, Matthias D. Hofer, Rainer Kuefer, Mark A. Rubin, and Mark L. Day
Cancer Res 2006 66: 11897-11906. doi: 10.1158/0008-5472.CAN-06-2497 [Abstract] [Full Text] [PDF]  

Tumor-Suppressive Effects of MBP-1 in Non–Small Cell Lung Cancer Cells

Asish K. Ghosh, Robert Steele, Jan Ryerse, and Ratna B. Ray
Cancer Res 2006 66: 11907-11912. doi: 10.1158/0008-5472.CAN-06-2754 [Abstract] [Full Text] [PDF]  

Dendrimer-Encapsulated Camptothecins: Increased Solubility, Cellular Uptake, and Cellular Retention Affords Enhanced Anticancer Activity In vitro

Meredith T. Morgan, Yuka Nakanishi, David J. Kroll, Aaron P. Griset, Michael A. Carnahan, Michel Wathier, Nicholas H. Oberlies, Govindarajan Manikumar, Mansukh C. Wani, and Mark W. Grinstaff
Cancer Res 2006 66: 11913-11921. doi: 10.1158/0008-5472.CAN-06-2066 [Abstract] [Full Text] [PDF]  

A Novel Pathway Involving Melanoma Differentiation Associated Gene-7/Interleukin-24 Mediates Nonsteroidal Anti-inflammatory Drug–Induced Apoptosis and Growth Arrest of Cancer Cells

Luiz F. Zerbini, Akos Czibere, Yihong Wang, Ricardo G. Correa, Hasan Otu, Marie Joseph, Yuko Takayasu, Moriah Silver, Xuesong Gu, Kriangsak Ruchusatsawat, Linglin Li, Devanand Sarkar, Jin-Rong Zhou, Paul B. Fisher, and Towia A. Libermann
Cancer Res 2006 66: 11922-11931. doi: 10.1158/0008-5472.CAN-06-2068 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocytic Ark/Prk Kinases Play a Critical Role in Adriamycin Resistance in Both Yeast and Mammalian Cells

Tsutomu Takahashi, Takemitsu Furuchi, and Akira Naganuma
Cancer Res 2006 66: 11932-11937. doi: 10.1158/0008-5472.CAN-06-3220 [Abstract] [Full Text] [PDF]  

DNA Damage by Benzo(a)pyrene in Human Cells Is Increased by Cigarette Smoke and Decreased by a Filter Containing Rosemary Extract, Which Lowers Free Radicals

Kroum Alexandrov, Margarita Rojas, and Christian Rolando
Cancer Res 2006 66: 11938-11945. doi: 10.1158/0008-5472.CAN-06-3277 [Abstract] [Full Text] [PDF]  

Immunology:

Therapeutic Expression of an Anti-Death Receptor 5 Single-Chain Fixed-Variable Region Prevents Tumor Growth in Mice

Juan Shi, Yanxin Liu, Yong Zheng, Yabin Guo, Jinchun Zhang, Pik-to Cheung, Ruian Xu, and Dexian Zheng
Cancer Res 2006 66: 11946-11953. doi: 10.1158/0008-5472.CAN-06-1227 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Diverse Gene Expression and DNA Methylation Profiles Correlate with Differential Adaptation of Breast Cancer Cells to the Antiestrogens Tamoxifen and Fulvestrant

Meiyun Fan, Pearlly S. Yan, Cori Hartman-Frey, Lei Chen, Henry Paik, Samuel L. Oyer, Jonathan D. Salisbury, Alfred S.L. Cheng, Lang Li, Phillip H. Abbosh, Tim H-M. Huang, and Kenneth P. Nephew
Cancer Res 2006 66: 11954-11966. doi: 10.1158/0008-5472.CAN-06-1666 [Abstract] [Full Text] [PDF] Supplementary Data  

Mammary-Specific Ron Receptor Overexpression Induces Highly Metastatic Mammary Tumors Associated with ß-Catenin Activation

Glendon M. Zinser, Mike A. Leonis, Kenya Toney, Peterson Pathrose, Megan Thobe, Sarah A. Kader, Belinda E. Peace, Shirelyn R. Beauman, Margaret H. Collins, and Susan E. Waltz
Cancer Res 2006 66: 11967-11974. doi: 10.1158/0008-5472.CAN-06-2473 [Abstract] [Full Text] [PDF]  

Peroxisome Proliferator-Activated Receptor Is a Zac Target Gene Mediating Zac Antiproliferation

Thomas Barz, Anke Hoffmann, Markus Panhuysen, and Dietmar Spengler
Cancer Res 2006 66: 11975-11982. doi: 10.1158/0008-5472.CAN-06-1529 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

The Tumor Metastasis Suppressor Gene Drg-1 Down-regulates the Expression of Activating Transcription Factor 3 in Prostate Cancer

Sucharita Bandyopadhyay, Ying Wang, Rui Zhan, Sudha K. Pai, Misako Watabe, Megumi Iiizumi, Eiji Furuta, Sonia Mohinta, Wen Liu, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Yukio Takano, Ken Saito, Therese Commes, David Piquemal, Tsonwin Hai, and Kounosuke Watabe
Cancer Res 2006 66: 11983-11990. doi: 10.1158/0008-5472.CAN-06-0943 [Abstract] [Full Text] [PDF]  

Antitumor Effect of 2-Methoxyestradiol in a Rat Orthotopic Brain Tumor Model

Seung-Hee Kang, Heidi T. Cho, Sarojini Devi, Zhaobin Zhang, Daniel Escuin, Zhongxing Liang, Hui Mao, Daniel J. Brat, Jeffrey J. Olson, Jonathan W. Simons, Theresa M. LaVallee, Paraskevi Giannakakou, Erwin G. Van Meir, and Hyunsuk Shim
Cancer Res 2006 66: 11991-11997. doi: 10.1158/0008-5472.CAN-06-1320 [Abstract] [Full Text] [PDF]  

Mitogenic Action of the Androgen Receptor Sensitizes Prostate Cancer Cells to Taxane-Based Cytotoxic Insult

Janet K. Hess-Wilson, Hannah K. Daly, William A. Zagorski, Christopher P. Montville, and Karen E. Knudsen
Cancer Res 2006 66: 11998-12008. doi: 10.1158/0008-5472.CAN-06-2249 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Identification of Biomarkers Modulated by the Rexinoid LGD1069 (Bexarotene) in Human Breast Cells Using Oligonucleotide Arrays

Hee-Tae Kim, Gu Kong, David DeNardo, Yuxin Li, Ivan Uray, Sunita Pal, Syed Mohsin, Susan G. Hilsenbeck, Reid Bissonnette, William W. Lamph, Karen Johnson, and Powel H. Brown
Cancer Res 2006 66: 12009-12018. doi: 10.1158/0008-5472.CAN-05-2515 [Abstract] [Full Text] [PDF] Supplementary Data  

A Systematic Assessment of Common Genetic Variation in CYP11A and Risk of Breast Cancer

Veronica Wendy Setiawan, Iona Cheng, Daniel O. Stram, Elena Giorgi, Malcolm C. Pike, David Van Den Berg, Loreall Pooler, Noel P. Burtt, Loic Le Marchand, David Altshuler, Joel Hirschhorn, Brian E. Henderson, and Christopher A. Haiman
Cancer Res 2006 66: 12019-12025. doi: 10.1158/0008-5472.CAN-06-1101 [Abstract] [Full Text] [PDF] Supplementary Data  

Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus bisporus)

Shiuan Chen, Sei-Ryang Oh, Sheryl Phung, Gene Hur, Jing Jing Ye, Sum Ling Kwok, Gayle E. Shrode, Martha Belury, Lynn S. Adams, and Dudley Williams
Cancer Res 2006 66: 12026-12034. doi: 10.1158/0008-5472.CAN-06-2206 [Abstract] [Full Text] [PDF]  

Obituaries:

Howard Earle Skipper: In Memoriam (1915–2006)

Linda Simpson-Herren and Glynn P. Wheeler
Cancer Res 2006 66: 12035-12036. doi: 10.1158/0008-5472.CAN-06-3615 [Full Text] [PDF]  

Joseph H. Burchenal: In Memoriam (1912–2006)

Cancer Res 2006 66: 12037-12038. doi: 10.1158/0008-5472.CAN-06-3943 [Full Text] [PDF]  

Correction:

MEN1 Interacts with CHES1 in DNA Damage Response

Cancer Res 2006 66: 12039 [Full Text] [PDF]  

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