Reviews:

Oxidative Damage and Aging: Spotlight on Mitochondria

Nancy J. Linford, Samuel E. Schriner, and Peter S. Rabinovitch
Cancer Res 2006 66: 2497-2499. [Abstract] [Full Text] [PDF]  

Targeting Multiple Signaling Pathways by Green Tea Polyphenol (–)-Epigallocatechin-3-Gallate

Naghma Khan, Farrukh Afaq, Mohammad Saleem, Nihal Ahmad, and Hasan Mukhtar
Cancer Res 2006 66: 2500-2505. [Abstract] [Full Text] [PDF]  

From Integrated Genomics to Tumor Lineage Dependency

Levi A. Garraway and William R. Sellers
Cancer Res 2006 66: 2506-2508. [Abstract] [Full Text] [PDF]  

Priority Reports:

Degradation of Fibrillar Collagen in a Human Melanoma Xenograft Improves the Efficacy of an Oncolytic Herpes Simplex Virus Vector

Trevor D. McKee, Paola Grandi, Wilson Mok, George Alexandrakis, Numpon Insin, John P. Zimmer, Moungi G. Bawendi, Yves Boucher, Xandra O. Breakefield, and Rakesh K. Jain
Cancer Res 2006 66: 2509-2513. [Abstract] [Full Text] [PDF] Supplementary Data  

Chromosomal Instability in MYH- and APC-Mutant Adenomatous Polyps

Joana Cardoso, Lia Molenaar, Renee X. de Menezes, Monique van Leerdam, Carla Rosenberg, Gabriela Möslein, Julian Sampson, Hans Morreau, Judith M. Boer, and Riccardo Fodde
Cancer Res 2006 66: 2514-2519. [Abstract] [Full Text] [PDF] Supplementary Data  

Proteolytic Release of Soluble UL16-Binding Protein 2 from Tumor Cells

Inja Waldhauer and Alexander Steinle
Cancer Res 2006 66: 2520-2526. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-1 Is Overexpressed in Multiple Genetically Engineered Mouse Models of Epithelial Ovarian Cancer

Takiko Daikoku, Susanne Tranguch, Irina N. Trofimova, Daniela M. Dinulescu, Tyler Jacks, Alexander Yu. Nikitin, Denise C. Connolly, and Sudhansu K. Dey
Cancer Res 2006 66: 2527-2531. [Abstract] [Full Text] [PDF] Supplementary Data  

Caspase Recruitment Domain-Containing Protein 15 Mutations in Patients with Colorectal Cancer

Rebecca L. Roberts, Richard B. Gearry, Melanie D.E. Allington, Helen R. Morrin, Bridget A. Robinson, and Frank A. Frizelle
Cancer Res 2006 66: 2532-2535. [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Haploinsufficiency of the Hmga1 Gene Causes Cardiac Hypertrophy and Myelo-Lymphoproliferative Disorders in Mice

Monica Fedele, Vincenzo Fidanza, Sabrina Battista, Francesca Pentimalli, Andres J.P. Klein-Szanto, Rosa Visone, Ivana De Martino, Antonio Curcio, Carmine Morisco, Luigi Del Vecchio, Gustavo Baldassarre, Claudio Arra, Giuseppe Viglietto, Ciro Indolfi, Carlo M. Croce, and Alfredo Fusco
Cancer Res 2006 66: 2536-2543. [Abstract] [Full Text] [PDF] Supplementary Data  

Cyclin D1 Is Transcriptionally Regulated by and Required for Transformation by Activated Signal Transducer and Activator of Transcription 3

Kenneth Leslie, Cynthia Lang, Geeta Devgan, Janeen Azare, Marjan Berishaj, William Gerald, Young Bae Kim, Keren Paz, James E. Darnell, Christopher Albanese, Toshiyuki Sakamaki, Richard Pestell, and Jacqueline Bromberg
Cancer Res 2006 66: 2544-2552. [Abstract] [Full Text] [PDF]  

Knockdown of Contactin-1 Expression Suppresses Invasion and Metastasis of Lung Adenocarcinoma

Jen-Liang Su, Ching-Yao Yang, Jin-Yuan Shih, Lin-Hung Wei, Chang-Yao Hsieh, Yung-Ming Jeng, Ming-Yang Wang, Pan-Chyr Yang, and Min-Liang Kuo
Cancer Res 2006 66: 2553-2561. [Abstract] [Full Text] [PDF] Supplementary Data  

Role of the Tumor Suppressor RASSF1A in Mst1-Mediated Apoptosis

Hyun Jung Oh, Kyung-Kwon Lee, Su Jung Song, Mi Sun Jin, Min Sup Song, Joo Hyun Lee, Chang Rak Im, Jie-Oh Lee, Shin Yonehara, and Dae-Sik Lim
Cancer Res 2006 66: 2562-2569. [Abstract] [Full Text] [PDF]  

7,12-Dimethylbenz(a)Anthracene Treatment of a c-rel Mouse Mammary Tumor Cell Line Induces Epithelial to Mesenchymal Transition via Activation of Nuclear Factor-B

Sangmin Ryan Shin, Nuria Sánchez-Velar, David H. Sherr, and Gail E. Sonenshein
Cancer Res 2006 66: 2570-2575. [Abstract] [Full Text] [PDF]  

Renal Cyst Development in Mice with Conditional Inactivation of the von Hippel-Lindau Tumor Suppressor

Erinn B. Rankin, John E. Tomaszewski, and Volker H. Haase
Cancer Res 2006 66: 2576-2583. [Abstract] [Full Text] [PDF]  

Large-Scale Molecular Comparison of Human Schwann Cells to Malignant Peripheral Nerve Sheath Tumor Cell Lines and Tissues

Shyra J. Miller, Fatima Rangwala, Jon Williams, Peter Ackerman, Sue Kong, Anil G. Jegga, Sergio Kaiser, Bruce J. Aronow, Silke Frahm, Lan Kluwe, Victor Mautner, Meena Upadhyaya, David Muir, Margaret Wallace, Jussara Hagen, Dawn E. Quelle, Mark A. Watson, Arie Perry, David H. Gutmann, and Nancy Ratner
Cancer Res 2006 66: 2584-2591. [Abstract] [Full Text] [PDF] Supplementary Data  

Fibrinogen Overexpression in Pancreatic Cancer Identified by Large-scale Proteomic Analysis of Serum Samples

Mark Bloomston, Jeff X. Zhou, Alexander S. Rosemurgy, Wendy Frankel, Carlos A. Muro-Cacho, and Timothy J. Yeatman
Cancer Res 2006 66: 2592-2599. [Abstract] [Full Text] [PDF]  

Normoxic Stabilization of Hypoxia-Inducible Factor-1 by Modulation of the Labile Iron Pool in Differentiating U937 Macrophages: Effect of Natural Resistance–Associated Macrophage Protein 1

Helen J. Knowles, David R. Mole, Peter J. Ratcliffe, and Adrian L. Harris
Cancer Res 2006 66: 2600-2607. [Abstract] [Full Text] [PDF]  

Induction of Nevi and Skin Tumors in Ink4a/Arf Xpa Knockout Mice by Neonatal, Intermittent, or Chronic UVB Exposures

Arne van Schanke, Gemma M.C.A.L. van Venrooij, Marjan J. Jongsma, H. Alexander Banus, Leon H.F. Mullenders, Henk J. van Kranen, and Frank R. de Gruijl
Cancer Res 2006 66: 2608-2615. [Abstract] [Full Text] [PDF]  

Activation of Human Long Interspersed Nuclear Element 1 Retrotransposition by Benzo(a)pyrene, an Ubiquitous Environmental Carcinogen

Vilius Stribinskis and Kenneth S. Ramos
Cancer Res 2006 66: 2616-2620. [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Fibulins 3 and 5 Antagonize Tumor Angiogenesis In vivo

Allan R. Albig, Jason R. Neil, and William P. Schiemann
Cancer Res 2006 66: 2621-2629. [Abstract] [Full Text] [PDF]  

Interleukin-23–Expressing Bone Marrow–Derived Neural Stem-Like Cells Exhibit Antitumor Activity against Intracranial Glioma

Xiangpeng Yuan, Jinwei Hu, Maria L. Belladonna, Keith L. Black, and John S. Yu
Cancer Res 2006 66: 2630-2638. [Abstract] [Full Text] [PDF]  

Antiangiogenic Therapy Decreases Integrin Expression in Normalized Tumor Blood Vessels

Virginia J. Yao, Michael G. Ozawa, Amanda S. Varner, Ian M. Kasman, Yvan H. Chanthery, Renata Pasqualini, Wadih Arap, and Donald M. McDonald
Cancer Res 2006 66: 2639-2649. [Abstract] [Full Text] [PDF]  

Inhibition of VEGFR-3 Activation with the Antagonistic Antibody More Potently Suppresses Lymph Node and Distant Metastases than Inactivation of VEGFR-2

Nicole Roberts, Bryan Kloos, Melanie Cassella, Simona Podgrabinska, Kris Persaud, Yan Wu, Bronislaw Pytowski, and Mihaela Skobe
Cancer Res 2006 66: 2650-2657. [Abstract] [Full Text] [PDF]  

Tumor-Derived Cyr61(CCN1) Promotes Stromal Matrix Metalloproteinase-1 Production and Protease-Activated Receptor 1–Dependent Migration of Breast Cancer Cells

Nga Nguyen, Athan Kuliopulos, Roger A. Graham, and Lidija Covic
Cancer Res 2006 66: 2658-2665. [Abstract] [Full Text] [PDF] Supplementary Data  

N-myc Can Substitute for Insulin-Like Growth Factor Signaling in a Mouse Model of Sonic Hedgehog–Induced Medulloblastoma

Samuel R. Browd, Anna M. Kenney, Oren N. Gottfried, Joon Won Yoon, David Walterhouse, Carolyn A. Pedone, and Daniel W. Fults
Cancer Res 2006 66: 2666-2672. [Abstract] [Full Text] [PDF]  

Hepatocyte Growth Factor and Inducible Nitric Oxide Synthase Are Involved in Multidrug Resistance–Induced Angiogenesis in Hepatocellular Carcinoma Cell Lines

Nadia Lasagna, Ornella Fantappiè, Michela Solazzo, Lucia Morbidelli, Serena Marchetti, Greta Cipriani, Marina Ziche, and Roberto Mazzanti
Cancer Res 2006 66: 2673-2682. [Abstract] [Full Text] [PDF]  

FHIT Is Up-Regulated by Inflammatory Stimuli and Inhibits Prostaglandin E₂–Mediated Cancer Progression

Koshi Mimori, Hideshi Ishii, Hisashi Nagahara, Tomoya Sudo, Keishi Yamashita, Hiroshi Inoue, Graham F. Barnard, and Masaki Mori
Cancer Res 2006 66: 2683-2690. [Abstract] [Full Text] [PDF]  

Matrix Metalloproteinases Play an Active Role in Wnt1-Induced Mammary Tumorigenesis

Laurence Blavier, Alisa Lazaryev, Frederick Dorey, Gregory M. Shackleford, and Yves A. DeClerck
Cancer Res 2006 66: 2691-2699. [Abstract] [Full Text] [PDF]  

p44 Mitogen-Activated Protein Kinase (Extracellular Signal-Regulated Kinase 1)–Dependent Signaling Contributes to Epithelial Skin Carcinogenesis

Christine Bourcier, Arnaud Jacquel, Jochen Hess, Isabelle Peyrottes, Peter Angel, Paul Hofman, Patrick Auberger, Jacques Pouysségur, and Gilles Pagès
Cancer Res 2006 66: 2700-2707. [Abstract] [Full Text] [PDF]  

Phosphorylation of Ezrin by Cyclin-Dependent Kinase 5 Induces the Release of Rho GDP Dissociation Inhibitor to Inhibit Rac1 Activity in Senescent Cells

Hi-Su Yang and Philip W. Hinds
Cancer Res 2006 66: 2708-2715. [Abstract] [Full Text] [PDF]  

Matrix Metalloproteinase 26 Proteolysis of the NH₂-Terminal Domain of the Estrogen Receptor ß Correlates with the Survival of Breast Cancer Patients

Alexei Y. Savinov, Albert G. Remacle, Vladislav S. Golubkov, Maryla Krajewska, Susan Kennedy, Michael J. Duffy, Dmitri V. Rozanov, Stan Krajewski, and Alex Y. Strongin
Cancer Res 2006 66: 2716-2724. [Abstract] [Full Text] [PDF]  

Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B

Balaji Krishnamachary, David Zagzag, Hideko Nagasawa, Karin Rainey, Hiroaki Okuyama, Jin H. Baek, and Gregg L. Semenza
Cancer Res 2006 66: 2725-2731. [Abstract] [Full Text] [PDF]  

A Novel Mechanism for Integrin-Mediated Ras Activation in Breast Carcinoma Cells: The ₆ß₄ Integrin Regulates ErbB2 Translation and Transactivates Epidermal Growth Factor Receptor/ErbB2 Signaling

Sang-Oh Yoon, Sejeong Shin, and Elizabeth A. Lipscomb
Cancer Res 2006 66: 2732-2739. [Abstract] [Full Text] [PDF]  

Lysophosphatidic Acid Is a Major Regulator of Growth-Regulated Oncogene in Ovarian Cancer

Zendra Lee, Ramona F. Swaby, Yuewei Liang, Shuangxing Yu, Shuying Liu, Karen H. Lu, Robert C. Bast, Jr., Gordon B. Mills, and Xianjun Fang
Cancer Res 2006 66: 2740-2748. [Abstract] [Full Text] [PDF]  

Effects of Transferrin Receptor Blockade on Cancer Cell Proliferation and Hypoxia-Inducible Factor Function and Their Differential Regulation by Ascorbate

Dylan T. Jones, Ian S. Trowbridge, and Adrian L. Harris
Cancer Res 2006 66: 2749-2756. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

The Small Organic Compound HA14-1 Prevents Bcl-2 Interaction with Bax to Sensitize Malignant Glioma Cells to Induction of Cell Death

Florence Manero, Fabien Gautier, Tristan Gallenne, Nicolas Cauquil, Danielle Grée, Pierre-François Cartron, Olivier Geneste, René Grée, François M. Vallette, and Philippe Juin
Cancer Res 2006 66: 2757-2764. [Abstract] [Full Text] [PDF]  

Pharmacogenomic Identification of Novel Determinants of Response to Chemotherapy in Colon Cancer

John Boyer, Wendy L. Allen, Estelle G. McLean, Peter M. Wilson, Andrea McCulla, Stephen Moore, Daniel B. Longley, Carlos Caldas, and Patrick G. Johnston
Cancer Res 2006 66: 2765-2777. [Abstract] [Full Text] [PDF] Supplementary Data  

Down-regulation of Notch-1 Inhibits Invasion by Inactivation of Nuclear Factor-B, Vascular Endothelial Growth Factor, and Matrix Metalloproteinase-9 in Pancreatic Cancer Cells

Zhiwei Wang, Sanjeev Banerjee, Yiwei Li, K.M. Wahidur Rahman, Yuxiang Zhang, and Fazlul H. Sarkar
Cancer Res 2006 66: 2778-2784. [Abstract] [Full Text] [PDF]  

Expression of RASSF1A, an Epigenetically Silenced Tumor Suppressor, Overcomes Resistance to Apoptosis Induction by Interferons

Frederic J. Reu, Douglas W. Leaman, Ratan R. Maitra, Soo In Bae, Leonid Cherkassky, Mark W. Fox, Donald R. Rempinski, Normand Beaulieu, A. Robert MacLeod, and Ernest C. Borden
Cancer Res 2006 66: 2785-2793. [Abstract] [Full Text] [PDF]  

Functional Diversity of DNA Methyltransferase Inhibitors in Human Cancer Cell Lines

Carlo Stresemann, Bodo Brueckner, Tanja Musch, Helga Stopper, and Frank Lyko
Cancer Res 2006 66: 2794-2800. [Abstract] [Full Text] [PDF]  

Novel Nanoliposomal CPT-11 Infused by Convection-Enhanced Delivery in Intracranial Tumors: Pharmacology and Efficacy

Charles O. Noble, Michal T. Krauze, Daryl C. Drummond, Yoji Yamashita, Ryuta Saito, Mitchel S. Berger, Dmitri B. Kirpotin, Krystof S. Bankiewicz, and John W. Park
Cancer Res 2006 66: 2801-2806. [Abstract] [Full Text] [PDF]  

Physicochemical and Pharmacokinetic Characterization of Highly Potent Recombinant L-Methionine -Lyase Conjugated with Polyethylene Glycol as an Antitumor Agent

Tomoaki Takakura, Akio Takimoto, Yoshihide Notsu, Hiroshi Yoshida, Takaomi Ito, Hirofumi Nagatome, Masahiro Ohno, Yoshinao Kobayashi, Takayuki Yoshioka, Kenji Inagaki, Shigeo Yagi, Robert M. Hoffman, and Nobuyoshi Esaki
Cancer Res 2006 66: 2807-2814. [Abstract] [Full Text] [PDF]  

Endocrinology:

Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

Michael Stanbrough, Glenn J. Bubley, Kenneth Ross, Todd R. Golub, Mark A. Rubin, Trevor M. Penning, Phillip G. Febbo, and Steven P. Balk
Cancer Res 2006 66: 2815-2825. [Abstract] [Full Text] [PDF]  

Clinical Research:

The MYCN Enigma: Significance of MYCN Expression in Neuroblastoma

Xao X. Tang, Huaqing Zhao, Bing Kung, David Y. Kim, Sakeenah L. Hicks, Susan L. Cohn, Nai-Kong Cheung, Robert C. Seeger, Audrey E. Evans, and Naohiko Ikegaki
Cancer Res 2006 66: 2826-2833. [Abstract] [Full Text] [PDF] Supplementary Data  

Prognostic Value of an Activation State Marker for Epidermal Growth Factor Receptor in Tissue Microarrays of Head and Neck Cancer

Anthony Kong, Pierre Leboucher, Russell Leek, Véronique Calleja, Stuart Winter, Adrian Harris, Peter J. Parker, and Banafshé Larijani
Cancer Res 2006 66: 2834-2843. [Abstract] [Full Text] [PDF]  

Genetic Polymorphisms in Antioxidant Enzymes Modulate Hepatic Iron Accumulation and Hepatocellular Carcinoma Development in Patients with Alcohol-Induced Cirrhosis

Angela Sutton, Pierre Nahon, Dominique Pessayre, Pierre Rufat, Aurélie Poiré, Marianne Ziol, Dominique Vidaud, Nathalie Barget, Nathalie Ganne-Carrié, Nathalie Charnaux, Jean-Claude Trinchet, Liliane Gattegno, and Michel Beaugrand
Cancer Res 2006 66: 2844-2852. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Chemopreventive Properties of Black Raspberries in N-Nitrosomethylbenzylamine-Induced Rat Esophageal Tumorigenesis: Down-regulation of Cyclooxygenase-2, Inducible Nitric Oxide Synthase, and c-Jun

Tong Chen, Hyejeong Hwang, Miranda E. Rose, Ronald G. Nines, and Gary D. Stoner
Cancer Res 2006 66: 2853-2859. [Abstract] [Full Text] [PDF]  

XRCC1 Genotype and Breast Cancer: Functional Studies and Epidemiologic Data Show Interactions between XRCC1 Codon 280 His and Smoking

Brian F. Pachkowski, Scott Winkel, Yoshiko Kubota, James A. Swenberg, Robert C. Millikan, and Jun Nakamura
Cancer Res 2006 66: 2860-2868. [Abstract] [Full Text] [PDF] Supplementary Data  

A Prospective Study of Hemoglobin A1c Concentrations and Risk of Breast Cancer in Women

Jennifer Lin, Paul M. Ridker, Nader Rifai, I-Min Lee, JoAnn E. Manson, Julie E. Buring, and Shumin M. Zhang
Cancer Res 2006 66: 2869-2875. [Abstract] [Full Text] [PDF]  

Obituary:

Beatrice A. Singer: In Memoriam (1923–2005)

James E. Cleaver, Priscilla K. Cooper, Stuart M. Linn, and Mina J. Bissell
Cancer Res 2006 66: 2876-2877. [Full Text] [PDF]  

Letters to the Editor:

Polymorphisms Associated with Asthma Are Inversely Related to Glioblastoma Multiforme

John Blakely, Judith Schwartzbaum, Maria Feychting, Anders Ahlbom, Beatrice Malmer, Hani Doss, and Waldemar Debinski
Cancer Res 2006 66: 2878-2879. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.