Reviews:

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

Melanie Braig and Clemens A. Schmitt
Cancer Res 2006 66: 2881-2884. doi: 10.1158/0008-5472.CAN-05-4006 [Abstract] [Full Text] [PDF]  

Bcl-2 Inhibition of Autophagy: A New Route to Cancer?

Sophie Pattingre and Beth Levine
Cancer Res 2006 66: 2885-2888. doi: 10.1158/0008-5472.CAN-05-4412 [Abstract] [Full Text] [PDF]  

The Phosphoinositide 3-Kinase/Akt1/Par-4 Axis: A Cancer-Selective Therapeutic Target

Anindya Goswami, Padhma Ranganathan, and Vivek M. Rangnekar
Cancer Res 2006 66: 2889-2892. doi: 10.1158/0008-5472.CAN-05-4458 [Abstract] [Full Text] [PDF]  

Special Lecture:

Reducing the "Risk" of Chemoprevention: Defining and Targeting High Risk—2005 AACR Cancer Research and Prevention Foundation Award Lecture

Scott M. Lippman and J. Jack Lee
Cancer Res 2006 66: 2893-2903. doi: 10.1158/0008-5472.CAN-05-4573 [Abstract] [Full Text] [PDF]  

Meeting Report:

10th Biennial Helene Harris Memorial Trust Meeting

Frances R. Balkwill, Alan Ashworth, Robert C. Bast, Jonathon S. Berek, Jeff Boyd, Mary L. Disis, Hani Gabra, Martin E. Gore, Thomas C. Hamilton, Ian J. Jacobs, Stan B. Kaye, Elise C. Kohn, Gordon B. Mills, and Nicole D. Urban
Cancer Res 2006 66: 2904-2906. doi: 10.1158/0008-5472.CAN-05-2093 [Full Text] [PDF]  

Priority Reports:

Defective p53 Response and Apoptosis Associated with an Ataxia-Telangiectasia–like Phenotype

Nuri Gueven, Olivier J. Becherel, Geoff Birrell, Philip Chen, Giannino DelSal, James P. Carney, Padraic Grattan-Smith, and Martin F. Lavin
Cancer Res 2006 66: 2907-2912. doi: 10.1158/0008-5472.CAN-05-3428 [Abstract] [Full Text] [PDF]  

Signal Transducers and Activators of Transcription 3 Activation Is Involved in Nuclear Accumulation of ß-Catenin in Colorectal Cancer

Mayumi Kawada, Hiroshi Seno, Yoshito Uenoyama, Tateo Sawabu, Naoki Kanda, Hirokazu Fukui, Yasuyuki Shimahara, and Tsutomu Chiba
Cancer Res 2006 66: 2913-2917. doi: 10.1158/0008-5472.CAN-05-3460 [Abstract] [Full Text] [PDF]  

Global Gene Expression Profiling of Circulating Endothelial Cells in Patients with Metastatic Carcinomas

Denis A. Smirnov, Bradley W. Foulk, Gerald V. Doyle, Mark C. Connelly, Leon W.M.M. Terstappen, and S. Mark O'Hara
Cancer Res 2006 66: 2918-2922. doi: 10.1158/0008-5472.CAN-05-4003 [Abstract] [Full Text] [PDF] Supplementary Data  

Prostaglandin E Receptor EP4 Antagonism Inhibits Breast Cancer Metastasis

Xinrong Ma, Namita Kundu, Salah Rifat, Tonya Walser, and Amy M. Fulton
Cancer Res 2006 66: 2923-2927. doi: 10.1158/0008-5472.CAN-05-4348 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Tumor Susceptibility and Apoptosis Defect in a Mouse Strain Expressing a Human p53 Transgene

Crissy Dudgeon, Calvina Kek, Oleg N. Demidov, Shin-ichi Saito, Kenneth Fernandes, Alexandra Diot, Jean-Christophe Bourdon, David P. Lane, Ettore Appella, Albert J. Fornace, Jr., and Dmitry V. Bulavin
Cancer Res 2006 66: 2928-2936. doi: 10.1158/0008-5472.CAN-05-2063 [Abstract] [Full Text] [PDF]  

Hypoxic Culture Induces Expression of Sialin, a Sialic Acid Transporter, and Cancer-Associated Gangliosides Containing Non–Human Sialic Acid on Human Cancer Cells

Jun Yin, Ayako Hashimoto, Mineko Izawa, Keiko Miyazaki, Guo-Yun Chen, Hiromu Takematsu, Yasunori Kozutsumi, Akemi Suzuki, Kimio Furuhata, Feng-Leng Cheng, Chun-Hung Lin, Chihiro Sato, Ken Kitajima, and Reiji Kannagi
Cancer Res 2006 66: 2937-2945. doi: 10.1158/0008-5472.CAN-05-2615 [Abstract] [Full Text] [PDF]  

Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in Cdk4^R24C/R24C/TPras Mice

Elke Hacker, H. Konrad Muller, Nicole Irwin, Brian Gabrielli, Douglas Lincoln, Sandra Pavey, Marianne Broome Powell, Marcos Malumbres, Mariano Barbacid, Nicholas Hayward, and Graeme Walker
Cancer Res 2006 66: 2946-2952. doi: 10.1158/0008-5472.CAN-05-3196 [Abstract] [Full Text] [PDF] Supplementary Data  

Common Cancer Biomarkers

Christopher F. Basil, Yingdong Zhao, Katia Zavaglia, Ping Jin, Monica C. Panelli, Sonia Voiculescu, Susanna Mandruzzato, Hueling M. Lee, Barbara Seliger, Ralph S. Freedman, Phil R. Taylor, Nan Hu, Paola Zanovello, Francesco M. Marincola, and Ena Wang
Cancer Res 2006 66: 2953-2961. doi: 10.1158/0008-5472.CAN-05-3433 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhanced Photocarcinogenesis in Interleukin-12–Deficient Mice

Akira Maeda, Stefan W. Schneider, Motohiro Kojima, Stefan Beissert, Thomas Schwarz, and Agatha Schwarz
Cancer Res 2006 66: 2962-2969. doi: 10.1158/0008-5472.CAN-05-3614 [Abstract] [Full Text] [PDF]  

Global Gene Expression Profiling of Pleural Mesotheliomas: Overexpression of Aurora Kinases and P16/CDKN2A Deletion as Prognostic Factors and Critical Evaluation of Microarray-Based Prognostic Prediction

Fernando López-Ríos, Shannon Chuai, Raja Flores, Shigeki Shimizu, Takatoshi Ohno, Kazuhiko Wakahara, Peter B. Illei, Sanaa Hussain, Lee Krug, Maureen F. Zakowski, Valerie Rusch, Adam B. Olshen, and Marc Ladanyi
Cancer Res 2006 66: 2970-2979. doi: 10.1158/0008-5472.CAN-05-3907 [Abstract] [Full Text] [PDF] Supplementary Data  

HMGA1 Inhibits the Function of p53 Family Members in Thyroid Cancer Cells

Francesco Frasca, Alessandra Rustighi, Roberta Malaguarnera, Sandro Altamura, Paolo Vigneri, Giannino Del Sal, Vincenzo Giancotti, Vincenzo Pezzino, Riccardo Vigneri, and Guidalberto Manfioletti
Cancer Res 2006 66: 2980-2989. doi: 10.1158/0008-5472.CAN-05-2637 [Abstract] [Full Text] [PDF]  

Erythroid Inhibition by the Leukemic Fusion AML1-ETO Is Associated with Impaired Acetylation of the Major Erythroid Transcription Factor GATA-1

Youngjin Choi, Kamaleldin E. Elagib, Lorrie L. Delehanty, and Adam N. Goldfarb
Cancer Res 2006 66: 2990-2996. doi: 10.1158/0008-5472.CAN-05-2944 [Abstract] [Full Text] [PDF]  

Phosphorylation of Nucleotide Excision Repair Factor Xeroderma Pigmentosum Group A by Ataxia Telangiectasia Mutated and Rad3-Related–Dependent Checkpoint Pathway Promotes Cell Survival in Response to UV Irradiation

Xiaoming Wu, Steven M. Shell, Zhengguan Yang, and Yue Zou
Cancer Res 2006 66: 2997-3005. doi: 10.1158/0008-5472.CAN-05-3403 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Lysophosphatidic Acid Is Constitutively Produced by Human Peritoneal Mesothelial Cells and Enhances Adhesion, Migration, and Invasion of Ovarian Cancer Cells

Juan Ren, Yi-jin Xiao, Lisam Shanjukumar Singh, Xiaoxian Zhao, Zhenwen Zhao, Li Feng, Tyler M. Rose, Glenn D. Prestwich, and Yan Xu
Cancer Res 2006 66: 3006-3014. doi: 10.1158/0008-5472.CAN-05-1292 [Abstract] [Full Text] [PDF]  

Elongation Factor-2 Kinase Regulates Autophagy in Human Glioblastoma Cells

Hao Wu, Jin-Ming Yang, Shengkan Jin, Haiyan Zhang, and William N. Hait
Cancer Res 2006 66: 3015-3023. doi: 10.1158/0008-5472.CAN-05-1554 [Abstract] [Full Text] [PDF]  

Nuclear Insulin-Like Growth Factor Binding Protein-3 Induces Apoptosis and Is Targeted to Ubiquitin/Proteasome–Dependent Proteolysis

Frédéric R. Santer, Nicole Bacher, Barbara Moser, Dieter Morandell, Sigrun Ressler, Sue M. Firth, Gilles A. Spoden, Consolato Sergi, Robert C. Baxter, Pidder Jansen-Dürr, and Werner Zwerschke
Cancer Res 2006 66: 3024-3033. doi: 10.1158/0008-5472.CAN-05-2013 [Abstract] [Full Text] [PDF]  

Dynamic Interactions of Cortactin and Membrane Type 1 Matrix Metalloproteinase at Invadopodia: Defining the Stages of Invadopodia Formation and Function

Vira V. Artym, Ying Zhang, Françoise Seillier-Moiseiwitsch, Kenneth M. Yamada, and Susette C. Mueller
Cancer Res 2006 66: 3034-3043. doi: 10.1158/0008-5472.CAN-05-2177 [Abstract] [Full Text] [PDF] Supplementary Data  

Delocalization and Destabilization of the Arf Tumor Suppressor by the Leukemia-Associated NPM Mutant

Emanuela Colombo, Paola Martinelli, Raffaella Zamponi, Danielle C. Shing, Paola Bonetti, Lucilla Luzi, Sara Volorio, Loris Bernard, Giancarlo Pruneri, Myriam Alcalay, and Pier Giuseppe Pelicci
Cancer Res 2006 66: 3044-3050. doi: 10.1158/0008-5472.CAN-05-2378 [Abstract] [Full Text] [PDF]  

Inhibition of Lymphotoxin-ß Receptor–Mediated Cell Death by Survivin-Ex3

Ren-In You, Mei-Chieh Chen, Hsei-Wei Wang, Yang-Chieh Chou, Chi-Hung Lin, and Shie-Liang Hsieh
Cancer Res 2006 66: 3051-3061. doi: 10.1158/0008-5472.CAN-05-2479 [Abstract] [Full Text] [PDF]  

The Secretory Leukocyte Protease Inhibitor Is a Type 1 Insulin-Like Growth Factor Receptor–Regulated Protein that Protects against Liver Metastasis by Attenuating the Host Proinflammatory Response

Ni Wang, Thusanth Thuraisingam, Lucia Fallavollita, Aihao Ding, Danuta Radzioch, and Pnina Brodt
Cancer Res 2006 66: 3062-3070. doi: 10.1158/0008-5472.CAN-05-2638 [Abstract] [Full Text] [PDF]  

A Growth-Related Oncogene/CXC Chemokine Receptor 2 Autocrine Loop Contributes to Cellular Proliferation in Esophageal Cancer

Bo Wang, Denver T. Hendricks, Fred Wamunyokoli, and M. Iqbal Parker
Cancer Res 2006 66: 3071-3077. doi: 10.1158/0008-5472.CAN-05-2871 [Abstract] [Full Text] [PDF]  

Behavioral Profiling of Human Transitional Cell Carcinoma Ex vivo

Carlos R. Estrada, Matthew Salanga, Diane R. Bielenberg, W. Bruce Harrell, David Zurakowski, Xuping Zhu, Matthew R. Palmer, Michael R. Freeman, and Rosalyn M. Adam
Cancer Res 2006 66: 3078-3086. doi: 10.1158/0008-5472.CAN-05-3391 [Abstract] [Full Text] [PDF]  

Inhibition of Interleukin-6 with CNTO328, an Anti-Interleukin-6 Monoclonal Antibody, Inhibits Conversion of Androgen-Dependent Prostate Cancer to an Androgen-Independent Phenotype in Orchiectomized Mice

Lauren Wallner, Jinlu Dai, June Escara-Wilke, Jian Zhang, Zhi Yao, Yi Lu, Mohit Trikha, Jeffrey A. Nemeth, Mohamed H. Zaki, and Evan T. Keller
Cancer Res 2006 66: 3087-3095. doi: 10.1158/0008-5472.CAN-05-3447 [Abstract] [Full Text] [PDF]  

DNA Damage–Induced Protein 14-3-3 Inhibits Protein Kinase B/Akt Activation and Suppresses Akt-Activated Cancer

Huiling Yang, Yu-Ye Wen, Ruiying Zhao, Yu-Li Lin, Keith Fournier, Heng-Yin Yang, Yun Qiu, Jose Diaz, Christine Laronga, and Mong-Hong Lee
Cancer Res 2006 66: 3096-3105. doi: 10.1158/0008-5472.CAN-05-3620 [Abstract] [Full Text] [PDF]  

Increased EP4 Receptor Expression in Colorectal Cancer Progression Promotes Cell Growth and Anchorage Independence

Simon D. Chell, Ian R. Witherden, Richard R. Dobson, Morganaden Moorghen, Andrew A. Herman, David Qualtrough, Ann C. Williams, and Christos Paraskeva
Cancer Res 2006 66: 3106-3113. doi: 10.1158/0008-5472.CAN-05-3702 [Abstract] [Full Text] [PDF]  

Galectin-3 Regulates Mitochondrial Stability and Antiapoptotic Function in Response to Anticancer Drug in Prostate Cancer

Tomoharu Fukumori, Natsuo Oka, Yukinori Takenaka, Pratima Nangia-Makker, Essam Elsamman, Toshinori Kasai, Masayuki Shono, Hiro-omi Kanayama, Julie Ellerhorst, Reuben Lotan, and Avraham Raz
Cancer Res 2006 66: 3114-3119. doi: 10.1158/0008-5472.CAN-05-3750 [Abstract] [Full Text] [PDF]  

Transplantable Tumor Lines Generated in Clonal Zebrafish

Igor V. Mizgireuv and Sergei Y. Revskoy
Cancer Res 2006 66: 3120-3125. doi: 10.1158/0008-5472.CAN-05-3800 [Abstract] [Full Text] [PDF]  

Akt-Mediated Cisplatin Resistance in Ovarian Cancer: Modulation of p53 Action on Caspase-Dependent Mitochondrial Death Pathway

Xiaokui Yang, Michael Fraser, Ute M. Moll, Ajoy Basak, and Benjamin K. Tsang
Cancer Res 2006 66: 3126-3136. doi: 10.1158/0008-5472.CAN-05-0425 [Abstract] [Full Text] [PDF]  

Overexpression of the Oncoprotein Prothymosin Triggers a p53 Response that Involves p53 Acetylation

Takahiko Kobayashi, Ting Wang, Masaji Maezawa, Masanobu Kobayashi, Shunsuke Ohnishi, Kazuteru Hatanaka, Shuhei Hige, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Junji Tanaka, Masahiro Imamura, Kiminori Hasegawa, Yoshiyuki Tanaka, and Rainer K. Brachmann
Cancer Res 2006 66: 3137-3144. doi: 10.1158/0008-5472.CAN-05-2112 [Abstract] [Full Text] [PDF]  

The Oncogenic Epidermal Growth Factor Receptor Variant Xiphophorus Melanoma Receptor Kinase Induces Motility in Melanocytes by Modulation of Focal Adhesions

Svenja Meierjohann, Elisabeth Wende, Anita Kraiss, Claudia Wellbrock, and Manfred Schartl
Cancer Res 2006 66: 3145-3152. doi: 10.1158/0008-5472.CAN-05-2667 [Abstract] [Full Text] [PDF] Supplementary Data  

PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility

James J. Fiordalisi, Patricia J. Keller, and Adrienne D. Cox
Cancer Res 2006 66: 3153-3161. doi: 10.1158/0008-5472.CAN-05-3116 [Abstract] [Full Text] [PDF]  

Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor

James V. Alvarez, Heidi Greulich, William R. Sellers, Matthew Meyerson, and David A. Frank
Cancer Res 2006 66: 3162-3168. doi: 10.1158/0008-5472.CAN-05-3757 [Abstract] [Full Text] [PDF] Supplementary Data  

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

John T. Patton, Lindsey D. Mayo, Aatur D. Singhi, Andrei V. Gudkov, George R. Stark, and Mark W. Jackson
Cancer Res 2006 66: 3169-3176. doi: 10.1158/0008-5472.CAN-05-3832 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Cancer Cell Mitochondria Are Direct Proapoptotic Targets for the Marine Antitumor Drug Lamellarin D

Jérôme Kluza, Miguel-Angel Gallego, Anne Loyens, Jean-Claude Beauvillain, José-Maria Fernandez Sousa-Faro, Carmen Cuevas, Philippe Marchetti, and Christian Bailly
Cancer Res 2006 66: 3177-3187. doi: 10.1158/0008-5472.CAN-05-1929 [Abstract] [Full Text] [PDF]  

Activation of Stat3 in Human Melanoma Promotes Brain Metastasis

Tong-xin Xie, Feng-Ju Huang, Kenneth D. Aldape, Shin-Hyuk Kang, Mingguang Liu, Jeffrey E. Gershenwald, Keping Xie, Raymond Sawaya, and Suyun Huang
Cancer Res 2006 66: 3188-3196. doi: 10.1158/0008-5472.CAN-05-2674 [Abstract] [Full Text] [PDF] Supplementary Data  

Antibody-Drug Conjugates Designed to Eradicate Tumors with Homogeneous and Heterogeneous Expression of the Target Antigen

Yelena V. Kovtun, Charlene A. Audette, Yumei Ye, Hongsheng Xie, Mary F. Ruberti, Sara J. Phinney, Barbara A. Leece, Thomas Chittenden, Walter A. Blättler, and Victor S. Goldmacher
Cancer Res 2006 66: 3214-3221. doi: 10.1158/0008-5472.CAN-05-3973 [Abstract] [Full Text] [PDF]  

Capsaicin, a Component of Red Peppers, Inhibits the Growth of Androgen-Independent, p53 Mutant Prostate Cancer Cells

Akio Mori, Sören Lehmann, James O'Kelly, Takashi Kumagai, Julian C. Desmond, Milena Pervan, William H. McBride, Masahiro Kizaki, and H. Phillip Koeffler
Cancer Res 2006 66: 3222-3229. doi: 10.1158/0008-5472.CAN-05-0087 [Abstract] [Full Text] [PDF]  

A Novel Mechanism of Synergistic Cytotoxicity with 5-Fluorocytosine and Ganciclovir in Double Suicide Gene Therapy

Paul D. Boucher, Michael M. Im, Svend O. Freytag, and Donna S. Shewach
Cancer Res 2006 66: 3230-3237. doi: 10.1158/0008-5472.CAN-05-3033 [Abstract] [Full Text] [PDF]  

4-Oxo-Fenretinide, a Recently Identified Fenretinide Metabolite, Induces Marked G₂-M Cell Cycle Arrest and Apoptosis in Fenretinide-Sensitive and Fenretinide-Resistant Cell Lines

Maria Grazia Villani, Valentina Appierto, Elena Cavadini, Arianna Bettiga, Alessandro Prinetti, Margaret Clagett-Dame, Robert W. Curley, and Franca Formelli
Cancer Res 2006 66: 3238-3247. doi: 10.1158/0008-5472.CAN-05-3362 [Abstract] [Full Text] [PDF]  

Identification of 14-3-3 as a Contributor to Drug Resistance in Human Breast Cancer Cells Using Functional Proteomic Analysis

Yang Liu, Hailan Liu, Baoguang Han, and Jian-Ting Zhang
Cancer Res 2006 66: 3248-3255. doi: 10.1158/0008-5472.CAN-05-3801 [Abstract] [Full Text] [PDF]  

Antiangiogenic Concentrations of Vinflunine Increase the Interphase Microtubule Dynamics and Decrease the Motility of Endothelial Cells

Bertrand Pourroy, Stéphane Honoré, Eddy Pasquier, Véronique Bourgarel-Rey, Anna Kruczynski, Claudette Briand, and Diane Braguer
Cancer Res 2006 66: 3256-3263. doi: 10.1158/0008-5472.CAN-05-3885 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

A Novel Transcriptional Inhibitor Induces Apoptosis in Tumor Cells and Exhibits Antiangiogenic Activity

Senthil K. Radhakrishnan and Andrei L. Gartel
Cancer Res 2006 66: 3264-3270. doi: 10.1158/0008-5472.CAN-05-3940 [Abstract] [Full Text] [PDF] Supplementary Data  

Development of a Highly Active Nanoliposomal Irinotecan Using a Novel Intraliposomal Stabilization Strategy

Daryl C. Drummond, Charles O. Noble, Zexiong Guo, Keelung Hong, John W. Park, and Dmitri B. Kirpotin
Cancer Res 2006 66: 3271-3277. doi: 10.1158/0008-5472.CAN-05-4007 [Abstract] [Full Text] [PDF]  

Experimental Therapuetics, Molecular Targets, and Chemical Biology:

EGFR Tyrosine Kinase Inhibitors Decrease VEGF Expression by Both Hypoxia-Inducible Factor (HIF)-1–Independent and HIF-1–Dependent Mechanisms

Nabendu Pore, Zibin Jiang, Anjali Gupta, George Cerniglia, Gary D. Kao, and Amit Maity
Cancer Res 2006 66: 3197-3204. doi: 10.1158/0008-5472.CAN-05-3090 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental, Therapeutics, Molecular Targets, and Chemical Biology:

Intrapulmonary Administration of CCL21 Gene-Modified Dendritic Cells Reduces Tumor Burden in Spontaneous Murine Bronchoalveolar Cell Carcinoma

Seok-Chul Yang, Raj K. Batra, Sven Hillinger, Karen L. Reckamp, Robert M. Strieter, Steven M. Dubinett, and Sherven Sharma
Cancer Res 2006 66: 3205-3213. doi: 10.1158/0008-5472.CAN-05-3619 [Abstract] [Full Text] [PDF]  

Immunology:

An Inducible Mouse Model of Melanoma Expressing a Defined Tumor Antigen

Ivo J. Huijbers, Paul Krimpenfort, Patrick Chomez, Martin A. van der Valk, Ji-Ying Song, Else-Marit Inderberg-Suso, Anne-Marie Schmitt-Verhulst, Anton Berns, and Benoît J. Van den Eynde
Cancer Res 2006 66: 3278-3286. doi: 10.1158/0008-5472.CAN-05-3216 [Abstract] [Full Text] [PDF] Supplementary Data  

Human Leukocyte Antigen-A2–Restricted CTL Responses to Mutated BRAF Peptides in Melanoma Patients

Rajasekharan Somasundaram, Rolf Swoboda, Laura Caputo, Laszlo Otvos, Barbara Weber, Patricia Volpe, Patricia van Belle, Susan Hotz, David E. Elder, Francesco M. Marincola, Lynn Schuchter, DuPont Guerry, Brian J. Czerniecki, and Dorothee Herlyn
Cancer Res 2006 66: 3287-3293. doi: 10.1158/0008-5472.CAN-05-1932 [Abstract] [Full Text] [PDF]  

Increased Regulatory T-Cell Fraction Amidst a Diminished CD4 Compartment Explains Cellular Immune Defects in Patients with Malignant Glioma

Peter E. Fecci, Duane A. Mitchell, John F. Whitesides, Weihua Xie, Allan H. Friedman, Gary E. Archer, James E. Herndon, II, Darell D. Bigner, Glenn Dranoff, and John H. Sampson
Cancer Res 2006 66: 3294-3302. doi: 10.1158/0008-5472.CAN-05-3773 [Abstract] [Full Text] [PDF]  

Clinical Research:

Vascular Proliferation Is Important for Clinical Progress of Endometrial Cancer

Ingunn M. Stefansson, Helga B. Salvesen, and Lars A. Akslen
Cancer Res 2006 66: 3303-3309. doi: 10.1158/0008-5472.CAN-05-1163 [Abstract] [Full Text] [PDF] Supplementary Data  

Nucleophosmin Mutations in De novo Acute Myeloid Leukemia: The Age-Dependent Incidences and the Stability during Disease Evolution

Wen-Chien Chou, Jih-Luh Tang, Liang-In Lin, Ming Yao, Woei Tsay, Chien-Yuan Chen, Shang-Ju Wu, Chi-Fei Huang, Rong-Jing Chiou, Mei-Hsuan Tseng, Dong-Tsamn Lin, Kai-Hsin Lin, Yao-Chang Chen, and Hwei-Fang Tien
Cancer Res 2006 66: 3310-3316. doi: 10.1158/0008-5472.CAN-05-4316 [Abstract] [Full Text] [PDF] Supplementary Data  

In vivo Margin Assessment during Partial Mastectomy Breast Surgery Using Raman Spectroscopy[?Q1: Running head: Raman Margin Assessment at Partial Mastectomy. Short title OK?Q1]

Abigail S. Haka, Zoya Volynskaya, Joseph A. Gardecki, Jon Nazemi, Joanne Lyons, David Hicks, Maryann Fitzmaurice, Ramachandra R. Dasari, Joseph P. Crowe, and Michael S. Feld
Cancer Res 2006 66: 3317-3322. doi: 10.1158/0008-5472.CAN-05-2815 [Abstract] [Full Text] [PDF]  

Significant Effect of Homologous Recombination DNA Repair Gene Polymorphisms on Pancreatic Cancer Survival

Donghui Li, Hui Liu, Li Jiao, David Z. Chang, Garth Beinart, Robert A. Wolff, Douglas B. Evans, Manal M. Hassan, and James L. Abbruzzese
Cancer Res 2006 66: 3323-3330. doi: 10.1158/0008-5472.CAN-05-3032 [Abstract] [Full Text] [PDF]  

ß T-Cell Receptor Engineered T Cells Mediate Effective Antileukemic Reactivity

Lars T. van der Veken, Renate S. Hagedoorn, Marleen M. van Loenen, Roel Willemze, J.H. Frederik Falkenburg, and Mirjam H.M. Heemskerk
Cancer Res 2006 66: 3331-3337. doi: 10.1158/0008-5472.CAN-05-4190 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Promoter Hypermethylation of Multiple Genes in Sputum Precedes Lung Cancer Incidence in a High-Risk Cohort

Steven A. Belinsky, Kieu C. Liechty, Frederick D. Gentry, Holly J. Wolf, Justin Rogers, Kieu Vu, Jerry Haney, Tim C. Kennedy, Fred R. Hirsch, York Miller, Wilbur A. Franklin, James G. Herman, Stephen B. Baylin, Paul A. Bunn, and Tim Byers
Cancer Res 2006 66: 3338-3344. doi: 10.1158/0008-5472.CAN-05-3408 [Abstract] [Full Text] [PDF]  

Corrections:

Targeting of Genes Involved in MZL

Cancer Res 2006 66: 3345. doi: 10.1158/0008-5472.CAN-66-6-COR1 [Full Text] [PDF]  

TGF-ß Pathway Variants and Breast Cancer Risk

Cancer Res 2006 66: 3345. doi: 10.1158/0008-5472.CAN-66-6-COR2 [Full Text] [PDF]  

Cytoplasmic Retention of RUNX3

Cancer Res 2006 66: 3345. doi: 10.1158/0008-5472.CAN-66-6-COR3 [Full Text] [PDF]  

A Drug Resistance Mechanism of Dormant Tumor Cells

Cancer Res 2006 66: 3345. doi: 10.1158/0008-5472.CAN-66-6-COR4 [Full Text] [PDF]  

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