Award Lecture:

What Remains to Be Done

Nancy G. Brinker
Cancer Res 2007 67: 7939-7940. doi: 10.1158/0008-5472.CAN-07-2650 [Full Text] [PDF]  

Reviews:

Leveraging the Immune System during Chemotherapy: Moving Calreticulin to the Cell Surface Converts Apoptotic Death from "Silent" to Immunogenic

Michel Obeid, Theocharis Panaretakis, Antoine Tesniere, Nick Joza, Roberta Tufi, Lionel Apetoh, François Ghiringhelli, Laurence Zitvogel, and Guido Kroemer
Cancer Res 2007 67: 7941-7944. doi: 10.1158/0008-5472.CAN-07-1622 [Abstract] [Full Text] [PDF]  

Toll-like Receptor Ligands Energize Peptide Vaccines through Multiple Paths

Esteban Celis
Cancer Res 2007 67: 7945-7947. doi: 10.1158/0008-5472.CAN-07-1652 [Abstract] [Full Text] [PDF]  

Priority Reports:

Activation of Double-Stranded RNA–Dependent Protein Kinase, A New Pathway by Which Human Polynucleotide Phosphorylase (hPNPase^old-35) Induces Apoptosis

Devanand Sarkar, Eun Sook Park, Glen N. Barber, and Paul B. Fisher
Cancer Res 2007 67: 7948-7953. doi: 10.1158/0008-5472.CAN-07-0872 [Abstract] [Full Text] [PDF]  

Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung

Yuanbin Chen, Melissa A. De Marco, Irene Graziani, Adi F. Gazdar, Peter R. Strack, Lucio Miele, and Maurizio Bocchetta
Cancer Res 2007 67: 7954-7959. doi: 10.1158/0008-5472.CAN-07-1229 [Abstract] [Full Text] [PDF] Supplementary Data  

A Dual Phosphoinositide-3-Kinase /mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in PTEN-Mutant Glioma

Qi-Wen Fan, Christine K. Cheng, Theodore P. Nicolaides, Christopher S. Hackett, Zachary A. Knight, Kevan M. Shokat, and William A. Weiss
Cancer Res 2007 67: 7960-7965. doi: 10.1158/0008-5472.CAN-07-2154 [Abstract] [Full Text] [PDF] Supplementary Data  

In vivo Role of NAD(P)H:Quinone Oxidoreductase 1 in Metabolic Activation of Mitomycin C and Bone Marrow Cytotoxicity

Anbu Karani Adikesavan, Roberto Barrios, and Anil K. Jaiswal
Cancer Res 2007 67: 7966-7971. doi: 10.1158/0008-5472.CAN-06-4480 [Abstract] [Full Text] [PDF]  

Overexpression of the MicroRNA hsa-miR-200c Leads to Reduced Expression of Transcription Factor 8 and Increased Expression of E-Cadherin

Gregory J. Hurteau, J. Andrew Carlson, Simon D. Spivack, and Graham J. Brock
Cancer Res 2007 67: 7972-7976. doi: 10.1158/0008-5472.CAN-07-1058 [Abstract] [Full Text] [PDF]  

Clostridium perfringens Enterotoxin as a Novel-Targeted Therapeutic for Brain Metastasis

Scott L. Kominsky, Betty Tyler, Jeffrey Sosnowski, Kelly Brady, Michele Doucet, Delissa Nell, James G. Smedley, III, Bruce McClane, Henry Brem, and Saraswati Sukumar
Cancer Res 2007 67: 7977-7982. doi: 10.1158/0008-5472.CAN-07-1314 [Abstract] [Full Text] [PDF]  

Expression of Interleukin-13 Receptor 2 in Glioblastoma Multiforme: Implications for Targeted Therapies

John S. Jarboe, Kory R. Johnson, Yong Choi, Russell R. Lonser, and John K. Park
Cancer Res 2007 67: 7983-7986. doi: 10.1158/0008-5472.CAN-07-1493 [Abstract] [Full Text] [PDF] Supplementary Data  

Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358

Michele Modugno, Elena Casale, Chiara Soncini, Pamela Rosettani, Riccardo Colombo, Rosita Lupi, Luisa Rusconi, Daniele Fancelli, Patrizia Carpinelli, Alexander D. Cameron, Antonella Isacchi, and Jürgen Moll
Cancer Res 2007 67: 7987-7990. doi: 10.1158/0008-5472.CAN-07-1825 [Abstract] [Full Text] [PDF] Supplementary Data  

Heterogeneity of TMPRSS2 Gene Rearrangements in Multifocal Prostate Adenocarcinoma: Molecular Evidence for an Independent Group of Diseases

Rohit Mehra, Bo Han, Scott A. Tomlins, Lei Wang, Anjana Menon, Matthew J. Wasco, Ronglai Shen, James E. Montie, Arul M. Chinnaiyan, and Rajal B. Shah
Cancer Res 2007 67: 7991-7995. doi: 10.1158/0008-5472.CAN-07-2043 [Abstract] [Full Text] [PDF]  

Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7

Jurjen J. Boonstra, Albertina W. van der Velden, Erwin C.W. Beerens, Ronald van Marion, Yuiko Morita-Fujimura, Yasuhisa Matsui, Tetsuro Nishihira, Chris Tselepis, Pierre Hainaut, Anson W. Lowe, Berna H. Beverloo, Herman van Dekken, Hugo W. Tilanus, and Winand N.M. Dinjens
Cancer Res 2007 67: 7996-8001. doi: 10.1158/0008-5472.CAN-07-2064 [Abstract] [Full Text] [PDF]  

Thyroid-Stimulating Hormone–Initiated Proliferative Signals Converge In vivo on the mTOR Kinase without Activating AKT

Charlene Brewer, Nicole Yeager, and Antonio Di Cristofano
Cancer Res 2007 67: 8002-8006. doi: 10.1158/0008-5472.CAN-07-2471 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

HOXA5 Acts Directly Downstream of Retinoic Acid Receptor ß and Contributes to Retinoic Acid–Induced Apoptosis and Growth Inhibition

Hexin Chen, Huiping Zhang, Jishin Lee, Xiaohui Liang, Xinyan Wu, Tao Zhu, Pang-kuo Lo, Xiaokun Zhang, and Saraswati Sukumar
Cancer Res 2007 67: 8007-8013. doi: 10.1158/0008-5472.CAN-07-1405 [Abstract] [Full Text] [PDF]  

YM155, a Novel Small-Molecule Survivin Suppressant, Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts

Takahito Nakahara, Masahiro Takeuchi, Isao Kinoyama, Tsuyoshi Minematsu, Kenna Shirasuna, Akira Matsuhisa, Aya Kita, Fumiko Tominaga, Kentaro Yamanaka, Masafumi Kudoh, and Masao Sasamata
Cancer Res 2007 67: 8014-8021. doi: 10.1158/0008-5472.CAN-07-1343 [Abstract] [Full Text] [PDF]  

Expression of a CALM-AF10 Fusion Gene Leads to Hoxa Cluster Overexpression and Acute Leukemia in Transgenic Mice

David Caudell, Zhenhua Zhang, Yang Jo Chung, and Peter D. Aplan
Cancer Res 2007 67: 8022-8031. doi: 10.1158/0008-5472.CAN-06-3749 [Abstract] [Full Text] [PDF] Supplementary Data  

Genetic Screening Reveals an Essential Role of p27kip1 in Restriction of Breast Cancer Progression

Yuhui Yuan, Li Qin, Dan Liu, Ray-Chang Wu, Paola Mussi, Suoling Zhou, Zhou Songyang, and Jianming Xu
Cancer Res 2007 67: 8032-8042. doi: 10.1158/0008-5472.CAN-07-0083 [Abstract] [Full Text] [PDF] Supplementary Data  

Glutathione Peroxidase 3, Deleted or Methylated in Prostate Cancer, Suppresses Prostate Cancer Growth and Metastasis

Yan P. Yu, Guoying Yu, George Tseng, Kathleen Cieply, Joel Nelson, Marie Defrances, Reza Zarnegar, George Michalopoulos, and Jian-Hua Luo
Cancer Res 2007 67: 8043-8050. doi: 10.1158/0008-5472.CAN-07-0648 [Abstract] [Full Text] [PDF] Supplementary Data  

-Secretase Inhibitor Prevents Notch3 Activation and Reduces Proliferation in Human Lung Cancers

Jun Konishi, Keiko S. Kawaguchi, Huan Vo, Nobuhiro Haruki, Adriana Gonzalez, David P. Carbone, and Thao P. Dang
Cancer Res 2007 67: 8051-8057. doi: 10.1158/0008-5472.CAN-07-1022 [Abstract] [Full Text] [PDF]  

NAC-1 Controls Cell Growth and Survival by Repressing Transcription of Gadd45GIP1, a Candidate Tumor Suppressor

Kentaro Nakayama, Naomi Nakayama, Tian-Li Wang, and Ie-Ming Shih
Cancer Res 2007 67: 8058-8064. doi: 10.1158/0008-5472.CAN-07-1357 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of an Integrated SV40 T/t-Antigen Cancer Signature in Aggressive Human Breast, Prostate, and Lung Carcinomas with Poor Prognosis

Kristin K. Deeb, Aleksandra M. Michalowska, Cheol-yong Yoon, Scott M. Krummey, Mark J. Hoenerhoff, Claudine Kavanaugh, Ming-chung Li, Francesco J. Demayo, Ilona Linnoila, Chu-xia Deng, Eva Y-H.P. Lee, Daniel Medina, Joanna H. Shih, and Jeffrey E. Green
Cancer Res 2007 67: 8065-8080. doi: 10.1158/0008-5472.CAN-07-1515 [Abstract] [Full Text] [PDF] Supplementary Data  

Chromosomal Instability and Supernumerary Centrosomes Represent Precursor Defects in a Mouse Model of T-Cell Lymphoma

Christopher I. van de Wetering and C. Michael Knudson
Cancer Res 2007 67: 8081-8088. doi: 10.1158/0008-5472.CAN-07-1666 [Abstract] [Full Text] [PDF]  

Requirement for Rac1 in a K-ras–Induced Lung Cancer in the Mouse

Joseph L. Kissil, Marita J. Walmsley, Linda Hanlon, Kevin M. Haigis, Carla F. Bender Kim, Alejandro Sweet-Cordero, Matthew S. Eckman, David A. Tuveson, Anthony J. Capobianco, Victor L.J. Tybulewicz, and Tyler Jacks
Cancer Res 2007 67: 8089-8094. doi: 10.1158/0008-5472.CAN-07-2300 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Activation of Insulin-like Growth Factor Signaling Induces Apoptotic Cell Death Under Prolonged Hypoxia by Enhancing Endoplasmic Reticulum Stress Response

Hiroko Endo, Kohei Murata, Mutsuko Mukai, Osamu Ishikawa, and Masahiro Inoue
Cancer Res 2007 67: 8095-8103. doi: 10.1158/0008-5472.CAN-06-3389 [Abstract] [Full Text] [PDF] Supplementary Data  

Ribosomal S6 Kinase 2 Is a Key Regulator in Tumor Promoter–Induced Cell Transformation

Yong-Yeon Cho, Ke Yao, Hong-Gyum Kim, Bong Seok Kang, Duo Zheng, Ann M. Bode, and Zigang Dong
Cancer Res 2007 67: 8104-8112. doi: 10.1158/0008-5472.CAN-06-4668 [Abstract] [Full Text] [PDF] Supplementary Data  

Human Thyroid Tumor Cell Lines Derived from Different Tumor Types Present a Common Dedifferentiated Phenotype

Wilma C.G. van Staveren, David Weiss Solís, Laurent Delys, Laurence Duprez, Guy Andry, Brigitte Franc, Gerry Thomas, Frédérick Libert, Jacques E. Dumont, Vincent Detours, and Carine Maenhaut
Cancer Res 2007 67: 8113-8120. doi: 10.1158/0008-5472.CAN-06-4026 [Abstract] [Full Text] [PDF] Supplementary Data  

Inactivation of Smad4 Accelerates Kras^G12D-Mediated Pancreatic Neoplasia

Kyoko Kojima, Selwyn M. Vickers, N. Volkan Adsay, Nirag C. Jhala, Hyung-Gyoon Kim, Trenton R. Schoeb, William E. Grizzle, and Christopher A. Klug
Cancer Res 2007 67: 8121-8130. doi: 10.1158/0008-5472.CAN-06-4167 [Abstract] [Full Text] [PDF] Supplementary Data  

Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have In vivo Repopulating Activity

Mai-Jing Liao, Cheng Cheng Zhang, Beiyan Zhou, Drazen B. Zimonjic, Sendurai A. Mani, Megan Kaba, Ann Gifford, Ferenc Reinhardt, Nicholas C. Popescu, Wenjun Guo, Elinor Ng Eaton, Harvey F. Lodish, and Robert A. Weinberg
Cancer Res 2007 67: 8131-8138. doi: 10.1158/0008-5472.CAN-06-4493 [Abstract] [Full Text] [PDF] Supplementary Data  

Lipid Raft–Specific Knockdown of Src Family Kinase Activity Inhibits Cell Adhesion and Cell Cycle Progression of Breast Cancer Cells

Taro Hitosugi, Moritoshi Sato, Kazuki Sasaki, and Yoshio Umezawa
Cancer Res 2007 67: 8139-8148. doi: 10.1158/0008-5472.CAN-06-4539 [Abstract] [Full Text] [PDF] Supplementary Data  

Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice

Sylvia A. Bleuming, Xi C. He, Liudmila L. Kodach, James C. Hardwick, Frieda A. Koopman, Fiebo J. ten Kate, Sander J.H. van Deventer, Daniel W. Hommes, Maikel P. Peppelenbosch, G. Johan Offerhaus, Linheng Li, and Gijs R. van den Brink
Cancer Res 2007 67: 8149-8155. doi: 10.1158/0008-5472.CAN-06-4659 [Abstract] [Full Text] [PDF]  

Dendrimer-Modified Magnetic Nanoparticles Enhance Efficiency of Gene Delivery System

Bifeng Pan, Daxiang Cui, Yuan Sheng, Cengiz Ozkan, Feng Gao, Rong He, Qing Li, Ping Xu, and Tuo Huang
Cancer Res 2007 67: 8156-8163. doi: 10.1158/0008-5472.CAN-06-4762 [Abstract] [Full Text] [PDF]  

Identifying the Estrogen Receptor Coactivator PELP1 in Autophagosomes

Kazufumi Ohshiro, Suresh K. Rayala, Seiji Kondo, Amitabh Gaur, Ratna K. Vadlamudi, Adel K. El-Naggar, and Rakesh Kumar
Cancer Res 2007 67: 8164-8171. doi: 10.1158/0008-5472.CAN-07-0038 [Abstract] [Full Text] [PDF]  

Increased Expression of the E3 Ubiquitin Ligase RNF5 Is Associated with Decreased Survival in Breast Cancer

Kenneth D. Bromberg, Harriet M. Kluger, Agnes Delaunay, Sabiha Abbas, Kyle A. DiVito, Stan Krajewski, and Ze'ev Ronai
Cancer Res 2007 67: 8172-8179. doi: 10.1158/0008-5472.CAN-07-0045 [Abstract] [Full Text] [PDF] Supplementary Data  

Chemical Inhibition of Acetyl-CoA Carboxylase Induces Growth Arrest and Cytotoxicity Selectively in Cancer Cells

Annelies Beckers, Sophie Organe, Leen Timmermans, Katryn Scheys, Annelies Peeters, Koen Brusselmans, Guido Verhoeven, and Johannes V. Swinnen
Cancer Res 2007 67: 8180-8187. doi: 10.1158/0008-5472.CAN-07-0389 [Abstract] [Full Text] [PDF]  

Tissue-Specific Consequences of Cyclin D1 Overexpression in Prostate Cancer Progression

Yue He, Omar E. Franco, Ming Jiang, Karin Williams, Harold D. Love, Ilsa M. Coleman, Peter S. Nelson, and Simon W. Hayward
Cancer Res 2007 67: 8188-8197. doi: 10.1158/0008-5472.CAN-07-0418 [Abstract] [Full Text] [PDF] Supplementary Data  

Kallikrein 6 Induces E-Cadherin Shedding and Promotes Cell Proliferation, Migration, and Invasion

Britta Klucky, Regina Mueller, Ingeborg Vogt, Sibylle Teurich, Bettina Hartenstein, Kai Breuhahn, Christa Flechtenmacher, Peter Angel, and Jochen Hess
Cancer Res 2007 67: 8198-8206. doi: 10.1158/0008-5472.CAN-07-0607 [Abstract] [Full Text] [PDF] Supplementary Data  

Cutaneous Human Papillomaviruses Down-regulate AKT1, whereas AKT2 Up-regulation and Activation Associates with Tumors

Ryan F.L. O'Shaughnessy, Baki Akgul, Alan Storey, Herbert Pfister, Catherine A. Harwood, and Carolyn Byrne
Cancer Res 2007 67: 8207-8215. doi: 10.1158/0008-5472.CAN-07-0755 [Abstract] [Full Text] [PDF] Supplementary Data  

Side Population Cells Isolated from Mesenchymal Neoplasms Have Tumor Initiating Potential

Colleen Wu, Qingxia Wei, Velani Utomo, Puviindran Nadesan, Heather Whetstone, Rita Kandel, Jay S. Wunder, and Benjamin A. Alman
Cancer Res 2007 67: 8216-8222. doi: 10.1158/0008-5472.CAN-07-0999 [Abstract] [Full Text] [PDF]  

Real-time Imaging of Tumor-Cell Shedding and Trafficking in Lymphatic Channels

Katsuhiro Hayashi, Ping Jiang, Kensuke Yamauchi, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, A.R. Moossa, Michael Bouvet, and Robert M. Hoffman
Cancer Res 2007 67: 8223-8228. doi: 10.1158/0008-5472.CAN-07-1237 [Abstract] [Full Text] [PDF] Supplementary Data  

Integrative Analysis of Genomic Aberrations Associated with Prostate Cancer Progression

Jung H. Kim, Saravana M. Dhanasekaran, Rohit Mehra, Scott A. Tomlins, Wenjuan Gu, Jianjun Yu, Chandan Kumar-Sinha, Xuhong Cao, Atreya Dash, Lei Wang, Debashis Ghosh, Kerby Shedden, James E. Montie, Mark A. Rubin, Kenneth J. Pienta, Rajal B. Shah, and Arul M. Chinnaiyan
Cancer Res 2007 67: 8229-8239. doi: 10.1158/0008-5472.CAN-07-1297 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Epidermal Growth Factor Receptor (EGFR) Ubiquitination as a Mechanism of Acquired Resistance Escaping Treatment by the Anti-EGFR Monoclonal Antibody Cetuximab

Yang Lu, Xinqun Li, Ke Liang, Rodney Luwor, Zahid H. Siddik, Gordon B. Mills, John Mendelsohn, and Zhen Fan
Cancer Res 2007 67: 8240-8247. doi: 10.1158/0008-5472.CAN-07-0589 [Abstract] [Full Text] [PDF]  

5-Azacytidine–Induced Methyltransferase-DNA Adducts Block DNA Replication In vivo

H. Kenny Kuo, Jack D. Griffith, and Kenneth N. Kreuzer
Cancer Res 2007 67: 8248-8254. doi: 10.1158/0008-5472.CAN-07-1038 [Abstract] [Full Text] [PDF] Supplementary Data  

ICOVIR-5 Shows E2F1 Addiction and Potent Antiglioma Effect In vivo

Marta M. Alonso, Manel Cascallo, Candelaria Gomez-Manzano, Hong Jiang, B. Nebiyou Bekele, Anna Perez-Gimenez, Frederick F. Lang, Yuji Piao, Ramon Alemany, and Juan Fueyo
Cancer Res 2007 67: 8255-8263. doi: 10.1158/0008-5472.CAN-06-4675 [Abstract] [Full Text] [PDF]  

Retinoblastoma Deficiency Increases Chemosensitivity in Lung Cancer

William A. Zagorski, Erik S. Knudsen, and Michael F. Reed
Cancer Res 2007 67: 8264-8273. doi: 10.1158/0008-5472.CAN-06-4753 [Abstract] [Full Text] [PDF]  

Silibinin Sensitizes Human Glioma Cells to TRAIL-Mediated Apoptosis via DR5 Up-regulation and Down-regulation of c-FLIP and Survivin

Yong-gyu Son, Eun Hee Kim, Jin Yeop Kim, Seung U. Kim, Taeg Kyu Kwon, A-Rum Yoon, Chae-Ok Yun, and Kyeong Sook Choi
Cancer Res 2007 67: 8274-8284. doi: 10.1158/0008-5472.CAN-07-0407 [Abstract] [Full Text] [PDF] Supplementary Data  

Use of Reverse Genetics to Enhance the Oncolytic Properties of Newcastle Disease Virus

Adam Vigil, Man-Seong Park, Osvaldo Martinez, Mark A. Chua, Sa Xiao, Jerome F. Cros, Luis Martínez-Sobrido, Savio L.C. Woo, and Adolfo García-Sastre
Cancer Res 2007 67: 8285-8292. doi: 10.1158/0008-5472.CAN-07-1025 [Abstract] [Full Text] [PDF]  

Down-regulation of Forkhead Box M1 Transcription Factor Leads to the Inhibition of Invasion and Angiogenesis of Pancreatic Cancer Cells

Zhiwei Wang, Sanjeev Banerjee, Dejuan Kong, Yiwei Li, and Fazlul H. Sarkar
Cancer Res 2007 67: 8293-8300. doi: 10.1158/0008-5472.CAN-07-1265 [Abstract] [Full Text] [PDF]  

Systemic Delivery of ₁34.5-Deleted Herpes Simplex Virus-1 Selectively Targets and Treats Distant Human Xenograft Tumors That Express High MEK Activity

Jula Veerapong, Kai A. Bickenbach, Michael Y. Shao, Kerrington D. Smith, Mitchell C. Posner, Bernard Roizman, and Ralph R. Weichselbaum
Cancer Res 2007 67: 8301-8306. doi: 10.1158/0008-5472.CAN-07-1499 [Abstract] [Full Text] [PDF]  

A Chemical Screen Identifies Anisomycin as an Anoikis Sensitizer That Functions by Decreasing FLIP Protein Synthesis

Imtiaz A. Mawji, Craig D. Simpson, Marcela Gronda, Moyo A. Williams, Rose Hurren, Clare J. Henderson, Alessandro Datti, Jeffrey L. Wrana, and Aaron D. Schimmer
Cancer Res 2007 67: 8307-8315. doi: 10.1158/0008-5472.CAN-07-1687 [Abstract] [Full Text] [PDF]  

Radiosensitization and Modulation of p44/42 Mitogen-Activated Protein Kinase by 2-Methoxyestradiol in Prostate Cancer Models

Eli V. Casarez, Marya E. Dunlap-Brown, Mark R. Conaway, and George P. Amorino
Cancer Res 2007 67: 8316-8324. doi: 10.1158/0008-5472.CAN-07-1755 [Abstract] [Full Text] [PDF]  

Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases

Karima Bettayeb, Oscar M. Tirado, Séverine Marionneau-Lambot, Yoan Ferandin, Olivier Lozach, Jonathan C. Morris, Silvia Mateo-Lozano, Peter Drueckes, Christoph Schächtele, Michael H.G. Kubbutat, François Liger, Bernard Marquet, Benoît Joseph, Aude Echalier, Jane A. Endicott, Vicente Notario, and Laurent Meijer
Cancer Res 2007 67: 8325-8334. doi: 10.1158/0008-5472.CAN-07-1826 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Gene-Engineered Varicella-Zoster Virus–Reactive CD4⁺ Cytotoxic T Cells Exert Tumor-Specific Effector Function

Silke Landmeier, Bianca Altvater, Sibylle Pscherer, Bodo R. Eing, Joachim Kuehn, Cliona M. Rooney, Heribert Juergens, and Claudia Rossig
Cancer Res 2007 67: 8335-8343. doi: 10.1158/0008-5472.CAN-06-4426 [Abstract] [Full Text] [PDF]  

Foxp3 Expression in Pancreatic Carcinoma Cells as a Novel Mechanism of Immune Evasion in Cancer

Sebastian Hinz, Laia Pagerols-Raluy, Hans-Heinrich Oberg, Ole Ammerpohl, Sandra Grüssel, Bence Sipos, Robert Grützmann, Christian Pilarsky, Hendrik Ungefroren, Hans-Detlev Saeger, Günter Klöppel, Dieter Kabelitz, and Holger Kalthoff
Cancer Res 2007 67: 8344-8350. doi: 10.1158/0008-5472.CAN-06-3304 [Abstract] [Full Text] [PDF]  

Antitumor Effect of Antibody against a SEREX-Defined Antigen (UOEH-LC-1) on Lung Cancer Xenotransplanted into Severe Combined Immunodeficiency Mice

Makiko Mizukami, Takeshi Hanagiri, Manabu Yasuda, Koji Kuroda, Yoshiki Shigematsu, Tetsuro Baba, Takashi Fukuyama, Yoshika Nagata, Tetsuya So, Yoshinobu Ichiki, Masakazu Sugaya, Tomoko So, Mitsuhiro Takenoyama, Kenji Sugio, and Kosei Yasumoto
Cancer Res 2007 67: 8351-8357. doi: 10.1158/0008-5472.CAN-06-3889 [Abstract] [Full Text] [PDF]  

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

Chiara Napoletano, Aurelia Rughetti, Mads P. Agervig Tarp, Julia Coleman, Eric P. Bennett, Gianfranco Picco, Patrizio Sale, Kaori Denda-Nagai, Tatsuro Irimura, Ulla Mandel, Henrik Clausen, Luigi Frati, Joyce Taylor-Papadimitriou, Joy Burchell, and Marianna Nuti
Cancer Res 2007 67: 8358-8367. doi: 10.1158/0008-5472.CAN-07-1035 [Abstract] [Full Text] [PDF]  

Endocrinology:

Insulin-Like Growth Factor-I, Regulating Aromatase Expression through Steroidogenic Factor 1, Supports Estrogen-Dependent Tumor Leydig Cell Proliferation

Rosa Sirianni, Adele Chimento, Rocco Malivindi, Ignazio Mazzitelli, Sebastiano Andò, and Vincenzo Pezzi
Cancer Res 2007 67: 8368-8377. doi: 10.1158/0008-5472.CAN-06-4064 [Abstract] [Full Text] [PDF] Supplementary Data  

Taxol Increases the Amount and T Cell–Activating Ability of Self-Immune Stimulatory Multimolecular Complexes Found in Ovarian Cancer Cells

Naotake Tsuda, David Z. Chang, Takashi Mine, Clay Efferson, Adolfo García-Sastre, Xinhui Wang, Soldano Ferrone, and Constantin G. Ioannides
Cancer Res 2007 67: 8378-8387. doi: 10.1158/0008-5472.CAN-07-0327 [Abstract] [Full Text] [PDF] Supplementary Data  

Activity of Androgen Receptor Antagonist Bicalutamide in Prostate Cancer Cells Is Independent of NCoR and SMRT Corepressors

Myles C. Hodgson, Inna Astapova, Anthony N. Hollenberg, and Steven P. Balk
Cancer Res 2007 67: 8388-8395. doi: 10.1158/0008-5472.CAN-07-0617 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Inhibition of Prostate Cancer Growth by Muscadine Grape Skin Extract and Resveratrol through Distinct Mechanisms

Tamaro S. Hudson, Diane K. Hartle, Stephen D. Hursting, Nomeli P. Nunez, Thomas T.Y. Wang, Heather A. Young, Praveen Arany, and Jeffrey E. Green
Cancer Res 2007 67: 8396-8405. doi: 10.1158/0008-5472.CAN-06-4069 [Abstract] [Full Text] [PDF]  

Seizure 6-Like (SEZ6L) Gene and Risk for Lung Cancer

Ivan P. Gorlov, Peter Meyer, Triantafillos Liloglou, Jonathan Myles, Melanie Barbara Boettger, Adrian Cassidy, Luc Girard, John D. Minna, Reiner Fischer, Stephen Duffy, Margaret R. Spitz, Karl Haeussinger, Stefan Kammerer, Charles Cantor, Rainer Dierkesmann, John K. Field, and Christopher I. Amos
Cancer Res 2007 67: 8406-8411. doi: 10.1158/0008-5472.CAN-06-4784 [Abstract] [Full Text] [PDF] Supplementary Data  

Strong Evidence of a Genetic Determinant for Mammographic Density, a Major Risk Factor for Breast Cancer

Celine M. Vachon, Thomas A. Sellers, Erin E. Carlson, Julie M. Cunningham, Christopher A. Hilker, Regenia L. Smalley, Daniel J. Schaid, Linda E. Kelemen, Fergus J. Couch, and V. Shane Pankratz
Cancer Res 2007 67: 8412-8418. doi: 10.1158/0008-5472.CAN-07-1076 [Abstract] [Full Text] [PDF] Supplementary Data Article Podcast from CR Magazine  

Letters to the Editor:

Comment on: A Validated Mathematical Model of Cell-Mediated Immune Response to Tumor Growth

Sven Gowal, Matteo de Giacomi, and Jean-Yves Le Boudec
Cancer Res 2007 67: 8419-8421. doi: 10.1158/0008-5472.CAN-07-0238 [Full Text] [PDF]  

Comment on: A Validated Mathematical Model of Cell-Mediated Immune Response to Tumor Growth

Lisette G. de Pillis, Ami E. Radunskaya, and Charles L. Wiseman
Cancer Res 2007 67: 8420 [Full Text] [PDF]  

Corrections:

Correction: Oncolytic and Gene Therapy Using HYPR-Ad-IL4

Cancer Res 2007 67: 8422-8423. doi: 10.1158/0008-5472.CAN-67-17-COR1 [Full Text] [PDF]  

Correction: SIRT1 and Prostate Cancer

Cancer Res 2007 67: 8423 [Full Text] [PDF]  

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