REVIEWS:

The Obesity-Cancer Link: Lessons Learned from a Fatless Mouse

Stephen D. Hursting, Nomeli P. Nunez, Lyuba Varticovski, and Charles Vinson
Cancer Res 2007 67: 2391-2393. doi: 10.1158/0008-5472.CAN-06-4237 [Abstract] [Full Text] [PDF]  

Meeting Report:

A Tribute to George F. Vande Woude, a Man of Character: 2006 Scientific Symposium Winning the War against Cancer: From Genomics to Bedside and Back

Bin T. Teh and Nicholas S. Duesbery
Cancer Res 2007 67: 2394-2395. Published Online First March 8, 2007. doi: 10.1158/0008-5472.CAN-06-4304 [Full Text] [PDF]  

Priority Reports:

Mutant p53 Enhances Nuclear Factor B Activation by Tumor Necrosis Factor in Cancer Cells

Lilach Weisz, Alexander Damalas, Michalis Liontos, Panagiotis Karakaidos, Giulia Fontemaggi, Revital Maor-Aloni, Marina Kalis, Massimo Levrero, Sabrina Strano, Vassilis G. Gorgoulis, Varda Rotter, Giovanni Blandino, and Moshe Oren
Cancer Res 2007 67: 2396-2401. doi: 10.1158/0008-5472.CAN-06-2425 [Abstract] [Full Text] [PDF] Supplementary Data  

Purging of the Neuroblastoma Stem Cell Compartment and Tumor Regression on Exposure to Hypoxia or Cytotoxic Treatment

Ilaria Marzi, Massimo D'Amico, Tiziana Biagiotti, Serena Giunti, Maria Vittoria Carbone, David Fredducci, Enzo Wanke, and Massimo Olivotto
Cancer Res 2007 67: 2402-2407. doi: 10.1158/0008-5472.CAN-06-3208 [Abstract] [Full Text] [PDF]  

RAD001 (Everolimus) Delays Tumor Onset and Progression in a Transgenic Mouse Model of Ovarian Cancer

Seiji Mabuchi, Deborah A. Altomare, Denise C. Connolly, Andres Klein-Szanto, Samuel Litwin, Matthew K. Hoelzle, Harvey H. Hensley, Thomas C. Hamilton, and Joseph R. Testa
Cancer Res 2007 67: 2408-2413. doi: 10.1158/0008-5472.CAN-06-4490 [Abstract] [Full Text] [PDF] Supplementary Data  

The Synthetic Triterpenoids CDDO-Methyl Ester and CDDO-Ethyl Amide Prevent Lung Cancer Induced by Vinyl Carbamate in A/J Mice

Karen Liby, Darlene B. Royce, Charlotte R. Williams, Renee Risingsong, Mark M. Yore, Tadashi Honda, Gordon W. Gribble, Ethan Dmitrovsky, Thomas A. Sporn, and Michael B. Sporn
Cancer Res 2007 67: 2414-2419. doi: 10.1158/0008-5472.CAN-06-4534 [Abstract] [Full Text] [PDF]  

Protein-Tyrosine Phosphatase 1B Is Required for HER2/Neu–Induced Breast Cancer

Mohamed Bentires-Alj and Benjamin G. Neel
Cancer Res 2007 67: 2420-2424. Published Online First March 8, 2007. doi: 10.1158/0008-5472.CAN-06-4610 [Abstract] [Full Text] [PDF]  

Extrathymic Generation of Tumor-Specific T Cells from Genetically Engineered Human Hematopoietic Stem Cells via Notch Signaling

Yangbing Zhao, Maria R. Parkhurst, Zhili Zheng, Cyrille J. Cohen, John P. Riley, Luca Gattinoni, Nicholas P. Restifo, Steven A. Rosenberg, and Richard A. Morgan
Cancer Res 2007 67: 2425-2429. doi: 10.1158/0008-5472.CAN-06-3977 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Dominant-Negative Activator Protein 1 (TAM67) Targets Cyclooxygenase-2 and Osteopontin under Conditions in which It Specifically Inhibits Tumorigenesis

Connie P. Matthews, Alysia M. Birkholz, Alyson R. Baker, Christine M. Perella, George R. Beck, Jr., Matthew R. Young, and Nancy H. Colburn
Cancer Res 2007 67: 2430-2438. doi: 10.1158/0008-5472.CAN-06-0522 [Abstract] [Full Text] [PDF] Supplementary Data  

Anaplastic, Plasmablastic, and Plasmacytic Plasmacytomas of Mice: Relationships to Human Plasma Cell Neoplasms and Late-Stage Differentiation of Normal B Cells

Chen-Feng Qi, Jeff X. Zhou, Chang Hoon Lee, Zohreh Naghashfar, Shao Xiang, Alexander L. Kovalchuk, Torgny N. Fredrickson, Janet W. Hartley, Derry C. Roopenian, Wendy F. Davidson, Siegfried Janz, and Herbert C. Morse, III
Cancer Res 2007 67: 2439-2447. doi: 10.1158/0008-5472.CAN-06-1561 [Abstract] [Full Text] [PDF] Supplementary Data  

MYCN-Directed Centrosome Amplification Requires MDM2-Mediated Suppression of p53 Activity in Neuroblastoma Cells

Andrew D. Slack, Zaowen Chen, Andrew D. Ludwig, John Hicks, and Jason M. Shohet
Cancer Res 2007 67: 2448-2455. doi: 10.1158/0008-5472.CAN-06-1661 [Abstract] [Full Text] [PDF]  

Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines

Arti Gaur, David A. Jewell, Yu Liang, Dana Ridzon, Jason H. Moore, Caifu Chen, Victor R. Ambros, and Mark A. Israel
Cancer Res 2007 67: 2456-2468. doi: 10.1158/0008-5472.CAN-06-2698 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Tumor-Specific Splice Variant Rac1b by Dishevelled Promotes Canonical Wnt Signaling and Decreased Adhesion of Colorectal Cancer Cells

Susmita Esufali, George S. Charames, Vaijayanti V. Pethe, Pinella Buongiorno, and Bharati Bapat
Cancer Res 2007 67: 2469-2479. doi: 10.1158/0008-5472.CAN-06-2843 [Abstract] [Full Text] [PDF] Supplementary Data  

Destabilized Adhesion in the Gastric Proliferative Zone and c-Src Kinase Activation Mark the Development of Early Diffuse Gastric Cancer

Bostjan Humar, Ryuji Fukuzawa, Vanessa Blair, Anita Dunbier, Helen More, Amanda Charlton, Han Kwang Yang, Woo Ho Kim, Anthony E. Reeve, Iain Martin, and Parry Guilford
Cancer Res 2007 67: 2480-2489. doi: 10.1158/0008-5472.CAN-06-3021 [Abstract] [Full Text] [PDF]  

Inactivation of Apc in the Mouse Prostate Causes Prostate Carcinoma

Katia J. Bruxvoort, Holli M. Charbonneau, Troy A. Giambernardi, James C. Goolsby, Chao-Nan Qian, Cassandra R. Zylstra, Daniel R. Robinson, Pradip Roy-Burman, Aubie K. Shaw, Bree D. Buckner-Berghuis, Robert E. Sigler, James H. Resau, Ruth Sullivan, Wade Bushman, and Bart O. Williams
Cancer Res 2007 67: 2490-2496. doi: 10.1158/0008-5472.CAN-06-3028 [Abstract] [Full Text] [PDF] Supplementary Data  

Concomitant Activation of the JAK/STAT, PI3K/AKT, and ERK Signaling Is Involved in Leptin-Mediated Promotion of Invasion and Migration of Hepatocellular Carcinoma Cells

Neeraj K. Saxena, Dipali Sharma, Xiaokun Ding, Songbai Lin, Fabio Marra, Didier Merlin, and Frank A. Anania
Cancer Res 2007 67: 2497-2507. doi: 10.1158/0008-5472.CAN-06-3075 [Abstract] [Full Text] [PDF]  

Fine Mapping and Candidate Gene Analyses of Pulmonary Adenoma Resistance 1, a Major Genetic Determinant of Mouse Lung Adenoma Resistance

Min Wang, Zhongqiu Zhang, Zhuo Zhang, Haris Vikis, Ying Yan, Yian Wang, and Ming You
Cancer Res 2007 67: 2508-2516. doi: 10.1158/0008-5472.CAN-06-3157 [Abstract] [Full Text] [PDF]  

Dikkopf-1 as a Novel Serologic and Prognostic Biomarker for Lung and Esophageal Carcinomas

Takumi Yamabuki, Atsushi Takano, Satoshi Hayama, Nobuhisa Ishikawa, Tatsuya Kato, Masaki Miyamoto, Tomoo Ito, Hiroyuki Ito, Yohei Miyagi, Haruhiko Nakayama, Masahiro Fujita, Masao Hosokawa, Eiju Tsuchiya, Nobuoki Kohno, Satoshi Kondo, Yusuke Nakamura, and Yataro Daigo
Cancer Res 2007 67: 2517-2525. doi: 10.1158/0008-5472.CAN-06-3369 [Abstract] [Full Text] [PDF]  

Long-term XPC Silencing Reduces DNA Double-Strand Break Repair

Emmanuelle Despras, Petra Pfeiffer, Bernard Salles, Patrick Calsou, Steffi Kuhfittig-Kulle, Jaime F. Angulo, and Denis S.F. Biard
Cancer Res 2007 67: 2526-2534. doi: 10.1158/0008-5472.CAN-06-3371 [Abstract] [Full Text] [PDF]  

Involvement of IFN Regulatory Factor (IRF)-1 and IRF-2 in the Formation and Progression of Human Esophageal Cancers

Yan Wang, Dong-Ping Liu, Ping-Ping Chen, H. Phillip Koeffler, Xiang-Jun Tong, and Dong Xie
Cancer Res 2007 67: 2535-2543. doi: 10.1158/0008-5472.CAN-06-3530 [Abstract] [Full Text] [PDF] Supplementary Data  

Genome-Wide, High-Resolution Detection of Copy Number, Loss of Heterozygosity, and Genotypes from Formalin-Fixed, Paraffin-Embedded Tumor Tissue Using Microarrays

Sharoni Jacobs, Ella R. Thompson, Yasuhito Nannya, Go Yamamoto, Raji Pillai, Seishi Ogawa, Dione K. Bailey, and Ian G. Campbell
Cancer Res 2007 67: 2544-2551. doi: 10.1158/0008-5472.CAN-06-3597 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibitor of Growth 4 Suppresses Cell Spreading and Cell Migration by Interacting with a Novel Binding Partner, Liprin 1

Jiang-Cheng Shen, Motoko Unoki, Damien Ythier, Alain Duperray, Lyuba Varticovski, Kensuke Kumamoto, Remy Pedeux, and Curtis C. Harris
Cancer Res 2007 67: 2552-2558. doi: 10.1158/0008-5472.CAN-06-3870 [Abstract] [Full Text] [PDF] Supplementary Data  

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

Mads Daugaard, Thomas Kirkegaard-Sørensen, Marie Stampe Ostenfeld, Mads Aaboe, Maria Høyer-Hansen, Torben Falck Ørntoft, Mikkel Rohde, and Marja Jäättelä
Cancer Res 2007 67: 2559-2567. doi: 10.1158/0008-5472.CAN-06-4121 [Abstract] [Full Text] [PDF]  

Oncogenic Role of KIAA0101 Interacting with Proliferating Cell Nuclear Antigen in Pancreatic Cancer

Masayo Hosokawa, Akio Takehara, Koichi Matsuda, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Yasuhisa Shinomura, Kohzoh Imai, Yusuke Nakamura, and Hidewaki Nakagawa
Cancer Res 2007 67: 2568-2576. doi: 10.1158/0008-5472.CAN-06-4356 [Abstract] [Full Text] [PDF]  

Epigenetic Regulation of the Human Retinoblastoma Tumor Suppressor Gene Promoter by CTCF

Inti A. De La Rosa-Velázquez, Héctor Rincón-Arano, Luis Benítez-Bribiesca, and Félix Recillas-Targa
Cancer Res 2007 67: 2577-2585. doi: 10.1158/0008-5472.CAN-06-2024 [Abstract] [Full Text] [PDF]  

G-Rich Proto-Oncogenes Are Targeted for Genomic Instability in B-Cell Lymphomas

Michelle L. Duquette, Michael D. Huber, and Nancy Maizels
Cancer Res 2007 67: 2586-2594. doi: 10.1158/0008-5472.CAN-06-2419 [Abstract] [Full Text] [PDF] Supplementary Data  

15-Deoxy-^12,14-Prostaglandin J₂ Inhibits Transcriptional Activity of Estrogen Receptor- via Covalent Modification of DNA-Binding Domain

Han-Jong Kim, Joon-Young Kim, Zhaojing Meng, Li Hua Wang, Fa Liu, Thomas P. Conrads, Terrence R. Burke, Timothy D. Veenstra, and William L. Farrar
Cancer Res 2007 67: 2595-2602. doi: 10.1158/0008-5472.CAN-06-3043 [Abstract] [Full Text] [PDF] Supplementary Data  

p53-Independent Abrogation of a Postmitotic Checkpoint Contributes to Human Papillomavirus E6-Induced Polyploidy

Yingwang Liu, Susan A. Heilman, Diego Illanes, Greenfield Sluder, and Jason J. Chen
Cancer Res 2007 67: 2603-2610. doi: 10.1158/0008-5472.CAN-06-3436 [Abstract] [Full Text] [PDF] Supplementary Data  

Association of CYP1B1 Germ Line Mutations with Hepatocyte Nuclear Factor 1–Mutated Hepatocellular Adenoma

Emmanuelle Jeannot, Karine Poussin, Laurence Chiche, Yannick Bacq, Nathalie Sturm, Jean-Yves Scoazec, Catherine Buffet, Jeanne Tran Van Nhieu, Christine Bellanné-Chantelot, Claudia de Toma, Pierre Laurent-Puig, Paulette Bioulac-Sage, and Jessica Zucman-Rossi
Cancer Res 2007 67: 2611-2616. doi: 10.1158/0008-5472.CAN-06-3947 [Abstract] [Full Text] [PDF] Supplementary Data  

Large-Scale CpG Methylation Analysis Identifies Novel Candidate Genes and Reveals Methylation Hotspots in Acute Lymphoblastic Leukemia

Kristen H. Taylor, Keila E. Pena-Hernandez, J. Wade Davis, Gerald L. Arthur, Deiter J. Duff, Huidong Shi, Farah B. Rahmatpanah, Ozy Sjahputera, and Charles W. Caldwell
Cancer Res 2007 67: 2617-2625. doi: 10.1158/0008-5472.CAN-06-3993 [Abstract] [Full Text] [PDF] Supplementary Data  

The Telomerase Reverse Transcriptase (hTERT) Gene Is a Direct Target of the Histone Methyltransferase SMYD3

Cheng Liu, Xiaolei Fang, Zheng Ge, Marit Jalink, Satoru Kyo, Magnus Björkholm, Astrid Gruber, Jan Sjöberg, and Dawei Xu
Cancer Res 2007 67: 2626-2631. doi: 10.1158/0008-5472.CAN-06-4126 [Abstract] [Full Text] [PDF]  

Genome-Wide Loss of Heterozygosity and Copy Number Analysis in Melanoma Using High-Density Single-Nucleotide Polymorphism Arrays

Mitchell Stark and Nicholas Hayward
Cancer Res 2007 67: 2632-2642. doi: 10.1158/0008-5472.CAN-06-4152 [Abstract] [Full Text] [PDF] Supplementary Data  

Oncogenic Activation of the RAS/RAF Signaling Pathway Impairs the Response of Metastatic Colorectal Cancers to Anti–Epidermal Growth Factor Receptor Antibody Therapies

Silvia Benvenuti, Andrea Sartore-Bianchi, Federica Di Nicolantonio, Carlo Zanon, Mauro Moroni, Silvio Veronese, Salvatore Siena, and Alberto Bardelli
Cancer Res 2007 67: 2643-2648. doi: 10.1158/0008-5472.CAN-06-4158 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors

Jeffrey B. Wyckoff, Yarong Wang, Elaine Y. Lin, Jiu-feng Li, Sumanta Goswami, E. Richard Stanley, Jeffrey E. Segall, Jeffrey W. Pollard, and John Condeelis
Cancer Res 2007 67: 2649-2656. doi: 10.1158/0008-5472.CAN-06-1823 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Cloning of hMena (ENAH) and Its Splice Variant hMena^+11a: Epidermal Growth Factor Increases Their Expression and Stimulates hMena^+11a Phosphorylation in Breast Cancer Cell Lines

Francesca Di Modugno, Lucia DeMonte, Michele Balsamo, Giovanna Bronzi, Maria Rita Nicotra, Massimo Alessio, Elke Jager, John S. Condeelis, Angela Santoni, Pier Giorgio Natali, and Paola Nisticò
Cancer Res 2007 67: 2657-2665. doi: 10.1158/0008-5472.CAN-06-1997 [Abstract] [Full Text] [PDF]  

Adrenomedullin Is Expressed in Pancreatic Cancer and Stimulates Cell Proliferation and Invasion in an Autocrine Manner via the Adrenomedullin Receptor, ADMR

Vijaya Ramachandran, Thiruvengadam Arumugam, Rosa F. Hwang, Joel K. Greenson, Diane M. Simeone, and Craig D. Logsdon
Cancer Res 2007 67: 2666-2675. doi: 10.1158/0008-5472.CAN-06-3362 [Abstract] [Full Text] [PDF]  

Genetic Alterations in Mouse Medulloblastomas and Generation of Tumors De novo from Primary Cerebellar Granule Neuron Precursors

Frederique Zindy, Tamar Uziel, Olivier Ayrault, Christopher Calabrese, Marc Valentine, Jerold E. Rehg, Richard J. Gilbertson, Charles J. Sherr, and Martine F. Roussel
Cancer Res 2007 67: 2676-2684. doi: 10.1158/0008-5472.CAN-06-3418 [Abstract] [Full Text] [PDF] Supplementary Data  

Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate

Ying Liu, Michelle Tseng, Sophie A. Perdreau, Ferdinand Rossi, Cristina Antonescu, Peter Besmer, Jonathan A. Fletcher, Stefan Duensing, and Anette Duensing
Cancer Res 2007 67: 2685-2692. doi: 10.1158/0008-5472.CAN-06-3497 [Abstract] [Full Text] [PDF] Supplementary Data  

Integrin _vß₃ Controls Activity and Oncogenic Potential of Primed c-Src

Stephan Huveneers, Iman van den Bout, Petra Sonneveld, Ana Sancho, Arnoud Sonnenberg, and Erik H.J. Danen
Cancer Res 2007 67: 2693-2700. doi: 10.1158/0008-5472.CAN-06-3654 [Abstract] [Full Text] [PDF] Supplementary Data  

Neuronal Differentiation and Synaptogenesis in Retinoblastoma

Dianna A. Johnson, Jiakun Zhang, Sharon Frase, Matthew Wilson, Carlos Rodriguez-Galindo, and Michael A. Dyer
Cancer Res 2007 67: 2701-2711. doi: 10.1158/0008-5472.CAN-06-3754 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of a Fibroblast Growth Factor Receptor 1 Splice Variant That Inhibits Pancreatic Cancer Cell Growth

Zhanbing Liu, Nicola Neiss, Shaoxia Zhou, Doris Henne-Bruns, Murray Korc, Max Bachem, and Marko Kornmann
Cancer Res 2007 67: 2712-2719. doi: 10.1158/0008-5472.CAN-06-3843 [Abstract] [Full Text] [PDF]  

Warm Hepatic Ischemia-Reperfusion Promotes Growth of Colorectal Carcinoma Micrometastases in Mouse Liver via Matrix Metalloproteinase-9 Induction

Ian B. Nicoud, Christopher M. Jones, Janene M. Pierce, T. Mark Earl, Lynn M. Matrisian, Ravi S. Chari, and D. Lee Gorden
Cancer Res 2007 67: 2720-2728. doi: 10.1158/0008-5472.CAN-06-3923 [Abstract] [Full Text] [PDF]  

Effect of Vascular Normalization by Antiangiogenic Therapy on Interstitial Hypertension, Peritumor Edema, and Lymphatic Metastasis: Insights from a Mathematical Model

Rakesh K. Jain, Ricky T. Tong, and Lance L. Munn
Cancer Res 2007 67: 2729-2735. doi: 10.1158/0008-5472.CAN-06-4102 [Abstract] [Full Text] [PDF] Supplementary Data  

Metallothionein Expression Is Suppressed in Primary Human Hepatocellular Carcinomas and Is Mediated through Inactivation of CCAAT/Enhancer Binding Protein by Phosphatidylinositol 3-Kinase Signaling Cascade

Jharna Datta, Sarmila Majumder, Huban Kutay, Tasneem Motiwala, Wendy Frankel, Robert Costa, Hyuk C. Cha, Ormond A. MacDougald, Samson T. Jacob, and Kalpana Ghoshal
Cancer Res 2007 67: 2736-2746. doi: 10.1158/0008-5472.CAN-06-4433 [Abstract] [Full Text] [PDF] Supplementary Data  

Mullerian-Inhibiting Substance Induces Gro-ß Expression in Breast Cancer Cells through a Nuclear Factor-B–Dependent and Smad1-Dependent Mechanism

Vandana Gupta, Giminna Yeo, Hirofumi Kawakubo, Vivek Rangnekar, Preethi Ramaswamy, Tetsu Hayashida, David T. MacLaughlin, Patricia K. Donahoe, and Shyamala Maheswaran
Cancer Res 2007 67: 2747-2756. doi: 10.1158/0008-5472.CAN-06-2312 [Abstract] [Full Text] [PDF]  

A Single Nucleotide Polymorphism in the MDM2 Gene Disrupts the Oscillation of p53 and MDM2 Levels in Cells

Wenwei Hu, Zhaohui Feng, Lan Ma, John Wagner, J. Jeremy Rice, Gustavo Stolovitzky, and Arnold J. Levine
Cancer Res 2007 67: 2757-2765. doi: 10.1158/0008-5472.CAN-06-2656 [Abstract] [Full Text] [PDF]  

Chemoresistance of Endothelial Cells Induced by Basic Fibroblast Growth Factor Depends on Raf-1–Mediated Inhibition of the Proapoptotic Kinase, ASK1

Alireza S. Alavi, Lisette Acevedo, Wang Min, and David A. Cheresh
Cancer Res 2007 67: 2766-2772. doi: 10.1158/0008-5472.CAN-06-3648 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Radionuclide Therapy of HER2-Positive Microxenografts Using a ¹⁷⁷Lu-Labeled HER2-Specific Affibody Molecule

Vladimir Tolmachev, Anna Orlova, Rikard Pehrson, Joakim Galli, Barbro Baastrup, Karl Andersson, Mattias Sandström, Daniel Rosik, Jörgen Carlsson, Hans Lundqvist, Anders Wennborg, and Fredrik Y. Nilsson
Cancer Res 2007 67: 2773-2782. doi: 10.1158/0008-5472.CAN-06-1630 [Abstract] [Full Text] [PDF]  

The Proteasome Inhibitor Bortezomib Acts Independently of p53 and Induces Cell Death via Apoptosis and Mitotic Catastrophe in B-Cell Lymphoma Cell Lines

Sandra J. Strauss, Karen Higginbottom, Simone Jüliger, Lenushka Maharaj, Paul Allen, David Schenkein, T. Andrew Lister, and Simon P. Joel
Cancer Res 2007 67: 2783-2790. doi: 10.1158/0008-5472.CAN-06-3254 [Abstract] [Full Text] [PDF]  

A Target Cell–Specific Activatable Fluorescence Probe for In vivo Molecular Imaging of Cancer Based on a Self-Quenched Avidin-Rhodamine Conjugate

Yukihiro Hama, Yasuteru Urano, Yoshinori Koyama, Mako Kamiya, Marcelino Bernardo, Ronald S. Paik, In Soo Shin, Chang H. Paik, Peter L. Choyke, and Hisataka Kobayashi
Cancer Res 2007 67: 2791-2799. doi: 10.1158/0008-5472.CAN-06-3315 [Abstract] [Full Text] [PDF]  

Dasatinib Inhibits Migration and Invasion in Diverse Human Sarcoma Cell Lines and Induces Apoptosis in Bone Sarcoma Cells Dependent on Src Kinase for Survival

Audrey C. Shor, Elizabeth A. Keschman, Francis Y. Lee, Carlos Muro-Cacho, G. Douglas Letson, Jonathan C. Trent, W. Jack Pledger, and Richard Jove
Cancer Res 2007 67: 2800-2808. doi: 10.1158/0008-5472.CAN-06-3469 [Abstract] [Full Text] [PDF]  

Angiotensin-(1-7) Inhibits Growth of Human Lung Adenocarcinoma Xenografts in Nude Mice through a Reduction in Cyclooxygenase-2

Jyotsana Menon, David R. Soto-Pantoja, Michael F. Callahan, J. Mark Cline, Carlos M. Ferrario, E. Ann Tallant, and Patricia E. Gallagher
Cancer Res 2007 67: 2809-2815. doi: 10.1158/0008-5472.CAN-06-3614 [Abstract] [Full Text] [PDF]  

Betulinic Acid Inhibits Prostate Cancer Growth through Inhibition of Specificity Protein Transcription Factors

Sudhakar Chintharlapalli, Sabitha Papineni, Shashi K. Ramaiah, and Stephen Safe
Cancer Res 2007 67: 2816-2823. doi: 10.1158/0008-5472.CAN-06-3735 [Abstract] [Full Text] [PDF]  

Galectin-7 in Lymphoma: Elevated Expression in Human Lymphoid Malignancies and Decreased Lymphoma Dissemination by Antisense Strategies in Experimental Model

Mélanie Demers, Katherine Biron-Pain, Josée Hébert, Alain Lamarre, Thierry Magnaldo, and Yves St-Pierre
Cancer Res 2007 67: 2824-2829. doi: 10.1158/0008-5472.CAN-06-3891 [Abstract] [Full Text] [PDF]  

Functional Neoangiogenesis Imaging of Genetically Engineered Mouse Prostate Cancer Using Three-Dimensional Power Doppler Ultrasound

Jim W. Xuan, Michael Bygrave, Hongyi Jiang, Fatma Valiyeva, Joy Dunmore-Buyze, David W. Holdsworth, Jonathan I. Izawa, Glenn Bauman, Madeleine Moussa, Scott F. Winter, Norman M. Greenberg, Joseph L. Chin, Maria Drangova, Aaron Fenster, and James C. Lacefield
Cancer Res 2007 67: 2830-2839. doi: 10.1158/0008-5472.CAN-06-3944 [Abstract] [Full Text] [PDF] Supplementary Data  

Oncolytic Immunovirotherapy for Melanoma Using Vesicular Stomatitis Virus

Rosa Maria Diaz, Feorillo Galivo, Timothy Kottke, Phonphimon Wongthida, Jian Qiao, Jill Thompson, Mikael Valdes, Glen Barber, and Richard G. Vile
Cancer Res 2007 67: 2840-2848. doi: 10.1158/0008-5472.CAN-06-3974 [Abstract] [Full Text] [PDF]  

Caveolin-1–Deficient Mice Have Increased Tumor Microvascular Permeability, Angiogenesis, and Growth

Michelle I. Lin, Jun Yu, Takahisa Murata, and William C. Sessa
Cancer Res 2007 67: 2849-2856. doi: 10.1158/0008-5472.CAN-06-4082 [Abstract] [Full Text] [PDF]  

Oncolytic Treatment and Cure of Neuroblastoma by a Novel Attenuated Poliovirus in a Novel Poliovirus-Susceptible Animal Model

Hidemi Toyoda, Jiang Yin, Steffen Mueller, Eckard Wimmer, and Jeronimo Cello
Cancer Res 2007 67: 2857-2864. doi: 10.1158/0008-5472.CAN-06-3713 [Abstract] [Full Text] [PDF]  

Sensitization of Mesothelioma Cells to Tumor Necrosis Factor–Related Apoptosis–Inducing Ligand–Induced Apoptosis by Heat Stress via the Inhibition of the 3-Phosphoinositide-Dependent Kinase 1/Akt Pathway

Melissa H. Pespeni, Maki Hodnett, Keith S. Abayasiriwardana, Jérémie Roux, Marybeth Howard, V. Courtney Broaddus, and Jean-François Pittet
Cancer Res 2007 67: 2865-2871. doi: 10.1158/0008-5472.CAN-06-3871 [Abstract] [Full Text] [PDF]  

Immunology:

Combining Adoptive Cellular and Immunocytokine Therapies to Improve Treatment of B-Lineage Malignancy

Harjeet Singh, Lisa Marie Serrano, Timothy Pfeiffer, Simon Olivares, George McNamara, David D. Smith, Zaid Al-Kadhimi, Stephen J. Forman, Stephen D. Gillies, Michael C. Jensen, David Colcher, Andrew Raubitschek, and Laurence J.N. Cooper
Cancer Res 2007 67: 2872-2880. doi: 10.1158/0008-5472.CAN-06-2283 [Abstract] [Full Text] [PDF] Supplementary Data  

Therapy of Established Tumors in a Novel Murine Model Transgenic for Human Carcinoembryonic Antigen and HLA-A2 with a Combination of Anti-idiotype Vaccine and CTL Peptides of Carcinoembryonic Antigen

Asim Saha, Sunil K. Chatterjee, Kenneth A. Foon, Esteban Celis, and Malaya Bhattacharya-Chatterjee
Cancer Res 2007 67: 2881-2892. doi: 10.1158/0008-5472.CAN-06-3045 [Abstract] [Full Text] [PDF]  

Clinical Research:

Low-Level TOP2A Amplification in Prostate Cancer Is Associated with HER2 Duplication, Androgen Resistance, and Decreased Survival

Amanda J. Murphy, Caroline A. Hughes, Ciara Barrett, Hilary Magee, Barbara Loftus, John J. O'Leary, and Orla Sheils
Cancer Res 2007 67: 2893-2898. doi: 10.1158/0008-5472.CAN-06-2962 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Picropodophyllotoxin or Podophyllotoxin Does Not Induce Cell Death via Insulin-like Growth Factor-I Receptor

Stig Linder, Maria C. Shoshan, and Radhey S. Gupta
Cancer Res 2007 67: 2899 [Full Text] [PDF]  

Cyclolignans as Inhibitors of the Insulin-like Growth Factor-I Receptor

Olle Larsson and Magnus Axelson
Cancer Res 2007 67: 2899 [Full Text] [PDF]  

5-AZA-2'-Deoxycytidine in Cancer Immunotherapy: A Mouse to Man Story

Sandra Coral, Luca Sigalotti, Alessia Covre, Hugues J.M. Nicolay, Pier Giorgio Natali, and Michele Maio
Cancer Res 2007 67: 2900 [Full Text] [PDF]  

5-AZA-2'-Deoxycytidine in Cancer Immunotherapy: A Mouse to Man Story

Z. Sheng Guo, Nicholas P. Restifo, and David S. Schrump
Cancer Res 2007 67: 2901 [Full Text] [PDF]  

Defining Women at High Risk of Ovarian Cancer

Elizabeth M. Swisher and Mary-Claire King
Cancer Res 2007 67: 2902 [Full Text] [PDF]  

Defining Women at High Risk of Ovarian Cancer

Grover C. Bagby and Tanja Pejovic
Cancer Res 2007 67: 2902-2903. doi: 10.1158/0008-5472.CAN-06-4401 [Full Text] [PDF]  

Correction:

Breast Cancer and Gastrointestinal Bacteria

Cancer Res 2007 67: 2904 [Full Text] [PDF]  

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