Reviews:

Human Leukocyte Antigen–G and Cancer Immunoediting

Mirjana Urosevic and Reinhard Dummer
Cancer Res 2008 68: 627-630. doi: 10.1158/0008-5472.CAN-07-2704 [Abstract] [Full Text] [PDF]  

Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy

Jeremy R. Graff, Bruce W. Konicek, Julia H. Carter, and Eric G. Marcusson
Cancer Res 2008 68: 631-634. doi: 10.1158/0008-5472.CAN-07-5635 [Abstract] [Full Text] [PDF]  

Meeting Report:

Meeting Report: Innovations in Prostate Cancer Research

Wadih Arap, Martin Trepel, Bruce R. Zetter, and Renata Pasqualini
Cancer Res 2008 68: 635-638. Published Online First February 1, 2008. doi: 10.1158/0008-5472.CAN-07-3232 [Full Text] [PDF]  

Priority Reports:

Alterations in Gemin5 Expression Contribute to Alternative mRNA Splicing Patterns and Tumor Cell Motility

Jong Heun Lee, Christine E. Horak, Chand Khanna, Zhaojing Meng, Li Rong Yu, Timothy D. Veenstra, and Patricia S. Steeg
Cancer Res 2008 68: 639-644. doi: 10.1158/0008-5472.CAN-07-2632 [Abstract] [Full Text] [PDF] Supplementary Data  

A First-Generation Multiplex Biomarker Analysis of Urine for the Early Detection of Prostate Cancer

Bharathi Laxman, David S. Morris, Jianjun Yu, Javed Siddiqui, Jie Cao, Rohit Mehra, Robert J. Lonigro, Alex Tsodikov, John T. Wei, Scott A. Tomlins, and Arul M. Chinnaiyan
Cancer Res 2008 68: 645-649. doi: 10.1158/0008-5472.CAN-07-3224 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

Keith S. Hoek, Ossia M. Eichhoff, Natalie C. Schlegel, Udo Döbbeling, Nikita Kobert, Leo Schaerer, Silvio Hemmi, and Reinhard Dummer
Cancer Res 2008 68: 650-656. doi: 10.1158/0008-5472.CAN-07-2491 [Abstract] [Full Text] [PDF] Supplementary Data  

Multiple Alternative Splicing Markers for Ovarian Cancer

Roscoe Klinck, Anne Bramard, Lyna Inkel, Geneviève Dufresne-Martin, Julien Gervais-Bird, Richard Madden, Éric R. Paquet, ChuShin Koh, Julian P. Venables, Panagiotis Prinos, Manuela Jilaveanu-Pelmus, Raymund Wellinger, Claudine Rancourt, Benoit Chabot, and Sherif Abou Elela
Cancer Res 2008 68: 657-663. doi: 10.1158/0008-5472.CAN-07-2580 [Abstract] [Full Text] [PDF] Supplementary Data  

Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma

William M. Lin, Alissa C. Baker, Rameen Beroukhim, Wendy Winckler, Whei Feng, Jennifer M. Marmion, Elisabeth Laine, Heidi Greulich, Hsiuyi Tseng, Casey Gates, F. Stephen Hodi, Glenn Dranoff, William R. Sellers, Roman K. Thomas, Matthew Meyerson, Todd R. Golub, Reinhard Dummer, Meenhard Herlyn, Gad Getz, and Levi A. Garraway
Cancer Res 2008 68: 664-673. doi: 10.1158/0008-5472.CAN-07-2615 [Abstract] [Full Text] [PDF] Supplementary Data  

Tristetraprolin Down-regulates Interleukin-8 and Vascular Endothelial Growth Factor in Malignant Glioma Cells

Esther Suswam, Yanyan Li, Xiaowen Zhang, G. Yancey Gillespie, Xuelin Li, John J. Shacka, Liang Lu, Lei Zheng, and Peter H. King
Cancer Res 2008 68: 674-682. doi: 10.1158/0008-5472.CAN-07-2751 [Abstract] [Full Text] [PDF]  

Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

Ana Belén Martínez-Cruz, Mirentxu Santos, M. Fernanda Lara, Carmen Segrelles, Sergio Ruiz, Marta Moral, Corina Lorz, Ramón García-Escudero, and Jesús M. Paramio
Cancer Res 2008 68: 683-692. doi: 10.1158/0008-5472.CAN-07-3049 [Abstract] [Full Text] [PDF] Supplementary Data  

TBX3 Is Overexpressed in Breast Cancer and Represses p14^ARF by Interacting with Histone Deacetylases

Will Yarosh, Tomasa Barrientos, Taraneh Esmailpour, Limin Lin, Philip M. Carpenter, Kathryn Osann, Hoda Anton-Culver, and Taosheng Huang
Cancer Res 2008 68: 693-699. doi: 10.1158/0008-5472.CAN-07-5012 [Abstract] [Full Text] [PDF]  

Mitochondrial Cytochrome B Gene Mutation Promotes Tumor Growth in Bladder Cancer

Santanu Dasgupta, Mohammad Obaidul Hoque, Sunil Upadhyay, and David Sidransky
Cancer Res 2008 68: 700-706. doi: 10.1158/0008-5472.CAN-07-5532 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Enhanced Activation of Epidermal Growth Factor Receptor Caused by Tumor-Derived E-Cadherin Mutations

Anja Bremm, Axel Walch, Margit Fuchs, Jörg Mages, Justus Duyster, Gisela Keller, Christine Hermannstädter, Karl-Friedrich Becker, Sandra Rauser, Rupert Langer, Claus Hann von Weyhern, Heinz Höfler, and Birgit Luber
Cancer Res 2008 68: 707-714. doi: 10.1158/0008-5472.CAN-07-1588 [Abstract] [Full Text] [PDF] Supplementary Data  

CCN3/Nephroblastoma Overexpressed Matricellular Protein Regulates Integrin Expression, Adhesion, and Dissemination in Melanoma

Viviana Vallacchi, Maria Daniotti, Francesca Ratti, Delia Di Stasi, Paola Deho, Annamaria De Filippo, Gabrina Tragni, Andrea Balsari, Antonino Carbone, Licia Rivoltini, Giorgio Parmiani, Noureddine Lazar, Bernard Perbal, and Monica Rodolfo
Cancer Res 2008 68: 715-723. doi: 10.1158/0008-5472.CAN-07-2103 [Abstract] [Full Text] [PDF] Supplementary Data  

Modulation of Oncogenic Phenotype in Human Glioma Cells by Cytomegalovirus IE1–Mediated Mitogenicity

Charles S. Cobbs, Liliana Soroceanu, Scott Denham, Wenyue Zhang, and Matthias H. Kraus
Cancer Res 2008 68: 724-730. doi: 10.1158/0008-5472.CAN-07-2291 [Abstract] [Full Text] [PDF]  

Tumor Cell–Secreted Caveolin-1 Has Proangiogenic Activities in Prostate Cancer

Salahaldin A. Tahir, Guang Yang, Alexei A. Goltsov, Masami Watanabe, Ken-ichi Tabata, Josephine Addai, El Moataz Abdel Fattah, Dov Kadmon, and Timothy C. Thompson
Cancer Res 2008 68: 731-739. doi: 10.1158/0008-5472.CAN-07-2668 [Abstract] [Full Text] [PDF]  

The Tumor Suppressor LKB1 Regulates Lung Cancer Cell Polarity by Mediating cdc42 Recruitment and Activity

Shumin Zhang, Katherine Schafer-Hales, Fadlo R. Khuri, Wei Zhou, Paula M. Vertino, and Adam I. Marcus
Cancer Res 2008 68: 740-748. doi: 10.1158/0008-5472.CAN-07-2989 [Abstract] [Full Text] [PDF] Supplementary Data  

The Human Trithorax Protein hASH2 Functions as an Oncoprotein

Juliane Lüscher-Firzlaff, Isabella Gawlista, Jörg Vervoorts, Karsten Kapelle, Till Braunschweig, Gesa Walsemann, Chantal Rodgarkia-Schamberger, Henning Schuchlautz, Stephan Dreschers, Elisabeth Kremmer, Richard Lilischkis, Christa Cerni, Axel Wellmann, and Bernhard Lüscher
Cancer Res 2008 68: 749-758. doi: 10.1158/0008-5472.CAN-07-3158 [Abstract] [Full Text] [PDF]  

Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas

Cristina M. Contreras, Sushma Gurumurthy, J. Marshall Haynie, Lane J. Shirley, Esra A. Akbay, Shana N. Wingo, John O. Schorge, Russell R. Broaddus, Kwok-Kin Wong, Nabeel Bardeesy, and Diego H. Castrillon
Cancer Res 2008 68: 759-766. doi: 10.1158/0008-5472.CAN-07-5014 [Abstract] [Full Text] [PDF]  

Sixteen–Kinase Gene Expression Identifies Luminal Breast Cancers with Poor Prognosis

Pascal Finetti, Nathalie Cervera, Emmanuelle Charafe-Jauffret, Christian Chabannon, Colette Charpin, Max Chaffanet, Jocelyne Jacquemier, Patrice Viens, Daniel Birnbaum, and François Bertucci
Cancer Res 2008 68: 767-776. doi: 10.1158/0008-5472.CAN-07-5516 [Abstract] [Full Text] [PDF] Supplementary Data  

Genotoxic Stress–Induced Expression of p53 and Apoptosis in Leukemic Clam Hemocytes with Cytoplasmically Sequestered p53

Stefanie Böttger, Emily Jerszyk, Ben Low, and Charles Walker
Cancer Res 2008 68: 777-782. doi: 10.1158/0008-5472.CAN-06-0968 [Abstract] [Full Text] [PDF]  

BCL6 Represses Smad Signaling in Transforming Growth Factor-β Resistance

Degang Wang, Jianyin Long, Fangyan Dai, Min Liang, Xin-Hua Feng, and Xia Lin
Cancer Res 2008 68: 783-789. doi: 10.1158/0008-5472.CAN-07-0008 [Abstract] [Full Text] [PDF]  

CD43, but not P-Selectin Glycoprotein Ligand-1, Functions as an E-Selectin Counter-Receptor in Human Pre-B–Cell Leukemia NALL-1

Chizu Nonomura, Jiro Kikuchi, Nobutaka Kiyokawa, Hidenori Ozaki, Kanae Mitsunaga, Hidenobu Ando, Akiko Kanamori, Reiji Kannagi, Junichiro Fujimoto, Kazuo Muroi, Yusuke Furukawa, and Mitsuru Nakamura
Cancer Res 2008 68: 790-799. doi: 10.1158/0008-5472.CAN-07-1459 [Abstract] [Full Text] [PDF]  

ABCG2 Expression and Side Population Abundance Regulated by a Transforming Growth Factor β–Directed Epithelial-Mesenchymal Transition

Liqun Yin, Paola Castagnino, and Richard K. Assoian
Cancer Res 2008 68: 800-807. doi: 10.1158/0008-5472.CAN-07-2545 [Abstract] [Full Text] [PDF] Supplementary Data  

Repression of B-Cell Linker (BLNK) and B-Cell Adaptor for Phosphoinositide 3-Kinase (BCAP) Is Important for Lymphocyte Transformation by Rel Proteins

Nupur Gupta, Jeffrey Delrow, Amar Drawid, Anirvan M. Sengupta, Gaofeng Fan, and Céline Gélinas
Cancer Res 2008 68: 808-814. doi: 10.1158/0008-5472.CAN-07-3169 [Abstract] [Full Text] [PDF] Supplementary Data  

The EGFR-STAT3 Oncogenic Pathway Up-regulates the Eme1 Endonuclease to Reduce DNA Damage after Topoisomerase I Inhibition

Arnaud Vigneron, Erick Gamelin, and Olivier Coqueret
Cancer Res 2008 68: 815-825. doi: 10.1158/0008-5472.CAN-07-5115 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Tamoxifen Resistance in Breast Tumors Is Driven by Growth Factor Receptor Signaling with Repression of Classic Estrogen Receptor Genomic Function

Suleiman Massarweh, C. Kent Osborne, Chad J. Creighton, Lanfang Qin, Anna Tsimelzon, Shixia Huang, Heidi Weiss, Mothaffar Rimawi, and Rachel Schiff
Cancer Res 2008 68: 826-833. doi: 10.1158/0008-5472.CAN-07-2707 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibition of Endoplasmic Reticulum Stress–Induced Apoptosis of Melanoma Cells by the ARC Protein

Li Hua Chen, Chen Chen Jiang, Ralph Watts, Rick F. Thorne, Kelly A. Kiejda, Xu Dong Zhang, and Peter Hersey
Cancer Res 2008 68: 834-842. doi: 10.1158/0008-5472.CAN-07-5056 [Abstract] [Full Text] [PDF] Supplementary Data  

Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib

Adel Kardosh, Encouse B. Golden, Peter Pyrko, Jasim Uddin, Florence M. Hofman, Thomas C. Chen, Stan G. Louie, Nicos A. Petasis, and Axel H. Schönthal
Cancer Res 2008 68: 843-851. doi: 10.1158/0008-5472.CAN-07-5555 [Abstract] [Full Text] [PDF]  

Tamoxifen Stimulates the Growth of Cyclin D1–Overexpressing Breast Cancer Cells by Promoting the Activation of Signal Transducer and Activator of Transcription 3

Yuki Ishii, Samuel Waxman, and Doris Germain
Cancer Res 2008 68: 852-860. doi: 10.1158/0008-5472.CAN-07-2879 [Abstract] [Full Text] [PDF]  

Immunology:

Prostate Stem Cell Antigen Vaccination Induces a Long-term Protective Immune Response against Prostate Cancer in the Absence of Autoimmunity

Maria de la Luz Garcia-Hernandez, Andrew Gray, Bolyn Hubby, Otto J. Klinger, and W. Martin Kast
Cancer Res 2008 68: 861-869. doi: 10.1158/0008-5472.CAN-07-0445 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor-Induced Senescent T Cells with Suppressor Function: A Potential Form of Tumor Immune Evasion

Carolina L. Montes, Andrei I. Chapoval, Jonas Nelson, Vbenosa Orhue, Xiaoyu Zhang, Dan H. Schulze, Scott E. Strome, and Brian R. Gastman
Cancer Res 2008 68: 870-879. doi: 10.1158/0008-5472.CAN-07-2282 [Abstract] [Full Text] [PDF]  

Systematic High-Content Proteomic Analysis Reveals Substantial Immunologic Changes in Colorectal Cancer

Uta Berndt, Lars Philipsen, Sebastian Bartsch, Bertram Wiedenmann, Daniel C. Baumgart, Marcus Hämmerle, and Andreas Sturm
Cancer Res 2008 68: 880-888. doi: 10.1158/0008-5472.CAN-07-2923 [Abstract] [Full Text] [PDF] Supplementary Data  

Epitope Landscape in Breast and Colorectal Cancer

Neil H. Segal, D. Williams Parsons, Karl S. Peggs, Victor Velculescu, Ken W. Kinzler, Bert Vogelstein, and James P. Allison
Cancer Res 2008 68: 889-892. doi: 10.1158/0008-5472.CAN-07-3095 [Abstract] [Full Text] [PDF]  

Self-Tolerance Does Not Restrict the CD4+ T-Helper Response against the p53 Tumor Antigen

Marjolein M. Lauwen, Sander Zwaveling, Linda de Quartel, S. Carmela Ferreira Mota, Janine A.C. Grashorn, Cornelis J.M. Melief, Sjoerd H. van der Burg, and Rienk Offringa
Cancer Res 2008 68: 893-900. doi: 10.1158/0008-5472.CAN-07-3166 [Abstract] [Full Text] [PDF]  

Induction of EBV–Latent Membrane Protein 1–Specific MHC Class II–Restricted T-Cell Responses against Natural Killer Lymphoma Cells

Hiroya Kobayashi, Toshihiro Nagato, Miki Takahara, Keisuke Sato, Shoji Kimura, Naoko Aoki, Makoto Azumi, Masatoshi Tateno, Yasuaki Harabuchi, and Esteban Celis
Cancer Res 2008 68: 901-908. doi: 10.1158/0008-5472.CAN-07-3212 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

DR5 Receptor Mediates Anoikis in Human Colorectal Carcinoma Cell Lines

Luciana M. Laguinge, Raed N. Samara, Wenge Wang, Wafik S. El-Deiry, Georgia Corner, Leonard Augenlicht, Lopa Mishra, and J. Milburn Jessup
Cancer Res 2008 68: 909-917. doi: 10.1158/0008-5472.CAN-06-1806 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

Rosa F. Hwang, Todd Moore, Thiruvengadam Arumugam, Vijaya Ramachandran, Keith D. Amos, Armando Rivera, Baoan Ji, Douglas B. Evans, and Craig D. Logsdon
Cancer Res 2008 68: 918-926. doi: 10.1158/0008-5472.CAN-07-5714 [Abstract] [Full Text] [PDF]  

Epidemiology:

Tumor Immunobiological Differences in Prostate Cancer between African-American and European-American Men

Tiffany A. Wallace, Robyn L. Prueitt, Ming Yi, Tiffany M. Howe, John W. Gillespie, Harris G. Yfantis, Robert M. Stephens, Neil E. Caporaso, Christopher A. Loffredo, and Stefan Ambs
Cancer Res 2008 68: 927-936. doi: 10.1158/0008-5472.CAN-07-2608 [Abstract] [Full Text] [PDF] Supplementary Data  

Prevention:

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

Anthony J. Trimboli, Koichi Fukino, Alain de Bruin, Guo Wei, Lei Shen, Stephan M. Tanner, Nicholas Creasap, Thomas J. Rosol, Michael L. Robinson, Charis Eng, Michael C. Ostrowski, and Gustavo Leone
Cancer Res 2008 68: 937-945. doi: 10.1158/0008-5472.CAN-07-2148 [Abstract] [Full Text] [PDF] Supplementary Data  

Raf and MEK Protein Kinases Are Direct Molecular Targets for the Chemopreventive Effect of Quercetin, a Major Flavonol in Red Wine

Ki Won Lee, Nam Joo Kang, Yong-Seok Heo, Evgeny A. Rogozin, Angelo Pugliese, Mun Kyung Hwang, G. Tim Bowden, Ann M. Bode, Hyong Joo Lee, and Zigang Dong
Cancer Res 2008 68: 946-955. doi: 10.1158/0008-5472.CAN-07-3140 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: SNAI1 Silencing and Inhibition of Breast Tumor Growth

Cancer Res 2008 68: 956 [Full Text] [PDF]  

Correction: IFN Signaling in Aggressive Fibromatosis

Cancer Res 2008 68: 956 [Full Text] [PDF]  

Correction: RPS27L Modulates DNA Damage Response

Cancer Res 2008 68: 956 [Full Text] [PDF]  

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