Reviews:

Acting Locally and Globally: Myc's Ever-Expanding Roles on Chromatin

Natalia V. Varlakhanova and Paul S. Knoepfler
Cancer Res 2009 69: 7487-7490. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-4832 [Abstract] [Full Text] [PDF]  

c-Myc and eIF4F Constitute a Feedforward Loop That Regulates Cell Growth: Implications for Anticancer Therapy

Chen-Ju Lin, Abba Malina, and Jerry Pelletier
Cancer Res 2009 69: 7491-7494. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0813 [Abstract] [Full Text] [PDF]  

Metastamir: The Field of Metastasis-Regulatory microRNA Is Spreading

Douglas R. Hurst, Mick D. Edmonds, and Danny R. Welch
Cancer Res 2009 69: 7495-7498. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-2111 [Abstract] [Full Text] [PDF]  

Perspectives in Cancer Research:

Lessons from Applied Ecology: Cancer Control Using an Evolutionary Double Bind

Robert A. Gatenby, Joel Brown, and Thomas Vincent
Cancer Res 2009 69: 7499-7502. Published Online First September 14, 2009. doi: 10.1158/0008-5472.CAN-09-1354 [Abstract] [Full Text] [PDF]  

Meeting Report:

Regulatory Myeloid Suppressor Cells in Health and Disease

Srinivas Nagaraj, Michele Collazo, Cesar A. Corzo, Je-In Youn, Myrna Ortiz, David Quiceno, and Dmitry I. Gabrilovich
Cancer Res 2009 69: 7503-7506. Published Online First September 14, 2009. doi: 10.1158/0008-5472.CAN-09-2152 [Full Text] [PDF]  

Priority Reports:

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

Heather A. Hirsch, Dimitrios Iliopoulos, Philip N. Tsichlis, and Kevin Struhl
Cancer Res 2009 69: 7507-7511. Published Online First September 14, 2009. doi: 10.1158/0008-5472.CAN-09-2994 [Abstract] [Full Text] [PDF]  

Phosphorylation-Dependent Lys⁶³-Linked Polyubiquitination of Daxx Is Essential for Sustained TNF-–Induced ASK1 Activation

Yayoi Fukuyo, Tetsuya Kitamura, Masahiro Inoue, Nobuko T. Horikoshi, Ryuji Higashikubo, Clayton R. Hunt, Anny Usheva, and Nobuo Horikoshi
Cancer Res 2009 69: 7512-7517. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-2148 [Abstract] [Full Text] [PDF]  

Rearrangements and Amplification of IER3 (IEX-1) Represent a Novel and Recurrent Molecular Abnormality in Myelodysplastic Syndromes

David P. Steensma, Jessemy D. Neiger, Julie C. Porcher, J. Jonathan Keats, P. Leif Bergsagel, Thomas R. Dennis, Ryan A. Knudson, Robert B. Jenkins, Rafael Santana-Davila, Rajiv Kumar, and Rhett P. Ketterling
Cancer Res 2009 69: 7518-7523. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1428 [Abstract] [Full Text] [PDF] Supplementary Data  

Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents

Yuval Shaked, Terence Tang, Jill Woloszynek, Laura G. Daenen, Shan Man, Ping Xu, Shi-Rong Cai, Jeffrey M. Arbeit, Emile E. Voest, David J. Chaplin, Jon Smythe, Adrian Harris, Paul Nathan, Ian Judson, Gordon Rustin, Francesco Bertolini, Daniel C. Link, and Robert S. Kerbel
Cancer Res 2009 69: 7524-7528. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-0381 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Pulmonary Vascular Destabilization in the Premetastatic Phase Facilitates Lung Metastasis

Yujie Huang, Nan Song, Yanping Ding, Shaopeng Yuan, Xuhui Li, Hongchen Cai, Hubing Shi, and Yongzhang Luo
Cancer Res 2009 69: 7529-7537. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-4382 [Abstract] [Full Text] [PDF] Supplementary Data  

Melanoma Proteoglycan Modifies Gene Expression to Stimulate Tumor Cell Motility, Growth, and Epithelial-to-Mesenchymal Transition

Jianbo Yang, Matthew A. Price, Gui Yuan Li, Menashe Bar-Eli, Ravi Salgia, Ramasamy Jagedeeswaran, Jennifer H. Carlson, Soldano Ferrone, Eva A. Turley, and James B. McCarthy
Cancer Res 2009 69: 7538-7547. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-08-4626 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidermal Growth Factor Receptor Variant III–Induced Glioma Invasion Is Mediated through Myristoylated Alanine-Rich Protein Kinase C Substrate Overexpression

Johann Micallef, Michael Taccone, Joydeep Mukherjee, Sidney Croul, Jennifer Busby, Michael F. Moran, and Abhijit Guha
Cancer Res 2009 69: 7548-7556. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-4783 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells

James C. Garbe, Sanchita Bhattacharya, Batul Merchant, Ekaterina Bassett, Karen Swisshelm, Heidi S. Feiler, Andrew J. Wyrobek, and Martha R. Stampfer
Cancer Res 2009 69: 7557-7568. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0270 [Abstract] [Full Text] [PDF] Supplementary Data  

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

Yunqing Li, Fadila Guessous, Ying Zhang, Charles DiPierro, Benjamin Kefas, Elizabeth Johnson, Lukasz Marcinkiewicz, Jinmai Jiang, Yanzhi Yang, Thomas D. Schmittgen, Beatriz Lopes, David Schiff, Benjamin Purow, and Roger Abounader
Cancer Res 2009 69: 7569-7576. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0529 [Abstract] [Full Text] [PDF]  

BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells

Mala Mani, Daniel E. Carrasco, Yunyu Zhang, Kohichi Takada, Moshe E. Gatt, Jui Dutta-Simmons, Hiroshi Ikeda, Felipe Diaz-Griffero, Victor Pena-Cruz, Monica Bertagnolli, Lois L. Myeroff, Sanford D. Markowitz, Kenneth C. Anderson, and Daniel R. Carrasco
Cancer Res 2009 69: 7577-7586. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-0773 [Abstract] [Full Text] [PDF] Supplementary Data  

Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

Dae Joon Kim, Ken Kataoka, Dharanija Rao, Kaoru Kiguchi, George Cotsarelis, and John DiGiovanni
Cancer Res 2009 69: 7587-7594. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-1180 [Abstract] [Full Text] [PDF]  

Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF-β–Induced Cell Death through Impairing Up-regulation of the NADPH Oxidase NOX4

Laia Caja, Patricia Sancho, Esther Bertran, Daniel Iglesias-Serret, Joan Gil, and Isabel Fabregat
Cancer Res 2009 69: 7595-7602. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1482 [Abstract] [Full Text] [PDF] Supplementary Data  

Atypical Protein Kinase C Is Required for Bronchioalveolar Stem Cell Expansion and Lung Tumorigenesis

Roderick P. Regala, Rebecca K. Davis, Alyssa Kunz, Andras Khoor, Michael Leitges, and Alan P. Fields
Cancer Res 2009 69: 7603-7611. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-2066 [Abstract] [Full Text] [PDF] Supplementary Data  

Correction of the Abnormal Trafficking of Primary Myelofibrosis CD34⁺ Cells by Treatment with Chromatin-Modifying Agents

Xiaoli Wang, Wei Zhang, Takefumi Ishii, Selcuk Sozer, Jiapeng Wang, Mingjiang Xu, and Ronald Hoffman
Cancer Res 2009 69: 7612-7618. Published Online First September 14, 2009. doi: 10.1158/0008-5472.CAN-09-1823 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

A Role for the Clock Gene Per1 in Prostate Cancer

Qi Cao, Sigal Gery, Azadeh Dashti, Dong Yin, Yan Zhou, Jiang Gu, and H. Phillip Koeffler
Cancer Res 2009 69: 7619-7625. Published Online First September 14, 2009. doi: 10.1158/0008-5472.CAN-08-4199 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Nitrosative Stress–Induced S-Glutathionylation of Protein Disulfide Isomerase Leads to Activation of the Unfolded Protein Response

Danyelle M. Townsend, Yefim Manevich, Lin He, Ying Xiong, Robert R. Bowers, Jr., Steven Hutchens, and Kenneth D. Tew
Cancer Res 2009 69: 7626-7634. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0493 [Abstract] [Full Text] [PDF]  

Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 In vitro

Andrea E. Wahner Hendrickson, Paul Haluska, Paula A. Schneider, David A. Loegering, Kevin L. Peterson, Ricardo Attar, B. Douglas Smith, Charles Erlichman, Marco Gottardis, Judith E. Karp, Joan M. Carboni, and Scott H. Kaufmann
Cancer Res 2009 69: 7635-7643. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-0511 [Abstract] [Full Text] [PDF] Supplementary Data  

Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non–Small Cell Lung Cancer Harboring K-RAS Mutations

Georgia Konstantinidou, Erik A. Bey, Andrea Rabellino, Katja Schuster, Michael S. Maira, Adi F. Gazdar, Augusto Amici, David A. Boothman, and Pier Paolo Scaglioni
Cancer Res 2009 69: 7644-7652. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-0823 [Abstract] [Full Text] [PDF] Supplementary Data  

Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B. Ho, Chris Proffitt, Katy Trent, Jeffrey P. Whitten, John K. C. Lim, Daniel Von Hoff, Kenna Anderes, and William G. Rice
Cancer Res 2009 69: 7653-7661. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-1304 [Abstract] [Full Text] [PDF] Supplementary Data  

The Insulin-like Growth Factor-1 Receptor–Targeting Antibody, CP-751,871, Suppresses Tumor-Derived VEGF and Synergizes with Rapamycin in Models of Childhood Sarcoma

Raushan T. Kurmasheva, Lorina Dudkin, Catherine Billups, Larisa V. Debelenko, Christopher L. Morton, and Peter J. Houghton
Cancer Res 2009 69: 7662-7671. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1693 [Abstract] [Full Text] [PDF] Supplementary Data  

Preclinical Profile of a Potent -Secretase Inhibitor Targeting Notch Signaling with In vivo Efficacy and Pharmacodynamic Properties

Leopoldo Luistro, Wei He, Melissa Smith, Kathryn Packman, Maria Vilenchik, Daisy Carvajal, John Roberts, James Cai, Windy Berkofsky-Fessler, Holly Hilton, Michael Linn, Alexander Flohr, Roland Jakob-Røtne, Helmut Jacobsen, Kelli Glenn, David Heimbrook, and John F. Boylan
Cancer Res 2009 69: 7672-7680. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1843 [Abstract] [Full Text] [PDF] Supplementary Data  

Mutant p53 Disrupts the Stress MAPK Activation Circuit Induced by ASK1-Dependent Stabilization of Daxx

Tetsuya Kitamura, Yayoi Fukuyo, Masahiro Inoue, Nobuko T. Horikoshi, Masanobu Shindoh, Buck E. Rogers, Anny Usheva, and Nobuo Horikoshi
Cancer Res 2009 69: 7681-7688. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-2133 [Abstract] [Full Text] [PDF] Supplementary Data  

A Small Molecule Polyamine Oxidase Inhibitor Blocks Androgen-Induced Oxidative Stress and Delays Prostate Cancer Progression in the Transgenic Adenocarcinoma of the Mouse Prostate Model

Hirak S. Basu, Todd A. Thompson, Dawn R. Church, Cynthia C. Clower, Farideh Mehraein-Ghomi, Corey A. Amlong, Christopher T. Martin, Patrick M. Woster, Mary J. Lindstrom, and George Wilding
Cancer Res 2009 69: 7689-7695. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-2472 [Abstract] [Full Text] [PDF]  

Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling

Liangli Zhao, Brian Y. Lee, David A. Brown, Mark P. Molloy, Gavin M. Marx, Nick Pavlakis, Michael J. Boyer, Martin R. Stockler, Warren Kaplan, Samuel N. Breit, Robert L. Sutherland, Susan M. Henshall, and Lisa G. Horvath
Cancer Res 2009 69: 7696-7703. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-4901 [Abstract] [Full Text] [PDF] Supplementary Data  

c-Jun Protects Hypoxia-Inducible Factor-1 from Degradation via Its Oxygen-Dependent Degradation Domain in a Nontranscriptional Manner

Bing Yu, Ze-Hong Miao, Yi Jiang, Mei-Hong Li, Na Yang, Ting Li, and Jian Ding
Cancer Res 2009 69: 7704-7712. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-0808 [Abstract] [Full Text] [PDF] Supplementary Data  

Expression of IFN-β Enhances Both Efficacy and Safety of Oncolytic Vesicular Stomatitis Virus for Therapy of Mesothelioma

Candice L. Willmon, Vassiliki Saloura, Zvi G. Fridlender, Phonphimon Wongthida, Rosa Maria Diaz, Jill Thompson, Timothy Kottke, Mark Federspiel, Glen Barber, Steven M. Albelda, and Richard G. Vile
Cancer Res 2009 69: 7713-7720. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1013 [Abstract] [Full Text] [PDF]  

[¹⁸F]Fluoromethyl-[1,2-²H₄]-Choline: A Novel Radiotracer for Imaging Choline Metabolism in Tumors by Positron Emission Tomography

Julius Leyton, Graham Smith, Yongjun Zhao, Meg Perumal, Quang-De Nguyen, Edward Robins, Erik Årstad, and Eric O. Aboagye
Cancer Res 2009 69: 7721-7728. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1419 [Abstract] [Full Text] [PDF] Supplementary Data  

Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

Herman H. Cheung, Douglas J. Mahoney, Eric C. LaCasse, and Robert G. Korneluk
Cancer Res 2009 69: 7729-7738. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1794 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of a Small Molecule Inhibitor of the Human DNA Repair Enzyme Polynucleotide Kinase/Phosphatase

Gary K. Freschauf, Feridoun Karimi-Busheri, Agnieszka Ulaczyk-Lesanko, Todd R. Mereniuk, Ashley Ahrens, Jonathan M. Koshy, Aghdass Rasouli-Nia, Phuwadet Pasarj, Charles F.B. Holmes, Frauke Rininsland, Dennis G. Hall, and Michael Weinfeld
Cancer Res 2009 69: 7739-7746. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1805 [Abstract] [Full Text] [PDF]  

Immunology:

Tumor Vaccines Expressing Flt3 Ligand Synergize with CTLA-4 Blockade to Reject Preimplanted Tumors

Michael A. Curran and James P. Allison
Cancer Res 2009 69: 7747-7755. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-08-3289 [Abstract] [Full Text] [PDF]  

Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8⁺ T-Cell Anergy and CD4⁺ Tr1 Cell Responses

Yufeng Xie, Ou Bai, Jinying Yuan, Rajni Chibbar, Karen Slattery, Yangdou Wei, Yulin Deng, and Jim Xiang
Cancer Res 2009 69: 7756-7766. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-0496 [Abstract] [Full Text] [PDF] Supplementary Data  

Antitumor Immunity Can Be Uncoupled from Autoimmunity following Heat Shock Protein 70–Mediated Inflammatory Killing of Normal Pancreas

Timothy Kottke, Jose Pulido, Jill Thompson, Luis Sanchez-Perez, Heung Chong, Stuart K. Calderwood, Peter Selby, Kevin Harrington, Scott E. Strome, Alan Melcher, and Richard G. Vile
Cancer Res 2009 69: 7767-7774. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-1597 [Abstract] [Full Text] [PDF]  

Platelet-Derived Transforming Growth Factor-β Down-Regulates NKG2D Thereby Inhibiting Natural Killer Cell Antitumor Reactivity

Hans-Georg Kopp, Theresa Placke, and Helmut Rainer Salih
Cancer Res 2009 69: 7775-7783. Published Online First September 8, 2009. doi: 10.1158/0008-5472.CAN-09-2123 [Abstract] [Full Text] [PDF]  

Design of Agonistic Altered Peptides for the Robust Induction of CTL Directed towards H-2D^b in Complex with the Melanoma-Associated Epitope gp100

Marianne J.B. van Stipdonk, Daniel Badia-Martinez, Marjolein Sluijter, Rienk Offringa, Thorbald van Hall, and Adnane Achour
Cancer Res 2009 69: 7784-7792. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1724 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Comparative Analyses of Chromosome Alterations in Soft-Tissue Metastases within and across Patients with Castration-Resistant Prostate Cancer

Ilona N. Holcomb, Janet M. Young, Ilsa M. Coleman, Keyan Salari, Douglas I. Grove, Li Hsu, Lawrence D. True, Martine P. Roudier, Colm M. Morrissey, Celestia S. Higano, Peter S. Nelson, Robert L. Vessella, and Barbara J. Trask
Cancer Res 2009 69: 7793-7802. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-3810 [Abstract] [Full Text] [PDF] Supplementary Data  

MYC Activity Mitigates Response to Rapamycin in Prostate Cancer through Eukaryotic Initiation Factor 4E–Binding Protein 1–Mediated Inhibition of Autophagy

Bala S. Balakumaran, Alessandro Porrello, David S. Hsu, Wayne Glover, Adam Foye, Janet Y. Leung, Beth A. Sullivan, William C. Hahn, Massimo Loda, and Phillip G. Febbo
Cancer Res 2009 69: 7803-7810. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0910 [Abstract] [Full Text] [PDF] Supplementary Data  

An A13 Repeat within the 3'-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression

Ziqiang Yuan, Joongho Shin, Andrew Wilson, Sanjay Goel, Yi-He Ling, Naseem Ahmed, Higinio Dopeso, Minaxi Jhawer, Shannon Nasser, Cristina Montagna, Kenneth Fordyce, Leonard H. Augenlicht, Lauri A. Aaltonen, Diego Arango, Thomas K. Weber, and John M. Mariadason
Cancer Res 2009 69: 7811-7818. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-0986 [Abstract] [Full Text] [PDF] Supplementary Data  

Role of SV40 Integration Site at Chromosomal Interval 1q21.1 in Immortalized CRL2504 Cells

Jinglan Liu, Gurpreet Kaur, Vikramjit K. Zhawar, Drazen B. Zimonjic, Nicholas C. Popescu, Raj P. Kandpal, and Raghbir S. Athwal
Cancer Res 2009 69: 7819-7825. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1003 [Abstract] [Full Text] [PDF]  

Immutable Functional Attributes of Histologic Grade Revealed by Context-Independent Gene Expression in Primary Breast Cancer Cells

Shanaz H. Dairkee, Aejaz Sayeed, Gloria Luciani, Stacey Champion, Zhenhang Meng, Lakshmi R. Jakkula, Heidi S. Feiler, Joe W. Gray, and Dan H. Moore
Cancer Res 2009 69: 7826-7834. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1564 [Abstract] [Full Text] [PDF] Supplementary Data  

Extracellular Signal-Regulated Kinase Positively Regulates the Oncogenic Activity of MCT-1 in Diffuse Large B-Cell Lymphoma

Bojie Dai, X. Frank Zhao, Patrick Hagner, Paul Shapiro, Krystyna Mazan-Mamczarz, Shuchun Zhao, Yasodha Natkunam, and Ronald B. Gartenhaus
Cancer Res 2009 69: 7835-7843. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1606 [Abstract] [Full Text] [PDF] Supplementary Data  

Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1

Yan Liu, Pengyuan Liu, Weidong Wen, Michael A. James, Yian Wang, Joan E. Bailey-Wilson, Christopher I. Amos, Susan M. Pinney, Ping Yang, Mariza de Andrade, Gloria M. Petersen, Jonathan S. Wiest, Pamela R. Fain, Ann G. Schwartz, Adi Gazdar, Colette Gaba, Henry Rothschild, Diptasri Mandal, Elena Kupert, Juwon Lee, Daniela Seminara, John Minna, Marshall W. Anderson, and Ming You
Cancer Res 2009 69: 7844-7850. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1833 [Abstract] [Full Text] [PDF] Supplementary Data  

TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation

Zhongkui Li, Zhe Chang, Lucia J. Chiao, Ya'an Kang, Qianghua Xia, Cihui Zhu, Jason B. Fleming, Douglas B. Evans, and Paul J. Chiao
Cancer Res 2009 69: 7851-7859. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-08-4002 [Abstract] [Full Text] [PDF] Supplementary Data  

Systems Biology and Emerging Technologies:

Circulating Tumor Cells Are Transcriptionally Similar to the Primary Tumor in a Murine Prostate Model

Kimberly T. Helzer, Helen E. Barnes, Laura Day, Jeanne Harvey, Paul R. Billings, and Allyn Forsyth
Cancer Res 2009 69: 7860-7866. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-0801 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

Adipocytes Impair Leukemia Treatment in Mice

James W. Behan, Jason P. Yun, Marina P. Proektor, Ehsan A. Ehsanipour, Anna Arutyunyan, Ara S. Moses, Vassilios I. Avramis, Stan G. Louie, Anna Butturini, Nora Heisterkamp, and Steven D. Mittelman
Cancer Res 2009 69: 7867-7874. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-0800 [Abstract] [Full Text] [PDF] Supplementary Data  

Vascular Adhesion Protein-1 Enhances Tumor Growth by Supporting Recruitment of Gr-1⁺CD11b⁺ Myeloid Cells into Tumors

Fumiko Marttila-Ichihara, Kaisa Auvinen, Kati Elima, Sirpa Jalkanen, and Marko Salmi
Cancer Res 2009 69: 7875-7883. Published Online First September 29, 2009. doi: 10.1158/0008-5472.CAN-09-1205 [Abstract] [Full Text] [PDF] Supplementary Data  

Blockade of a Chemokine, CCL2, Reduces Chronic Colitis-Associated Carcinogenesis in Mice

Boryana Konstantinova Popivanova, Feodora Ivanova Kostadinova, Kengo Furuichi, Mohamed M. Shamekh, Toshikazu Kondo, Takashi Wada, Kensuke Egashira, and Naofumi Mukaida
Cancer Res 2009 69: 7884-7892. Published Online First September 22, 2009. doi: 10.1158/0008-5472.CAN-09-1451 [Abstract] [Full Text] [PDF] Supplementary Data  

Letter to the Editor:

Comment Re: MDA-MB-435 and M14 Cell Lines: Identical but not M14 Melanoma?

Antoinette Hollestelle and Mieke Schutte
Cancer Res 2009 69: 7893. Published Online First September 1, 2009. doi: 10.1158/0008-5472.CAN-09-2396 [Full Text] [PDF]  

Corrections:

Correction: Article on Breast Cancer Tumor Progression

Cancer Res 2009 69: 7894. doi: 10.1158/0008-5472.CAN-69-19-COR1 [Full Text] [PDF]  

Correction: Review Article on Clonal Mutations in the Cancer-Associated Fibroblasts

Cancer Res 2009 69: 7894. doi: 10.1158/0008-5472.CAN-69-19-COR2 [Full Text] [PDF]  

Correction: Article on PTHrP Stabilizes AR and Enhances Prostate Cancer Growth

Cancer Res 2009 69: 7894. doi: 10.1158/0008-5472.CAN-69-19-COR3 [Full Text] [PDF]  

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